[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621008":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":67,"collaborators":40,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":40,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":49,"whyStopped":40,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"interventional group A","EXPERIMENTAL","The interventional group will receive eccentric wrist extensor exercises combined with blood flow restriction therapy, using a pneumatic cuff inflated to 50-60% limb occlusion pressure. Exercises will be performed at 20-30% 1-RM using a 30-15-15-15 repetition protocol, emphasizing slow controlled eccentric contractions. Sessions will be conducted three times weekly for 8 weeks, totaling 24 supervised sessions.",[13],"Behavioral: interventional group A",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group B","ACTIVE_COMPARATOR","The control group will undergo a heavy slow resistance training protocol, involving wrist extensor exercises performed at 70-85% of 1-RM, with slow concentric and eccentric phases (3 seconds each). Participants will complete 3-4 sets of 6-8 repetitions, with adequate rest intervals, following the same session frequency and duration as the intervention group.",[19],"Behavioral: control group b",[21,26],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL",[9],[25],"blood flow resistance training",{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":29},"control group b",[15],[30],"resistance training",[32],{"name":33,"affiliation":34,"role":35},"Nimra Rafiq, MS MSK","The University of Lahore, Lahore","PRINCIPAL_INVESTIGATOR",[37,42],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","0333 4170217",null,"701747512@student.uol.edu.pk",{"name":43,"role":38,"phone":44,"phoneExt":40,"email":45},"Montiha Azeem, MSPTN","03479717317","muntahaazeem9@gmail.com",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"University of Lahore Teaching Hospital, Lahore","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":56,"coordinates":57},"Point",[58,59],74.35071,31.558,{"lat":59,"lon":58},[62,65,66],{"name":33,"role":38,"phone":63,"phoneExt":40,"email":64},"03334170217","37nimrarafiq@gmail.com",{"name":43,"role":38,"phone":44,"phoneExt":40,"email":45},{"name":33,"role":35,"phone":40,"phoneExt":40,"email":40},{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"SPONSOR_INVESTIGATOR","Nimra Rafiq","principal investigator","100621008","eccentric-exercise-with-blood-flow-restriction-vs-resistance-training-for-lateral-epicondylitis-100621008",false,"NCT07365033","Eccentric Exercise With Blood Flow Restriction vs Resistance Training for Lateral Epicondylitis","Effectiveness of Eccentric Training With Blood Flow Restriction Therapy Versus Resistance Training in Patients With Lateral Epicondylitis","BFR-ET LE","Inclusion Criteria:\n\nPatient aged between 25 and 45 years. Both male and female participants with unilateral symptoms only. Clinically diagnosed unilateral lateral epicondylitis (LE), confirmed by positive Cozen's and Mills' tests. Symptom duration exceeding 12 months, indicating chronic LE.\n\nExclusion Criteria:\n\nPrevious history of surgery or injection therapy for LE within the past 6 months.\n\nCoexisting conditions (e.g., rheumatoid arthritis, cervical radiculopathy, significant tendon tears). Contraindications to BFR (e.g., DVT, vascular disease, uncontrolled hypertension, clotting disorders).\n\nUse of anticoagulants or long-term pain medications. Pregnant or psychological person.","ALL","25 Years","45 Years",{"count":83,"type":84},40,"ESTIMATED","INTERVENTIONAL",[87],"NA","This randomized controlled trial aims to compare the effectiveness of eccentric training combined with blood flow restriction (ECC+BFR) versus heavy slow resistance (HSR) training in patients with chronic lateral epicondylitis. The study will recruit 40 participants (accounting for 10% attrition), aged 25-45 years, from Sakina Memorial Hospital Sheikhupura and University of Lahore Teaching Hospital using convenience sampling. Participants will be randomly allocated into two groups: an interventional group receiving ECC+BFR and a control group undergoing HSR training. Both interventions will be administered three times per week for 8 weeks under professional supervision. Outcome measures including pain intensity (NPRS), patient-specific functional performance (PSFS), muscle strength, and hypertrophy will be assessed at baseline, 4 weeks, and 8 weeks. Data will be analyzed using SPSS, with appropriate parametric or non-parametric tests applied after checking data normality. Ethical approval will be obtained, informed consent will be secured, and participant confidentiality will be strictly maintained.",[90],"Lateral Epicondylitis",[90,92,93,94],"Blood Flow Restriction Therapy","Eccentric Training","Resistance Training,","2026-02-04",{"date":97,"type":98},"2026-02-05","ACTUAL",{"date":100,"type":84},"2026-01-30",{"date":102,"type":84},"2026-03-31",{"name":69,"class":6},1]