[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546373":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":42,"collaborators":10,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":57,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":23,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Beijing Friendship Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"DS Group",null,"Patients with degenerative spondylolisthesis Meyerding grade Ⅰ (slippage \\>3 mm but \\\u003C25%) will be identified as having lumbar spinal stenosis combined with degenerative spondylolisthesis and will be allocated to the DS group.",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-DS Group","Patients not with degenerative spondylolisthesis will be identified as having lumbar spinal stenosis only and will be allocated to the Non-DS group.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Xiang Li","CONTACT","+86 10 6313 9155","muzixiangxin2022@163.com",[22],{"facility":5,"status":23,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Beijing","Beijing Municipality","100050","China","CN",{"type":30,"coordinates":31},"Point",[32,33],116.39723,39.9075,{"lat":33,"lon":32},[36,40],{"name":37,"role":18,"phone":38,"phoneExt":10,"email":39},"Yue Li","+86 10 6313 9006","13661202501@163.com",{"name":17,"role":41,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":43,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100546373","effect-of-degenerative-spondylolisthesis-on-the-clinical-outcome-of-unilateral-biportal-endoscopy-for-lumbar-spinal-stenosis-study-protocol-100546373",false,"NCT06394089","Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol","Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: a Single-center, Prospective Cohort Trial Protocol","Inclusion Criteria:\n\n* Age range: 50-80 years\n* Diagnosis of LSS affecting 1-2 vertebral levels\n* Predominant manifestation of neurogenic intermittent claudication, with ineffective conservative treatment for at least 3 months\n* Presence of lumbar DS of less than grade II and absence of spine instability\n* Willingness to participate in the study and complete follow-up assessments.\n\nExclusion Criteria:\n\n* Diagnosis of isthmic lumbar spondylolisthesis or lumbar DS of grade ≥II\n* Evidence of instability at the affected vertebral level (intervertebral angle change \\> 15° and\u002For vertebral translation ≥ 4.5 mm in standing flexion-extension radiographs of the lumbar spine)\n* History of prior surgery at the affected vertebral level\n* Presence of scoliosis with a Cobb angle \\>20º\n* Presence of other conditions affecting the lumbar spine (infection, tumor, fracture, neurological diseases, and others)\n* Medical disorders that preclude surgical tolerance\n* Participation in other clinical research projects related to the treatment of lumbar spinal stenosis.","ALL","50 Years","80 Years",{"count":55,"type":56},150,"ESTIMATED","2 Years","OBSERVATIONAL","A single-center, prospective cohort trial aims to provide stronger evidence regarding the impact of degenerative spondylolisthesis on the clinical outcome of unilateral biportal endoscopy for lumbar spinal stenosis",[61,62],"Degenerative Spondylolisthesis","Lumbar Spinal Stenosis","2025-06-03",{"date":65,"type":66},"2025-06-06","ACTUAL",{"date":68,"type":66},"2024-03-01",{"date":70,"type":56},"2027-02-28",{"name":5,"class":6},1]