[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600923":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":76,"collaborators":26,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":26,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":108,"whyStopped":26,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MPK","EXPERIMENTAL","Subjects will be fitted with the College Park ICON MPK and permitted to accommodate for 2 months prior to data collection.",[13],"Other: College Park ICON",{"label":15,"type":16,"description":17,"interventionNames":18},"NMPK","ACTIVE_COMPARATOR","Subjects will initially be evaluated walking on their conventional NMPK as a baseline prior to being fitted with the MPK.",[19],"Other: Conventional NMPK",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"OTHER","College Park ICON","Subjects will be fitted and trained on the College Park ICON MPK. An accommodation period of 2 months will be provided prior to evaluation with the knee joint.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Conventional NMPK","Subjects will be tested walking with their conventional, mechanical prosthetic knee prior to being fitted with the MPK.",[15],[32],{"name":33,"affiliation":34,"role":35},"Steven A Gard, PhD","Jesse Brown VA Medical Center, Chicago, IL","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Rebecca Stine, MS","CONTACT","(312) 503-5726","rebecca.stine@va.gov",{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},"(312) 503-5718","steven.gard@va.gov",[46,63],{"facility":34,"status":26,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Chicago","Illinois","60612","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-87.65005,41.85003,{"lat":56,"lon":55},[59,61,62],{"name":38,"role":39,"phone":60,"phoneExt":26,"email":41},"312-503-5726",{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"facility":64,"status":26,"city":65,"state":48,"zip":66,"country":50,"countryCode":51,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Edward Hines Jr. VA Hospital, Hines, IL","Hines","60141-3030",{"type":53,"coordinates":68},[69,70],-87.8395,41.85364,{"lat":70,"lon":69},[73,74],{"name":38,"role":39,"phone":60,"phoneExt":26,"email":41},{"name":33,"role":39,"phone":75,"phoneExt":26,"email":44},"3125035718",{"type":77,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100600923","effect-of-a-microprocessor-controlled-prosthetic-knee-joint-on-k2-level-ambulators-100600923",false,"NCT07103798","Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators","Does a Microprocessor-Controlled Prosthetic Knee Joint Improve Mobility and Quality of Life in K2-Level Veteran Ambulators?","MPK-K2","Inclusion Criteria:\n\n* Unilateral, transfemoral amputation (any etiology).\n* Age from 45-85 years.\n* Residual limb length classified as standard (i.e., medium) to long.\n* Prosthesis user for at least 1 year prior to enrolling in the study.\n* K2-level classification while using their NMPK.\n* Good sensation on their residual limb.\n* Good skin integrity upon visual inspection.\n* Presents with good socket fit based upon a standard assessment by the study prosthetist.\n\nExclusion Criteria:\n\n* Bilateral leg amputations.\n* Individuals with a knee disarticulation.","ALL","45 Years","85 Years",{"count":90,"type":91},20,"ESTIMATED","INTERVENTIONAL",[94],"NA","Microprocessor-controlled knees (MPKs) automatically adjust resistance or damping in the joint to improve swing- and\u002For stance-phase control as appropriate for the prosthesis user during gait. The purpose of this proposed investigation is to determine if there are substantial physical and psychological benefits to fitting lower functioning Veteran ambulators having transfemoral amputations with an MPK compared with a nonmicroprocessor-controlled knee (NMPK). Using a repeated-measures, cross-sectional experimental design, approximately 20 Veterans with unilateral, transfemoral amputations will be evaluated on two separate occasions at the Jesse Brown VA Medical Center or the Edward Hines, Jr. VA Hospital, first with their conventional NMPK and then again after a 2-month accommodation period with the College Park Icon MPK.",[97,98,99],"Transfemoral Amputation","Limb Loss","Limb Absence",[101,102,103,104,105,106,107],"amputation","limb loss","limb deficiency","transfemoral","above-knee","prosthesis","knee joint","NOT_YET_RECRUITING","2026-05-07",{"date":111,"type":112},"2026-05-08","ACTUAL",{"date":114,"type":91},"2026-07-01",{"date":116,"type":91},"2028-06-30",{"name":5,"class":6},2]