[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643938":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":53,"collaborators":18,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":18,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":18,"overallStatus":75,"whyStopped":18,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Asklepios proresearch","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cervical pessary plus standard care","EXPERIMENTAL","Participants receive placement of an Arabin cervical pessary between 20 and 30 weeks of gestation in addition to standard care. Pessary position is monitored by ultrasound at regular 4-week intervals until delivery. The pessary is removed at the onset of labor, before planned cesarean delivery, or earlier if clinically indicated because of complications such as infection or intolerance.",[13],"Device: Cervical pessary",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard care","NO_INTERVENTION","Participants receive standard guideline-based management without placement of a cervical pessary. Clinical assessment and ultrasound follow-up are performed at the same regular 4-week intervals as in the intervention group until delivery.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","Cervical pessary","Placement of a cervical pessary (Arabin pessary) by an experienced gynecologist between 20 and 30 weeks of gestation in pregnant women with placenta previa or a low-lying placenta. Pessary position is monitored by ultrasound, preferably transvaginal ultrasound, at regular 4-week intervals until delivery. The pessary is removed at the onset of labor, before planned cesarean delivery, or earlier if clinically indicated because of complications such as infection or intolerance.",[9],[26],{"name":27,"affiliation":28,"role":29},"Ioannis Kyvernitakis, Prof. Dr.","Asklepios Klinik Barmbek","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","+49 40 18 18-828370","i.kyvernitakis@asklepios.com",{"name":36,"role":32,"phone":37,"phoneExt":18,"email":38},"Antonia Schenzler","+49 151 20 11 49 06","antonia@wampf.de",[40],{"facility":28,"status":18,"city":41,"state":18,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Hamburg-Nord","22307","Germany","DE",{"type":46,"coordinates":47},"Point",[48,49],9.984,53.58935,{"lat":49,"lon":48},[52],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},{"type":29,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Prof. Ioannis Kyvernitakis","Head of Section, Specialist in Gynecology and Obstetrics, specializing in Special Obstetrics and Perinatal Medicine","100643938","effect-of-a-cervical-pessary-on-the-rate-of-bleeding-in-placenta-praevia-100643938",false,"NCT07667777","Effect of a Cervical Pessary on the Rate of Bleeding in Placenta Praevia","Prospective, Randomised, Multicentre Study to Investigate the Effect of a Cervical Pessary on the Rate of Bleeding in Patients With Placenta Praevia","Inclusion Criteria:\n\n* Age 18 to 45 years\n* Singleton pregnancy\n* Ultrasound-confirmed placenta previa (total or marginal) diagnosed between 20 and 30 weeks of gestation\n* Or low-lying placenta with placental edge less than 20 mm from the internal os\n* Written informed consent provided\n\nExclusion Criteria:\n\n* Multiple pregnancy\n* Fetal malformations or chromosomal abnormalities detected by ultrasound\n* Uterine malformations\n* Silicone allergy\n* Cervical dilation\n* Cervical or vaginal infection\n* Cervical cancer\n* Cervical tears, cervical scarring, or ectopic cervical tissue\n* Preterm prelabor rupture of membranes\n* Regular uterine contractions\n* Cerclage in place\n* Pessary already in place\n* Active bleeding\n* Genital prolapse grade III or IV","FEMALE","18 Years","45 Years",{"count":67,"type":68},190,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study evaluates whether use of a cervical pessary can reduce vaginal bleeding and prolong pregnancy in women with placenta previa or a low-lying placenta. Placenta previa is a condition in which the placenta covers or lies close to the cervix and may cause serious bleeding, preterm birth, and complications for both the pregnant woman and the baby.\n\nIn this prospective, randomized, multicenter study, eligible women with singleton pregnancies and ultrasound-confirmed placenta previa or low-lying placenta between 20 and 30 weeks of gestation will be assigned either to treatment with an Arabin cervical pessary or to standard care without a pessary. The study will compare bleeding-related outcomes and pregnancy duration between the two groups.\n\nThe study is designed to determine whether a cervical pessary is a safe and effective intervention for reducing bleeding-related complications and prolonging gestation in this high-risk pregnancy population.",[74],"Placenta Previa","NOT_YET_RECRUITING","2026-06-19",{"date":78,"type":79},"2026-06-25","ACTUAL",{"date":81,"type":68},"2026-06",{"date":83,"type":68},"2027-07",{"name":5,"class":6},1]