[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100540256":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":54,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":25,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Hospital Clinic of Barcelona","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Conservative treatment","ACTIVE_COMPARATOR","Subjects allocated to this arm will receive hygienic and dietary measures counselling",[13],"Other: Hygienic and dietary advice",{"label":15,"type":16,"description":17,"interventionNames":18},"CPAP treatment","EXPERIMENTAL","Subjects allocated to this arm will receive treatment with continuous positive airway pressure (CPAP)",[19],"Device: CPAP treatment",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Subjects allocated to this arm will receive continuous positive airway pressure (CPAP)",[15],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Hygienic and dietary advice","Subjects allocated to this arm will receive hygienic and dietary counselling",[9],[31],{"name":32,"affiliation":33,"role":34},"Mireia Dalmases, MD","Hospital Clinic","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","+34932275746","mdalmase@clinic.cat",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":45,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":25},"Hospital Clinic Barcelona","RECRUITING","Barcelona","Spain","08036","ES",{"type":49,"coordinates":50},"Point",[51,52],2.15899,41.38879,{"lat":52,"lon":51},{"type":34,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Mireia Dalmases","Principal investigator","100540256","effect-of-cpap-treatment-in-patients-with-severe-uncontrolled-asthma-the-asthma-sleep-trial-100540256",false,"NCT06314477","Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial","Effect of CPAP Treatment on Asthma Control in Patients With Severe Uncontrolled Asthma and Obstructive Sleep Apnea: The ASTHMA-SLEEP Study","Inclusion Criteria:\n\n* Age \\>18 years\n* Diagnosis of severe uncontrolled asthma according to the criteria of the Spanish Asthma Management Guide (GEMA) or the Global Initiative for Asthma (GINA) and no hospitalizations the month prior to inclusion in the study.\n* Apnea hypopnea rate greater than or equal to 15\u002Fhour\n* Punctuation in the Epworth Sleepiness Scale ≤10\n* Obtaining informed consent.\n\nExclusion Criteria:\n\n* Previous treatment with CPAP\n* Patient with central sleep apnea or Cheyne-Stokes respiration\n* Other sleep disorders: narcolepsy, restless leg syndrome, chronic insomnia,\n* Resistant hypertension\n* Active Smoking\n* Unstable comorbidities or medications may interfere with asthma control\n* Pregnancy\n* Any process that reduces life expectancy to \\\u003C1 year,\n* Any medical or social factor that may limit CPAP compliance","ALL","18 Years",{"count":67,"type":68},138,"ESTIMATED","INTERVENTIONAL",[71],"NA","The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)",[74,75],"Obstructive Sleep Apnea","Asthma","2025-12-04",{"date":78,"type":79},"2025-12-11","ACTUAL",{"date":81,"type":79},"2023-12-27",{"date":83,"type":68},"2026-12",{"name":5,"class":6},1]