[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645064":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":50,"locations":59,"responsibleParty":77,"collaborators":36,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":36,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":36,"overallStatus":62,"whyStopped":36,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"control","ACTIVE_COMPARATOR","Surgical Depigmentation Alone",[13],"Procedure: surgical depigmentation",{"label":15,"type":16,"description":17,"interventionNames":18},"test I","EXPERIMENTAL","Surgical Depigmentation + CoQ10",[13,19],"Dietary Supplement: Coenzyme Q10",{"label":21,"type":16,"description":22,"interventionNames":23},"Test II","Surgical Depigmentation + Vitamin C",[13,24],"Dietary Supplement: Vitamin C",{"label":26,"type":16,"description":27,"interventionNames":28},"Test III","Surgical Depigmentation + CoQ10 + Vitamin C",[13,29],"Dietary Supplement: Surgical Gingival Depigmentation Coenzyme Q10 Vitamin C",[31,37,42,46],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"PROCEDURE","surgical depigmentation","Surgical gingival depigmentation performed using the conventional scalpel technique. The pigmented gingival epithelium is surgically removed under local anesthesia to eliminate melanin pigmentation and improve gingival esthetics.",[21,26,9,15],null,{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":36},"DIETARY_SUPPLEMENT","Coenzyme Q10","Coenzyme Q10 administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival depigmentation.",[15],{"type":38,"name":43,"description":44,"armGroupLabels":45,"otherNames":36},"Vitamin C","Vitamin C administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival depigmentation.",[21],{"type":38,"name":47,"description":48,"armGroupLabels":49,"otherNames":36},"Surgical Gingival Depigmentation Coenzyme Q10 Vitamin C","Coenzyme Q10 and vitamin c administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival repigmentation.",[26],[51,56],{"name":52,"role":53,"phone":54,"phoneExt":36,"email":55},"nora abdelgawad associate professor, phd","CONTACT","+201019407891","noramohamed.26@azhar.edu.eg",{"name":57,"role":53,"phone":58,"phoneExt":36,"email":36},"nora abdelgawad abdelgawad, phd","021019407891",[60],{"facility":61,"status":62,"city":63,"state":36,"zip":36,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Faculty of dental medicine for girls? ALAZHAR University, Cairo, egypt","RECRUITING","Nāşir","Egypt","EG",{"type":67,"coordinates":68},"Point",[69,70],33.03449,24.54246,{"lat":70,"lon":69},[73],{"name":74,"role":53,"phone":75,"phoneExt":36,"email":76},"Nora Abdelgawad Associate professor, Phd","+×01019407891","Noramohamed.26@azhar.edu.eg",{"type":78,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Nora Abdelgawad Mohamed","associate professor of oral medicine and periodontology","100645064","effect-of-co-enzyme-q10-and-vitamin-c-alone-or-in-combination-after-a-surgical-gingival-depigmentation-100645064",false,"NCT07677826","Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation","Ffect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation a Randomized Clinical Study","Effect of Coe","Inclusion Criteria:\n\n* Systemically healthy patient of both genders aged from 18-45 years.\n* Presence of bilateral physiologic gingival pigmentation in the anterior maxillary or mandibular region DOPI grades III-IV only.\n* Good oral hygiene.\n* Thick gingival phenotype.\n\nExclusion Criteria:\n\n* Patient clinically diagnosed with periodontitis.\n* Pregnant or lactating females.\n* Patient with previous treatment of gingival hyperpigmentation.\n* History of hypersensitivity to any study material.\n* Patients who are active or previous smokers.",true,"ALL","18 Years","45 Years",{"count":94,"type":95},20,"ESTIMATED","INTERVENTIONAL",[98],"NA","This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.",[101,102],"Depigmentation Treatment","Depigmentation","2026-06-29",{"date":105,"type":106},"2026-07-01","ACTUAL",{"date":108,"type":106},"2026-03-02",{"date":110,"type":95},"2026-12-20",{"name":5,"class":6},1]