[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603640":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":62,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":99,"whyStopped":26,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental - Physiotherapy + Progressive Muscle Relaxation (PMR)","EXPERIMENTAL","Participants receive a 6-week standard physiotherapy program combined with Progressive Muscle Relaxation (PMR). Physiotherapy includes warm-up, weight-bearing training, balance training, gait training, and functional activities, delivered twice weekly. PMR sessions last 20 minutes, twice weekly, and involve systematic tensing\u002Frelaxing of major muscle groups, diaphragmatic breathing, and visualization techniques adapted for amputees.",[13],"Behavioral: Progressive Muscle Relaxation + Standard Physiotherapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Comparator - Standard Physiotherapy Only","ACTIVE_COMPARATOR","Participants receive the same 6-week standard physiotherapy program as the intervention group (warm-up, weight-bearing training, balance training, gait training, and functional activities, twice weekly) but without Progressive Muscle Relaxation.",[19],"Behavioral: Standard Physiotherapy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Progressive Muscle Relaxation + Standard Physiotherapy","Standard physiotherapy exercises plus PMR sessions. PMR is gradually transitioned from therapist-guided to self-directed practice across the 6 weeks.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard Physiotherapy","Participants receive a 6-week standard physiotherapy program delivered twice weekly. Sessions include warm-up, weight-bearing training, balance exercises, gait training, and functional activities. The protocol focuses on improving mobility, weight-bearing capacity, balance, and functional independence. No Progressive Muscle Relaxation or additional behavioral techniques are included.",[15],[32],{"name":33,"affiliation":34,"role":35},"Mosab Aldabbas, PhD","Al-Azhar University, Gaza Strip","STUDY_CHAIR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Marah Nayef Radi, MSc","CONTACT","+972597235445","m.radi@hi.org",{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},"+972562563022","mosab.m.aldabbas@gmail.com",[46],{"facility":47,"status":26,"city":48,"state":26,"zip":26,"country":49,"countryCode":26,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Artificial Limb & Polio Center (ALPC), Gaza","Gaza","Palestinian Territories",{"type":51,"coordinates":52},"Point",[53,54],34.46672,31.50161,{"lat":54,"lon":53},[57,58,59],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},{"name":60,"role":61,"phone":26,"phoneExt":26,"email":26},"Marah Radi, Master","PRINCIPAL_INVESTIGATOR",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Marah Radi","Master's Student, Faculty of Applied Medical Sciences, Al-Azhar University - Gaza","100603640","effect-of-adding-progressive-muscle-relaxation-to-physical-therapy-program-on-fatigue-mobility-and-stress-among-individuals-with-traumatic-lower-limb-amputation-in-the-gaza-strip-100603640",false,"NCT07139145","Effect of Adding Progressive Muscle Relaxation to Physical Therapy Program on Fatigue, Mobility and Stress Among Individuals With Traumatic Lower Limb Amputation in the Gaza Strip","Effect of Adding Progressive Muscle Relaxation to Physical Therapy Program on Fatigue, Mobility and Stress Among Traumatic Lower Limb Amputees in Gaza Strip","PMR-AMP","Inclusion Criteria:\n\n* Adults aged 18 to 59 years.\n* Unilateral traumatic trans-femoral\u002Ftranstibial amputation.\n* Post prosthetic fitting.\n\nExclusion Criteria:\n\n* Severe comorbidities (e.g., uncontrolled cardiovascular disease).\n* Severe cognitive impairment or mental illness.\n* Recent orthopaedic surgery (\\\u003C3 months)","ALL","18 Years","59 Years",{"count":78,"type":79},60,"ESTIMATED","INTERVENTIONAL",[82],"NA","Lower limb amputation is a life-altering condition with profound physical and psychological consequences, including fatigue, impaired mobility, stress, and asymmetrical weight-bearing. These challenges are particularly severe in conflict-affected settings like the Gaza Strip, where access to rehabilitation services is limited.\n\nThis study aims to evaluates the effect of adding Progressive Muscle Relaxation (PMR), a simple and cost-effective relaxation technique, to standard physical therapy on Fatigue, mobility, weightbearing distribution and stress outcomes among adults with unilateral traumatic lower limb amputation in Gaza.\n\nStudy design:\n\nRCT with 60 participants will be randomly assigned to either (1) a control group receiving standard physiotherapy or (2) an intervention group receiving standard physiotherapy plus PMR.\n\nOutcomes will be measured using validated instruments: Fatigue Severity Scale (FSS), 2-Minute Walk Test (2MWT), Perceived Stress Scale (PSS-10), and dual bathroom scale method for weight-bearing distribution. Assessments will be conducted at baseline, post-intervention (6 weeks), and follow-up (8 weeks).\n\nThe study aims to determine whether integrating PMR into rehabilitation improves fatigue reduction, functional mobility, stress management, and weight-bearing symmetry compared to physiotherapy alone. Findings will contribute to evidence-based rehabilitation strategies for amputees in low-resource, high-stress environments.",[85,86,87,88],"Traumatic Lower Limb Amputation","Fatigue","Mobility Impairment","Psychological Stress",[90,91,92,86,93,94,95,96,97,98],"Progressive Muscle Relaxation (PMR)","Physiotherapy","Rehabilitation","Mobility","Stress","Weight-Bearing Symmetry","Gaza Strip","Amputees","Randomized Controlled Trial (RCT)","NOT_YET_RECRUITING","2025-08-17",{"date":102,"type":103},"2025-08-24","ACTUAL",{"date":105,"type":79},"2025-09-15",{"date":107,"type":79},"2026-02-26",{"name":64,"class":6},1]