[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609228":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":35,"centralContacts":40,"locations":46,"responsibleParty":61,"collaborators":65,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":44,"enrollmentInfo":80,"targetDuration":44,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":48,"whyStopped":44,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"China Medical University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sedation with high dose of alfentanil with the presence of propofol","EXPERIMENTAL","Adjust dose of alfentanil until reaching to the upper limit before adjusting dose of propofol. This aims to have a highest dose of alfentanil during anesthesia.",[13],"Drug: high dose of alfentanil",{"label":15,"type":16,"description":17,"interventionNames":18},"Sedation with low dose of alfentanil with the presence of propofol","ACTIVE_COMPARATOR","Adjust dose of propofol to the upper limit before adjusting dose of alfentanil. This aims to have alfentanil less or equal to 10ng\u002FmL during anesthesia.",[19],"Drug: low dose of alfentanil with propofol",[21,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","high dose of alfentanil","The initial dose is alfentanil cet 10ng\u002FmL and propofol 1ug\u002FmL. Dose of alfentanil will be increased by 10ng\u002FmL each until PSI reach to 25-50. If alfentail has been adjusted to 50 but PSI is still too high, increase propofol cet by 0.5-1ug\u002FmL till target PSI is reached. If propofol is adjusted to 0 but PSI is still too low, decrease alfetanil by 10ng\u002FmL The range of dosage of alfentanil is 0-50ng\u002FmL while propofol is 0-5ug\u002FmL.",[9],[27,28,29],"Alfenta","Alfentanil hydrochloride","Propofol (Diprivan)",{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"low dose of alfentanil with propofol","Adjust dose of propofol to the upper limit before adjusting dose of alfentanil. Increase dose of propofol 0.5-1 ug\u002FmL in order to have PSI valued 25-50. The initial dose of propofol is 1ug\u002FmL, alfentanil 10 ng\u002FmL. If propofol was adjusted to cet=5 ug\u002FmL but PSI is still too high, increase alfentanil by 10 ng\u002FmL instead. If alfentanil was adjusted to 0 but PSI is still too low, decrease propofol by 0.5-1 ug\u002FmL instead . The range of dosage of propofol is 0-5 ug\u002FmL while alfentanil is 0-50ng\u002FmL.",[15],[29,27,28],[36],{"name":37,"affiliation":38,"role":39},"Chi Kwan Boris Fung, MD","Wei Gong Memorial Hospital","PRINCIPAL_INVESTIGATOR",[41],{"name":37,"role":42,"phone":43,"phoneExt":44,"email":45},"CONTACT","886-037-676811",null,"024666@tool.caaumed.org.tw",[47],{"facility":38,"status":48,"city":49,"state":44,"zip":44,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Miaoli","Taiwan","TW",{"type":53,"coordinates":54},"Point",[55,56],120.82367,24.56427,{"lat":56,"lon":55},[59],{"name":37,"role":42,"phone":60,"phoneExt":44,"email":45},"886-037-676818",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":44,"oldOrganization":44},"SPONSOR_INVESTIGATOR","Chi Kwan Fung","Attendant Physician",[66,68],{"name":67,"class":6},"National Yang Ming Chiao Tung University",{"name":69,"class":6},"WeiGong Memorial Hospital","100609228","eeg-and-pain-monitor-data-under-anesthesia-to-study-pharmacodynamic-effects-of-opioids-and-sedatives-100609228",false,"NCT07211828","EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives","Pharmacodynamic Effects of Propofol and Alfentanil on EEG During Endoscopic Retrograde Cholangiopancreatography (ERCP)","SED-ERCP","Inclusion Criteria:\n\n* Patients who under go ERCP who require general anesthesia\n\nExclusion Criteria:\n\n* ASA\\> or = 4 , vulnerable groups such as prisoners, patients with physical or mental disabilities and HIV carriers","ALL","18 Years",{"count":81,"type":82},20,"ESTIMATED","INTERVENTIONAL",[85],"NA","Recording and analyzing electroencephalogram (EEG) and continuous pain monitor data under anesthesia in order to investigating the pharmacodynamic effects of opioids and sedatives.",[88,89,90],"Sedation and Analgesia","Cholangiopancreatography, Endoscopic Retrograde","Anesthesia, General",[92,93,94,95],"sedation","phramacodynamics","opioid","ERCP","2026-03-24",{"date":98,"type":99},"2026-03-27","ACTUAL",{"date":101,"type":99},"2025-10-10",{"date":103,"type":82},"2028-06-16",{"name":63,"class":6},1]