[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621793":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":64,"collaborators":67,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":95,"overallStatus":49,"whyStopped":25,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Ginefiv","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standardized Mediterranean Diet Alone (Control)","ACTIVE_COMPARATOR","Participants will follow a standardized Mediterranean diet for a period of 12 weeks. Adherence to the dietary recommendations will be monitored using a self-administered compliance diary and scheduled follow-up phone calls.",[13],"Other: Standardized Mediterranean Diet",{"label":15,"type":16,"description":17,"interventionNames":18},"Gazpacho + Standardized Mediterranean Diet (Intervention)","EXPERIMENTAL","Participants assigned to the intervention arm will follow a standardized Mediterranean diet for 12 weeks and will additionally consume 330 mL of commercially available gazpacho once daily with a main meal. Adherence to the intervention will be monitored using a self-administered compliance diary and scheduled follow-up phone calls.",[13,19],"Dietary Supplement: Gazpacho",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Standardized Mediterranean Diet","Participants will follow a standardized Mediterranean diet for a period of 12 weeks. The dietary pattern emphasizes the consumption of vegetables, fruits, legumes, whole grains, olive oil as the main source of fat, moderate intake of fish and nuts, and limited intake of red and processed meats.",[15,9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"DIETARY_SUPPLEMENT","Gazpacho","Participants will consume 330 mL per day of commercially available gazpacho, taken once daily with a main meal, for a period of 12 weeks. The gazpacho will be consumed as part of the daily diet in addition to a standardized Mediterranean diet.",[15],[32],{"name":33,"affiliation":34,"role":35},"Pablo Martí Pastor, RD, RND","Ginefiv Madrid (IVIRMA Group)","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},"Pablo Martí Pastor, RN, RDN","CONTACT","+34 669975090","pablo.marti@ginefiv.com",{"name":43,"role":39,"phone":44,"phoneExt":25,"email":45},"Julio Gijón de la Santa, Senior Clinical Embryologist","636636799","julio.gijon@ginefiv.com",[47],{"facility":48,"status":49,"city":50,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"GINEFIV Madrid (IVIRMA Group)","RECRUITING","Madrid","28010","Spain","ES",{"type":55,"coordinates":56},"Point",[57,58],-3.70256,40.4165,{"lat":58,"lon":57},[61,62],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},{"name":43,"role":39,"phone":63,"phoneExt":25,"email":45},"+34 636636799",{"type":35,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Pablo Martí","Nurse and Dietitian-Nutritionist (Assisted Reproduction)",[68],{"name":69,"class":6},"Instituto Valenciano de Infertilidad, IVI VALENCIA","100621793","effect-of-daily-intake-of-gazpacho-on-semen-quality-and-oxidative-stress-100621793",false,"NCT07375238","Effect of Daily Intake of Gazpacho on Semen Quality and Oxidative Stress","Effect of Daily Intake of Gazpacho on Semen Quality and Oxidative Stress in Men With Altered Semen Parameters: A Randomized Controlled Study","G-OXSEM","Inclusion Criteria:\n\n* Men aged 18 to 45 years\n* Andrological profile including altered semen parameters such as oligozoospermia, asthenozoospermia and\u002For teratozoospermia (O±A±T)\n* No clinical indication for sperm DNA fragmentation testing or advanced sperm selection techniques\n* Willingness and ability to comply with the study protocol, including adherence to a standardized Mediterranean diet\n* Signed and dated written informed consent form\n\nExclusion Criteria:\n\n* Use of antioxidant supplements during the three months prior to study start.\n* Active smokers or men who have stopped smoking within the last three months.\n* Diagnosis of azoospermia, leucocytospermia or necrozoospermia.\n* Presence of severe systemic diseases or chronic conditions that could interfere with semen quality or adherence to the study.\n* Known allergy or intolerance to any ingredient of the gazpacho used in the study.\n* Any medical, psychological or social condition that, in the investigator's judgement, could compromise the subject's ability to participate fully or comply with the protocol requirements.\n* Simultaneous participation in another clinical study.","MALE","18 Years","45 Years",{"count":82,"type":83},80,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to learn whether drinking a daily serving of gazpacho can improve semen quality in men with reduced sperm quality. The study will also examine how this dietary intervention affects oxidative stress and whether it is well tolerated.\n\nThe main questions this study aims to answer are:\n\n* Does daily consumption of gazpacho improve semen quality in men with altered semen parameters?\n* Does this dietary intervention affect levels of oxidative stress in semen?\n* Is daily gazpacho intake feasible and well tolerated as part of a Mediterranean diet?\n\nResearchers will compare a Mediterranean diet plus daily gazpacho intake with a Mediterranean diet alone to determine whether adding gazpacho provides additional benefits for male reproductive health.\n\nParticipants will:\n\n* Follow a standardized Mediterranean diet for 12 weeks\n* Drink 330 mL of gazpacho every day or follow the diet without gazpacho\n* Provide semen samples at the start of the study and after 12 weeks\n* Complete a short diary to record adherence to the dietary intervention\n* Be followed for up to 18 months to record reproductive outcomes",[89,90,91,92,93,94],"Male Infertility","Oxidative Stress","Subfertility","Oligozoospermia","Asthenozoospermia","Teratozoospermia",[96,28,97,98,99,100,101,102],"Mediterranean diet","sperm quality","Male infertility","Altered semen parameters","oxidative stress","OxiSperm II","Randomized trial","2026-03-11",{"date":105,"type":106},"2026-03-13","ACTUAL",{"date":108,"type":106},"2026-03-02",{"date":110,"type":83},"2029-09-01",{"name":5,"class":6},1]