[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608390":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":41,"locations":48,"responsibleParty":62,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":26,"overallStatus":84,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Cairo University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"TENS + Mediterranean Diet","EXPERIMENTAL","This group will consist of 25 patients, who will receive TENS treatment at T6 dermatome for 30 minutes, 3 times per week for 12 weeks, in addition to following Mediterranean diet for 12 weeks.",[13,14],"Device: Transcutaneous electrical stimulation (TENS)","Other: Mediterranean Diet",{"label":16,"type":17,"description":18,"interventionNames":19},"Mediterranean Diet","ACTIVE_COMPARATOR","This group will consist of 25 patients, who will follow Mediterranean diet only for 12 weeks.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Transcutaneous electrical stimulation (TENS)","The negative\u002Factive pad surface electrode will be applied at the T6 dermatome on the abdomen (is located at the left upper quadrant of the abdomen, 2 cm below the ribcage at the left midclavicular line) for stimulation and the passive\u002Fpositive electrode will be applied on the left T6 costovertebral junction to complete the circuit.\n\n* The specific parameters of TENS will be burst mode, 2.0 Hz frequency, and 300 micro-seconds width\n* The patients will receive 3 times 30 min session each week for a period of consecutive 12 weeks.\n* The intensity of TENS will be gradually increased from 0 mA till the subject felt a comfortable tingling sensation beneath the electrode without any muscle contraction and pain.",[9],null,{"type":6,"name":16,"description":28,"armGroupLabels":29,"otherNames":26},"The recommended composition of Mediterranean diet regimen: is characterized by a high intake of plant foods, fruits, vegetables, breads and other cereals (traditionally minimally refined), potatoes, beans, nuts and seeds; minimally processed, fresh fruits as a typical dessert, with sweets containing sugars or honey a few times per week; .a high intake of olive oil (especially virgin and extra-virgin olive oil) as the main source of fat; a moderate intake of dairy products (mostly as cheese and yoghurt); zero to four eggs per week; low to moderate amounts of fish and poultry; low amounts of red meat. The diet plan included generally 50% carbohydrates (from vegetables, fruits, legumes, and whole grains), 35% fats (from healthy oils, nuts, seeds, and fish), and 15% protein (from legumes, fish, nuts, dairy, poultry, and eggs).",[16,9],[31,35,39],{"name":32,"affiliation":33,"role":34},"Nesreen Ghareeb El-Nahas, PhD","Professor, Cairo university","STUDY_CHAIR",{"name":36,"affiliation":37,"role":38},"Salma Ibrahim AL Ghitany, PhD","Lecturer, Cairo university","STUDY_DIRECTOR",{"name":40,"affiliation":33,"role":38},"Shawky Abdelhamid Fouad Abdel Gawad",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":26,"email":46},"Doaa Anwar Mohamed Ali, B.Sc","CONTACT","+20 100 310 8951","dr.doaanwar@hotmail.com",{"name":36,"role":44,"phone":26,"phoneExt":26,"email":26},[49],{"facility":50,"status":26,"city":51,"state":26,"zip":26,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Internal Medicine Hospital Cairo University","Giza","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],31.20861,30.00944,{"lat":58,"lon":57},[61],{"name":43,"role":44,"phone":45,"phoneExt":26,"email":46},{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Doaa Anwar Mohamed","Principal Investigator","100608390","effect-of-adding-tens-to-mediterranean-diet-on-appetite-and-liver-enzymes-in-nonalcoholic-fatty-liver-patients-100608390",false,"NCT07200934","Effect of Adding TENS to Mediterranean Diet on Appetite and Liver Enzymes in Nonalcoholic Fatty Liver Patients","Inclusion Criteria:\n\n* The age will range from 35-45 years old.\n* BMI (Body Mass Index 30-34.9 kg\u002Fm2.)\n* With fatty liver infiltration confirmed by abdominal ultrasound\n* Elevated of liver enzymes as a primary marker\n* All patients are psychologically stable.\n\nExclusion Criteria:\n\n* History of cardiovascular or respiratory disease.\n* If any known endocrine diseases e.g. Hypothyroidism (which elevates liver enzymes and effects on appetite)\n* Any acute or chronic illness causing elevated liver enzymes other than fatty liver e.g. Hepatitis b, Hepatitis c\n* Any neurological illness or impairment can effect on sensation\n* Patients associated with infections, mental or malignant conditions.\n* Patients who have undergone any gastric surgery e.g. Bariatric surgery\n* Taking dietary supplement for weight reduction.\n* Patients who participating in any other exercise program.","MALE","35 Years","45 Years",{"count":76,"type":77},50,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study aims to identify the effect of adding TENS to the Mediterranean diet on appetite and liver enzymes in Nonalcoholic fatty liver patients.",[83],"Nonalcoholic Fatty Liver","NOT_YET_RECRUITING","2025-09-23",{"date":87,"type":88},"2025-10-01","ACTUAL",{"date":90,"type":77},"2025-09-30",{"date":92,"type":77},"2026-01-14",{"name":5,"class":6},1]