[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604138":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":54,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Samsun University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ITM",null,"Patients undergoing elective cesarean delivery under spinal anesthesia with 100 µg intrathecal morphine (ITM) as part of standard care. No additional regional block will be performed. Postoperative analgesia will be maintained with intravenous patient-controlled analgesia (IV PCA) using morphine, along with multimodal analgesia.Approximately 75 participants will be enrolled in this group",[13],"Other: Spinal Anesthesia with Intrathecal Morphine Only",{"label":15,"type":10,"description":16,"interventionNames":17},"ITM + TAP","Patients undergoing elective cesarean delivery under spinal anesthesia with 100 µg intrathecal morphine (ITM) as part of standard care, plus bilateral ultrasound-guided transversus abdominis plane (TAP) block performed at the end of surgery. Postoperative analgesia will be maintained with intravenous patient-controlled analgesia (IV PCA) using morphine, along with multimodal analgesia.Approximately 75 participants will be enrolled in this group",[18],"Other: Spinal Anesthesia with Intrathecal Morphine plus Bilateral TAP Block",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"Spinal Anesthesia with Intrathecal Morphine Only","Elective cesarean delivery performed under spinal anesthesia with the addition of 100 micrograms intrathecal morphine (ITM) as part of standard clinical care. No additional regional block is performed. Postoperative analgesia is maintained with intravenous patient-controlled analgesia (IV PCA) morphine and multimodal analgesia, including scheduled paracetamol and NSAIDs as per institutional protocol.",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Spinal Anesthesia with Intrathecal Morphine plus Bilateral TAP Block","Elective cesarean delivery performed under spinal anesthesia with the addition of 100 micrograms intrathecal morphine (ITM) as part of standard clinical care, plus bilateral ultrasound-guided transversus abdominis plane (TAP) block performed at the end of surgery. The TAP block will be performed in-plane with a high-frequency linear probe, using 0.25% bupivacaine, 20 mL per side, injected between the internal oblique and transversus abdominis muscles. Postoperative analgesia will be maintained with intravenous patient-controlled analgesia (IV PCA) morphine and multimodal analgesia, including scheduled paracetamol and NSAIDs.",[15],[29],{"name":30,"affiliation":31,"role":32},"Mehmet Gökhan Taflan, MD","Samsun Education and Research Hospital","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","+905352114070","drmehmettaflan@gmail.com",[39],{"facility":40,"status":41,"city":42,"state":42,"zip":43,"country":44,"countryCode":10,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Samsun University Training and Research Hospital","RECRUITING","Samsun","55090","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],36.3361,41.27976,{"lat":49,"lon":48},[52],{"name":30,"role":35,"phone":53,"phoneExt":10,"email":37},"+9005352114070",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","MEHMET GÖKHAN TAFLAN","Principal Investigator, Specialist in Anesthesiology","100604138","effect-of-bilateral-ultrasound-guided-tap-block-on-quality-of-recovery-in-cesarean-delivery-patients-receiving-intrathecal-morphine-100604138",false,"NCT07145619","Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine","Effect of Bilateral Ultrasound-Guided Transversus Abdominis Plane Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine: A Prospective Observational Cohort Study","QoR-TAP","Inclusion Criteria:\n\n* Female patients aged 18-45 years\n* Singleton pregnancy\n* ASA physical status II-III\n* Scheduled elective lower segment cesarean delivery under spinal anesthesia with intrathecal morphine (ITM) as standard care\n* Able to understand study procedures, provide written informed consent, and reliably use IV PCA\n* Able to complete ObsQoR-10-T assessments (with trained assistance if needed)\n\nExclusion Criteria:\n\n* Contraindication to spinal anesthesia or TAP block (e.g., infection at injection site, coagulopathy, allergy to local anesthetics)\n* Chronic opioid use or opioid\u002Falfa-2 agonist intolerance\n* Severe preeclampsia, HELLP syndrome, significant hepatic or renal impairment\n* Urgent or emergent cesarean section (Category 1)\n* Cognitive impairment or communication difficulty preventing accurate assessment\n* Prior major abdominal surgery (other than previous cesarean delivery)\n* Body mass index (BMI) \\> 40 kg\u002Fm²\n* Major psychiatric illness (e.g., major depressive disorder, generalized anxiety disorder, psychosis) that may affect pain perception or quality of recovery","FEMALE","18 Years","45 Years",{"count":70,"type":71},150,"ESTIMATED","OBSERVATIONAL","This prospective, assessor-blinded observational cohort study will investigate the effect of adding bilateral ultrasound-guided transversus abdominis plane (TAP) block to standard intrathecal morphine (ITM) analgesia on the quality of recovery in women undergoing elective cesarean delivery under spinal anesthesia. All participants will receive ITM as part of routine spinal anesthesia. The TAP group will receive an additional bilateral ultrasound-guided TAP block at the end of surgery, while the control group will not receive any additional block. Both groups will receive standardized postoperative analgesia with intravenous patient-controlled analgesia (IV PCA). The primary outcome is the quality of recovery at 24 hours postoperatively, measured using the validated Obstetric Quality of Recovery-10 (ObsQoR-10) questionnaire. Secondary outcomes include Numerical Rating Scale (NRS) pain scores, time to first breastfeeding, time to mobilization, time to hospital discharge, and total opioid consumption in the first 24 hours after surgery. Outcome assessors will be blinded to group allocation. The study aims to determine whether TAP block enhances functional recovery, reduces pain, and decreases analgesic requirements when used alongside ITM in cesarean delivery patients.",[75,76,77],"Postoperative Pain Management","Obstetric Anesthesia","Recovery From Anesthesia",[79,80,81,82,83,84,85],"Cesarean delivery","Spinal anesthesia","Intrathecal morphine","Transversus abdominis plane block","Postoperative pain","Obstetric anesthesia","Quality of recovery","2026-06-13",{"date":88,"type":89},"2026-06-16","ACTUAL",{"date":91,"type":89},"2025-09-01",{"date":93,"type":71},"2026-07-30",{"name":56,"class":6},1]