[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551264":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":30,"locations":36,"responsibleParty":50,"collaborators":11,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":11,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Suez Canal University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"No apical patency","SHAM_COMPARATOR",null,[13,14],"Procedure: Non-corticosteroid injection","Drug: Corticosteroid injection",{"label":16,"type":17,"description":11,"interventionNames":18},"Apical patency","ACTIVE_COMPARATOR",[13,14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Non-corticosteroid injection","no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.",[16,9],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"DRUG","Corticosteroid injection","infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.",[16,9],[31],{"name":32,"role":33,"phone":34,"phoneExt":11,"email":35},"Mustafa Sultan","CONTACT","+201111506890","sultan_mustafa@hotmail.com",[37],{"facility":5,"status":38,"city":39,"state":11,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Ismailia","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],32.27225,30.60427,{"lat":46,"lon":45},[49],{"name":32,"role":33,"phone":34,"phoneExt":11,"email":35},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Mustafa M. Sultan","Teaching assistant","100551264","effect-of-apical-patency-and-local-corticosteroid-on-pain-and-neuropeptides-release-in-patients-with-symptomatic-irreversible-pulpitis-a-randomized-clinical-trial-100551264",false,"NCT06457828","Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Symptomatic acute irreversible pulpitis in molar teeth.\n* Normal periapical condition including periapical radiography with minimal widening of periodontal ligament.\n* Normal probing depth.\n* No medical condition.\n* No contraindication for administration of corticosteroids and local anesthesia.\n\nExclusion Criteria:\n\n* Facial or oral paresthesia.\n* Pregnancy \\& breastfeeding.\n* Unrestorable tooth.\n* Marginal periodontal disease.\n* Presence of a crown on the tooth involved.\n* Over instrumentation during root canal treatment.\n* Long-term use of corticosteroids.\n* False-positive cases of sensibility test with necrosis discovered after gaining access to the tooth.\n* Cases requiring intrapulpal injection to promote anesthesia.",true,"ALL","21 Years","60 Years",{"count":65,"type":66},40,"ESTIMATED","INTERVENTIONAL",[69],"NA","The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is:\n\n• How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not.\n\nResearchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.",[72,73],"Postoperative Pain","Symptomatic Irreversible Pulpitis",[75,72,76],"Pulpitis","VAS","2024-06-08",{"date":79,"type":80},"2024-06-13","ACTUAL",{"date":82,"type":80},"2021-02-01",{"date":84,"type":66},"2024-09",{"name":5,"class":6},1]