[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560177":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":65,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":26,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Loughborough University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bioactive whey protein concentrate supplement group","EXPERIMENTAL","This group will consume a supplement called bioactive whey protein concentrate, a whey protein concentrate that contains milk fat globule membrane.",[13],"Dietary Supplement: Bioactive whey protein concentrate",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","This group will consume an isocaloric, isonitrogenous whey protein isolate supplement that does not contain phospholipids or sphingomyelin. Dextrose has been added to the whey protein isolate to ensure the 2 supplements are isocaloric.",[19],"Dietary Supplement: Whey protein isolate supplement",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Bioactive whey protein concentrate","Every day for 12 weeks, participants will mix 1 scoop of supplement with \\~350ml of water and consume the resultant drink alongside their breakfast.",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Whey protein isolate supplement",[15],[31],{"name":32,"affiliation":5,"role":33},"Edward Sadula, BSc, MSc","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","07477 866809","e.sadula2@lboro.ac.uk",{"name":40,"role":36,"phone":41,"phoneExt":26,"email":42},"Jonathan Folland, BSc, PhD","01509 226334","J.P.Folland@lboro.ac.uk",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Loughborough","Leicestershire","LE11 3TU","United Kingdom","UK",{"type":52,"coordinates":53},"Point",[54,55],-1.2,52.76667,{"lat":55,"lon":54},[58],{"name":59,"role":36,"phone":60,"phoneExt":26,"email":61},"Jennifer Johnson","1509 226769","j.j.johnson@lboro.ac.uk",{"type":33,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Edward Sadula","Doctoral Researcher",[66],{"name":67,"class":68},"Volac International Limited","UNKNOWN","100560177","effect-of-12-week-milk-fat-globule-membrane-supplementation-on-the-human-muscle-function-of-healthy-recreationally-active-adults-100560177",false,"NCT06573749","Effect of 12-week Milk Fat Globule Membrane Supplementation on the Human Muscle Function of Healthy, Recreationally Active Adults","Effect of 12-week Bioactive Whey Protein Concentrate Supplementation on the Neuromuscular System of Healthy, Recreationally Active Adults","Inclusion Criteria:\n\n* 18-30 or 60-75 years old\n* Male or female\n* Healthy with no contraindications to exercise\n* Classified as recreationally active (meet the government's guidelines for weekly physical activity - 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity)\n\nExclusion Criteria:\n\n* Any injury, medical condition or symptom precluding the ability to complete strenuous exercise as identified by the health screen questionnaire and physical activity readiness questionnaire\n* Uncontrolled hypertension (blood pressure of 140\u002F90 mmHg or higher) as identified by recording resting blood pressure\n* Neuromuscular or musculoskeletal disease\n* Occurrence of a severe injury to the lower limbs or back within the previous 6 months (time loss of \\> 21 days of normal activity)\n* Occurrence of a minor injury to the lower limbs or back within the previous month (time loss of \\>1 day of normal activity)\n* Do not meet the government guidelines of minimum weekly physical activity as revealed by the IPAQ-SF\n* Allergic to dairy or pea, or lactose intolerant\n* Complete greater than 6 hours structured exercise per week as revealed by the exercise and physical activity form\n* Consumption of supplements that may confound the results of the present study within the previous 3 months (includes any form of protein supplement, creatine, pre-workout supplements, any form of testosterone supplement, amino acids, beta-alanine, beta- hydroxy-beta-methylbutyrate (HMB), fish or krill oil, collagen supplements, any choline- containing supplement, or any phospholipid-containing supplement) as highlighted by the health screen questionnaire\n* Taking anticoagulants or antiplatelet drugs\n* Use of antidepressant\u002Fanti-anxiety medication\n* Having a blood borne virus, or a partner who has a blood-borne virus\n* Extreme diet classified as identified by the food-frequency questionnaire",true,"ALL","18 Years","75 Years",{"count":81,"type":82},96,"ESTIMATED","INTERVENTIONAL",[85],"NA","The main aim of this study is to understand if chronic supplementation (12 weeks) of a milk fat globule membrane containing supplement, called bioactive whey protein concentrate, improves human muscle function greater than a placebo supplement within a cohort of healthy, recreationally active adults. Furthermore, we aim to investigate whether any potential benefits of milk fat globule membrane are influenced by age through the assessment of 2 distinct age subgroups (young and older). We hypothesise that neuromuscular function (strength and power) will increase from pre to post within the group that consumes bioactive whey protein concentrate but not the placebo group, with a greater increase in the older group compared to the young group.",[88,89],"Ageing Well","Neuromuscular Function",[91,92,93],"Nutrition","Neuromuscular","Milk fat globule membrane","2025-03-28",{"date":96,"type":97},"2025-04-02","ACTUAL",{"date":94,"type":97},{"date":100,"type":82},"2026-01",{"name":5,"class":6},1]