[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617295":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":39,"responsibleParty":54,"collaborators":58,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":11,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":11,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":84,"overallStatus":91,"whyStopped":11,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Liege","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Eccentric group","EXPERIMENTAL",null,[13],"Other: Eccentric training",{"label":15,"type":16,"description":11,"interventionNames":17},"Concentric group","ACTIVE_COMPARATOR",[18],"Other: Concentric training",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Eccentric training","Eccentric cycling training",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Concentric training","Concentric cycling training",[15],[29],{"name":30,"affiliation":31,"role":32},"Stéphanie HODY, PhD","Department of Physical Activity and Rehabilitation Sciences, University of Liege and University Hospital of Liege, Liege, Belgium","STUDY_CHAIR",[34],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Benoît Vandenbroeck, PhD Student","CONTACT","+32474271843","benoit.vandenbroeck@uliege.be",[40],{"facility":41,"status":11,"city":42,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Liege University","Liège","4000","Belgium","BE",{"type":47,"coordinates":48},"Point",[49,50],5.56749,50.63373,{"lat":50,"lon":49},[53],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Vandenbroeck Benoit","Physiotherapist",[59],{"name":60,"class":61},"University Hospital Sart Tilman, Liege","UNKNOWN","100617295","eccentric-cycling-in-multiple-sclerosis-rehabilitation-100617295",false,"NCT07316764","Eccentric Cycling in Multiple Sclerosis Rehabilitation","Eccentric Cycling : a New Training Modality in Multiple Sclerosis Rehabilitation","Inclusion Criteria:\n\n* Diagnosis of multiple sclerosis\n* Multiple sclerosis: EDSS score \\\u003C 7\n* Age under 75 years\n* Stable disease state\n* Written medical clearance authorizing participation\n* Legal adult status\n* Written informed consent, with demonstrated understanding of the consent form (via a few specific questions)\n* Ability to mobilize independently (e.g., transfers, walking)\n\nExclusion Criteria:\n\n* One or more contraindications to physical activity\n* Significant comorbidities\n* Current hospitalization or undergoing changes in medication\n* Active flare-up","ALL","18 Years","75 Years",{"count":73,"type":74},60,"ESTIMATED","INTERVENTIONAL",[77],"NA","The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis.\n\nInvestigators are proposing eccentric cycling as a new exercise modality for treating these patients.\n\nBased on previous results in healthy subjects, investigators will attempt to define the optimal parameters of this new modality (in terms of duration, intensity, frequency, etc.).\n\nInvestigators also aim to demonstrate the effectiveness of this training (compared to conventional training) in improving muscle function, functional capacity, perception of chronic fatigue, quality of life, physical condition, and neurological and cognitive function.",[80,81,82,83],"Multiple Sclerosis","Rehabilitation","Neuro-Degenerative Disease","Neurorehabilitation",[85,86,87,88,89,90],"eccentric cycling","multiple sclerosis","eccentric training","neurorehabilitation","physical therapy","neuro-degenerative disease","NOT_YET_RECRUITING","2025-12-23",{"date":94,"type":95},"2026-01-05","ACTUAL",{"date":97,"type":74},"2026-01",{"date":99,"type":74},"2026-12",{"name":5,"class":6},1]