[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536195":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":30,"locations":41,"responsibleParty":67,"collaborators":35,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":35,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":43,"whyStopped":35,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"ART Fertility Clinics LLC","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: antioxidants-enriched culture medium (Gx)","ACTIVE_COMPARATOR","Blastocyst exposed to antioxidants-enriched culture medium (Gx) in continuous culture conditions, without refreshment on day 3. A refreshment of the media will be done on D5 in both groups.",[13],"Drug: antioxidants-enriched culture medium (Gx)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2: Global total one step media (GT)","Blastocyst exposed to Global total one step media (GT) in continuous culture conditions, without refreshment on day 3. A refreshment of the media will be done on D5 in both groups.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","antioxidants-enriched culture medium (Gx)","Blastocyst will be in continuous culture conditions (parallel antioxidants-enriched culture medium (Gx) and Global total one step media (GT) without refreshment on day 3. A refreshment of the media will be done on D5 in both groups.",[9,15],[25],"Global total one step media (GT)",[27],{"name":28,"affiliation":5,"role":29},"Barbara Lawrenz","STUDY_DIRECTOR",[31,37],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Daniela Nogueira","CONTACT","+971504374961",null,"daniela.nogueira@artfertilityclinics.com",{"name":38,"role":33,"phone":39,"phoneExt":35,"email":40},"Jonalyn DV Edades","+971526408688","jonalyn.ededas@artfertilityclinics.com",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Abu Dhabi","Abu Dhabi Emirate","60202","United Arab Emirates","AE",{"type":50,"coordinates":51},"Point",[52,53],54.39696,24.45118,{"lat":53,"lon":52},[56,61,65],{"name":57,"role":33,"phone":58,"phoneExt":59,"email":60},"Barbara Lawrenz, PhD","+97102 652 8000","1108","barbara.lawrenz@artfertilityclinics.com",{"name":62,"role":33,"phone":58,"phoneExt":63,"email":64},"Jonalyn Edades","1106","jonalyn.edades@artfertilityclinics.com",{"name":57,"role":66,"phone":35,"phoneExt":35,"email":35},"PRINCIPAL_INVESTIGATOR",{"type":68,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100536195","effect-of-antioxydant-enriched-media-on-blastocyst-euploidy-rates-100536195",false,"NCT06261671","Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.","Antioxidants-enriched Single-step vs Global Total Single-step Embryo Culture Media: Effect on Blastocyst Euploidy Rates.","GX","Inclusion Criteria:\n\n* Patients undergoing assisted reproductive technology cycles when ICSI is indicated.\n* Patients when Iin vitto fertilization (IVF) is also performed will be included as far as there are enough oocytes for ICSI randomization. However, IVF oocytes will not be used for the study.\n* Maternal age 18-43 years old.\n* PGT-A cycles with only trophectoderm biopsies on day 5\u002F6\u002F7.\n* Patients with more than 6 COCs expected for ICSI.\n* Body mass index \\\u003C35.\n* Fresh and frozen ejaculated sperm.\n\nExclusion Criteria:\n\n* PGT-M cycles\n* Fresh and frozen testicular sperm.",true,"ALL","18 Years","43 Years",{"count":82,"type":83},500,"ESTIMATED","INTERVENTIONAL",[86],"NA","One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in a prospective randomized trial using sibling oocytes.",[89,90],"Infertility","In Vitro Fertilization",[92,93,94,95,96,97],"Intracytoplasmic sperm injection","Pre - implanttaion genetic diagnosis for aneuploidy","Antioxydante","Culture media","Embryo development","Euploidy","2025-02-20",{"date":100,"type":101},"2025-02-21","ACTUAL",{"date":103,"type":101},"2024-02-01",{"date":105,"type":83},"2025-12-31",{"name":5,"class":6},1]