[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598736":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":24,"responsibleParty":34,"collaborators":24,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":24,"eligibilityCriteria":43,"healthyVolunteers":39,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":24,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":63,"whyStopped":24,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":24},{"fullName":5,"class":6},"Federal University of Piaui","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Proximal\u002Fdistal protocol","EXPERIMENTAL","The experimental group will receive a proximal\u002Fdistal exercise program (trunk, hip, knee and ankle).",[13],"Other: Proximal\u002Fdistal protocol",{"label":15,"type":16,"description":17,"interventionNames":18},"Distal protocol","ACTIVE_COMPARATOR","The control group will receive a distal exercise program (ankle and foot) available in the literature and previously tested.",[19],"Other: Distal protocol",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"The experimental group will receive a proximal\u002Fdistal exercise program (trunk, hip, knee and ankle) consisting of four stages: warm-up, strengthening, sensorimotor training and relaxation.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"The control group will receive a distal exercise program available in the literature and previously tested. This will contain warm-up exercises, intrinsic foot muscle strengthening, extrinsic foot-ankle muscle strengthening, and functional exercises.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Vinicius Saura Cardoso","CONTACT","+55 86 99984-2919","vscfisio@ufdpar.edu.br",{"type":35,"investigatorFullName":30,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100598736","effect-of-an-exercise-program-on-clinical-aspects-of-people-with-diabetic-peripheral-neuropathy-100598736",false,"NCT07075367","Effect of an Exercise Program on Clinical Aspects of People With Diabetic Peripheral Neuropathy","Effect of a Trunk, Hip, Knee and Ankle Exercise Program on Clinical Aspects of People With Diabetic Peripheral Neuropathy: a Randomized Clinical Trial","Inclusion Criteria:\n\n* Adult individuals aged between 45 and 75 years, male or female, diagnosed with DM2;\n* DPN diagnosis based on vibration sensitivity tests assessed by a 128 Hz tuning fork and tactile sensitivity measured by a 10 g monofilament\n* Sedentary or irregularly active individuals (level A) according to the Physical Activity Level Classification - IPAQ\n* Score of at least 5 points on the Functional Independence Measure (FIM), i.e., requires supervision, but without physical contact\n* Absence of diabetic foot ulcer (DFU) for at least one month\n* No amputation or at most amputation of fingers, except for the hallux\n\nExclusion Criteria:\n\n* Individuals involved in physical training programs simultaneously with the intervention\n* History of surgical intervention in the lower limbs or spine\n* Use of walking assistance devices\n* Diagnosis of severe cardiovascular disorder\n* Diagnosis of other neurological impairments in addition to DPN\n* Presence of dementia or inability to provide consistent information\n* Severe retinopathy","ALL","45 Years","75 Years",{"count":48,"type":49},64,"ESTIMATED","INTERVENTIONAL",[52],"NA","Diabetic Peripheral Neuropathy (DPN) is one of the most prevalent and debilitating complications of type 2 diabetes mellitus (DM2), especially affecting the distal region of the lower limbs. Such changes affect clinical aspects, such as quality of life. Several pieces of evidence point to therapeutic exercises as an effective way to minimize these deficits. This is a single-blind randomized clinical trial in which participants will be randomly assigned to two groups. The stipulated sample size was 64 participants. The experimental group will receive a distal\u002Fproximal exercise program and the control group will receive a distal exercise program available in the literature and previously tested. The intervention will last 12 weeks and will take place twice a week, with an average time of 50 minutes. Neuropathic symptoms will be considered primary outcomes. The secondary outcomes evaluated will be: capillary blood glucose, Mini-BESTest, Falls Efficacy Scale (FES), EQ-5D and HADS (depression and anxiety). This study was approved by the local research ethics committee (Opinion 6.802.243), conducted in accordance with the Declaration of Helsinki and in accordance with the CONSORT guidelines.",[55],"Diabetic Peripheral Neuropathy",[57,58,59,60,61,62],"Diabetic peripheral neuropathy","Exercise therapy","Neuropathy symptoms","Quality of life","Depression","Anxiety","NOT_YET_RECRUITING","2025-10-01",{"date":66,"type":67},"2025-10-02","ACTUAL",{"date":69,"type":49},"2026-01-10",{"date":71,"type":49},"2028-01",{"name":5,"class":6}]