[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580821":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":31,"collaborators":26,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":26,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":26,"enrollmentInfo":44,"targetDuration":26,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":26,"overallStatus":53,"whyStopped":26,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":26},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention arm","EXPERIMENTAL","In this arm principal investigator will preform coronally advanced flap with De-epithelized free gingival graft then will inject Botulinum toxin-A in Mentalis muscle after suturing",[13],"Procedure: Botulinum toxin-A injection",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","ACTIVE_COMPARATOR","In this arm no injection will be applied only coronally advanced flap with De-epithelized free gingival graft alone",[19],"Procedure: Coronally advanced flap",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Botulinum toxin-A injection","Botulinum toxin-A Injection Mentalis muscle in lower anterior teeth",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Coronally advanced flap","Coronally Advanced Flap andDe-epithelized Free Gingival Graft",[15],{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Mayar Mostafa Tawfik Ali","Principal investigator","100580821","effect-of-botulinum-toxin-a-injection-in-treatment-of-recession-rt1-and-rt2-100580821",false,"NCT06842290","Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2","Effect of Botulinum Toxin -A Injection in Mentalis Muscle with Coronally Advanced Flap and De-epithelized Free Gingival Graft in Treatment of RT1 , RT2 Gingival Recession _Randomized Control Trial","Inclusion Criteria:\n\n* Single or multiple RT1, RT2 GR patient\n* patients ≥18 years\n* systemically healthy, full mouth plaque score, full mouth bleeding score ≤ 15% after phase I therapy\n* clinical indication and\u002For patient request for recession coverage\n* well motivated patients, maintaining oral hygiene throughout study\n\nExclusion Criteria:\n\n* Pregnant or lactating women\n* Smokers' patients\n* Teeth with cervical restorations\u002Fabrasion.\n* Patients had a systemic condition affect blood components and healing","ALL","18 Years",{"count":45,"type":46},28,"ESTIMATED","INTERVENTIONAL",[49],"NA","The goal of this study type: clinical trial\\] is to learn the effect of Botulinum Toxin \\_A injection in treatment of RT1andRT2 Gingival recession in lower anterior teeth .\n\nPrimary outcome is keratinzed tissue width. Researchers will compare Coronally Advanced flap with De-epithelized free gingival graft and Botulinum toxin-A injection in Mentalis muscle with coronally advanced flap with De-epithelized free gingival graft alone .\n\nThe outcome will be measured at baseline, after 3 months and after 6 mobths \\_medical history\n\n* 3 mm horizontal incisions, then two vertical incisions\n* deepitheliztion of anatomical papillae\n* superficial and deep incisions\n* harvesting DFGG\n* Suturing\n* BOTOX injection",[52],"Gingival Recession","NOT_YET_RECRUITING","2025-02-23",{"date":56,"type":57},"2025-02-25","ACTUAL",{"date":59,"type":46},"2025-04-04",{"date":61,"type":46},"2026-10-16",{"name":5,"class":6}]