[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627299":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":34,"locations":39,"responsibleParty":55,"collaborators":18,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":18,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":18,"overallStatus":76,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"intervention group(suture needle insertion at 2.5 mm posterior to the cornea limbus)","EXPERIMENTAL","Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2.5mm post-limbal during surgery,and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively.",[13],"Procedure: YAMANE technique(Suture Needle Insertion at 2.5 mm Posterior to the Limbus)",{"label":15,"type":16,"description":17,"interventionNames":18},"compare group(suture needle insertion at 2 mm posterior to the cornea limbus)","NO_INTERVENTION","Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2mm post-limbal during surgery,and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","YAMANE technique(Suture Needle Insertion at 2.5 mm Posterior to the Limbus)","Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2.5mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively.",[9],[26,30],{"name":27,"affiliation":28,"role":29},"Danying Zheng","Guangdong Provincial Clinical ResearchCenter for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou, Guangdong","STUDY_CHAIR",{"name":31,"affiliation":32,"role":33},"Guangming Jin","Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou, Guangdong","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":18,"email":38},"CONTACT","+86 13560035613","jinguangming@gzzoc.com",[40],{"facility":41,"status":18,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science","Guangdong","Province","510060","China","CN",{"type":48,"coordinates":49},"Point",[50,51],129.33635,42.76832,{"lat":51,"lon":50},[54],{"name":31,"role":36,"phone":37,"phoneExt":18,"email":38},{"type":33,"investigatorFullName":31,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Associate Chief Physician, Cataract Department","100627299","effect-of-different-needle-insertion-positions-on-the-clinical-outcomes-of-yamane-technique-100627299",false,"NCT07446829","Effect of Different Needle Insertion Positions on the Clinical Outcomes of YAMANE Technique","Effect of Different Needle Insertion Positions on the Clinical Outcomes of YAMANE Technique for Intrascleral Intraocular Lens Fixation: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients aged 4-18 years (regardless of gender) who meet the indications for YAMANE technique.\n2. Patients who can complete a follow-up period of at least 3 months after surgery.\n3. Patients or their legal guardians who provide informed consent to participate in this study.\n\nExclusion Criteria:\n\n1. Patients with concurent secondary qlaucoma, retinal detachment, strabismus, or other relevant ocular complications (excluding refractive errors).\n2. Patients participating in other trials that may affect the results of this study.","ALL","4 Years","18 Years",{"count":68,"type":69},54,"ESTIMATED","INTERVENTIONAL",[72],"NA","This is a single-blind, single-center, parallel-group randomized controlled trial with the following objectives: First, researchers aim to compare the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion in YAMANE technique for patients with congenital ectopia lentis. Second, the goal is to investigate the mean absolute refractive prediction error, IOL tilt and decentration, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and corneal endothelial cell count at 3 months postoperatively. Third, it intends to explore the incidence of postoperative complications of the two needle insertion positions in this specific surgical method. Finally, this study aims to provide evidence for ophthalmic clinical practice, explore the optimal needle insertion point, and offer more precise and safe surgical plans for patients requiring sutureless transscleral IOL fixation.",[75],"Congenital Ectopia Lentis","NOT_YET_RECRUITING","2026-03-02",{"date":79,"type":80},"2026-03-04","ACTUAL",{"date":82,"type":69},"2026-02-28",{"date":84,"type":69},"2027-08-30",{"name":5,"class":6},1]