[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635183":3},{"organization":4,"armGroups":7,"interventions":37,"overallOfficials":70,"centralContacts":75,"locations":81,"responsibleParty":100,"collaborators":47,"id":103,"slug":104,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":47,"eligibilityCriteria":109,"healthyVolunteers":105,"sex":110,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":47,"studyType":116,"phases":117,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":84,"whyStopped":47,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":134},{"fullName":5,"class":6},"Sharda University","OTHER",[8,19,23,27,30,34],{"label":9,"type":10,"description":11,"interventionNames":12},"Saline","EXPERIMENTAL","Saline is used in the ideal conditions",[13,14,15,16,17,18],"Other: 940 nm diode laser","Other: apple cider vinegar","Other: Gymnema Sylvestre","Other: Saline (NaCl)","Other: Diode laser and Gymnema Sylvestre","Other: Diode laser and apple cider vinegar",{"label":20,"type":10,"description":21,"interventionNames":22},"940 nm diode laser","it is used for disinfecting the canal",[13,14,15,16,17,18],{"label":24,"type":10,"description":25,"interventionNames":26},"Apple cider vinegar","It is used as irrigating agent",[13,14,15,16,17,18],{"label":28,"type":10,"description":25,"interventionNames":29},"Gymnema sylvestre",[13,14,15,16,17,18],{"label":31,"type":10,"description":32,"interventionNames":33},"940 diode laser and Apple cider vinegar","For disinfecting the canal",[13,14,15,16,17,18],{"label":35,"type":10,"description":32,"interventionNames":36},"940 diode laser and Gymnema sylvestre",[13,14,15,16,17,18],[38,43,48,54,60,66],{"type":6,"name":20,"description":39,"armGroupLabels":40,"otherNames":41},"laser for irrigation",[31,35,20,24,28,9],[42],"diode laser",{"type":6,"name":44,"description":45,"armGroupLabels":46,"otherNames":47},"apple cider vinegar","5% apple cider vinegar",[31,35,20,24,28,9],null,{"type":6,"name":49,"description":50,"armGroupLabels":51,"otherNames":52},"Gymnema Sylvestre","antidiabetic agent",[31,35,20,24,28,9],[53],"gudmar",{"type":6,"name":55,"description":56,"armGroupLabels":57,"otherNames":58},"Saline (NaCl)","saline is used as ideal irrigant",[31,35,20,24,28,9],[59],"saline",{"type":6,"name":61,"description":62,"armGroupLabels":63,"otherNames":64},"Diode laser and Gymnema Sylvestre","This is the combination disinfection",[31,35,20,24,28,9],[65],"combination therapy",{"type":6,"name":67,"description":68,"armGroupLabels":69,"otherNames":47},"Diode laser and apple cider vinegar","combination therapy used will enhance the disinfection",[31,35,20,24,28,9],[71],{"name":72,"affiliation":73,"role":74},"Dr Ekta Choudhary, MDS","School of Dental Sciences , Sharda University","STUDY_DIRECTOR",[76],{"name":77,"role":78,"phone":79,"phoneExt":47,"email":80},"Lakshmi Pandey, MDS","CONTACT","+917349052235","drlakshmipandey024@gmail.com",[82],{"facility":83,"status":84,"city":85,"state":86,"zip":87,"country":88,"countryCode":89,"cosmosGeoPoint":90,"geoPoint":95,"contacts":96},"Dr Lakshmi Pandey","RECRUITING","Noida","Uttar Pradesh","201310","India","IN",{"type":91,"coordinates":92},"Point",[93,94],77.33,28.58,{"lat":94,"lon":93},[97],{"name":98,"role":78,"phone":99,"phoneExt":47,"email":80},"Lakshmi Pandey","07349052235",{"type":101,"investigatorFullName":83,"investigatorTitle":102,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"PRINCIPAL_INVESTIGATOR","Associate professor","100635183","effect-of-diode-laser-gudmar-and-vinegar-in-diabetic-patients-during-root-canal-treatment-100635183",false,"NCT07549373","Effect of Diode Laser, Gudmar and Vinegar in Diabetic Patients During Root Canal Treatment","Antibacterial Effect Of 940nm Diode Laser, Apple Cider Vinegar And Gymnema Sylvestre In Diabetic Patients With Apical Periodontitis Against Peptostreptococcus Species- A Randomized Clinical Trial","Inclusion Criteria:\n\n* Using radiographs, intraoral periapical radiographs (RVG) primary endodontic infection will be selected.\n* Multirooted teeth , root with periapical lesion will be selected\n* Type 2 diabetics between the ages of 25 years and 60 years will be chosen; both male and female patients\n* A fasting blood sugar level of 126 mg\u002Fdl and a random blood sugar level of less than 200 mg\u002Fdl\n* HbA1c (glycated haemoglobin) ≥ 6.5%\n\nExclusion Criteria:\n\n* Patients with systemic conditions other than type 2 diabetes\n* Women who are pregnant\n* Those patients that have used antibiotics within the previous three months,\n* Those patients that have teeth with developmental defects, calcified canals,\n* Teeth that cannot be isolated with rubber dams,\n* Tortuous canals\n* Roots that are fractured","ALL","25 Years","60 Years",{"count":114,"type":115},90,"ESTIMATED","INTERVENTIONAL",[118],"NA","Methodology\n\nPatient with diabetes 2 with informed consent -convenience sampling over a one year period.The tooth isolated with a rubber dam and the correct disinfection procedures will be used. researcher will do the Access preparation Working length -electronic apex locator (Dentsply Propex II) as well as a radiographic approach.\n\nAfter the canals will be obturated using ZOE sealer and gutta percha and post endodontic restoration is done using composite restoration. Patient is kept on follow up for 7days, 15 days, 30 days ,45 days and 60 days Clinical outcome is measure using periapical radiograph (RVG) Pain is measured using visual analog scale to mark the pain intensity. Data will be analysed statistically To enlarge the root canals (ISO size 20 file)\n\nA sterile paper point inside the root canal for one minute until the apex of the root canal is reached\n\nUsing T.E Buffer, samples will be delivered to the School Of Basic Life Sciences, Sharda University.\n\nThe samples will be subjected to traditional PCR analysis for the detection of Peptostreptococcus spp. in the root canal.\n\nGrouping Following instrumentation, 5% NaOCl and 17% EDTA irrigation will be done. Control group (n=15) The final irrigant will be saline Group 1 (n=15) Irrigation using 5% apple cider vinegar done The final irrigant will be saline Group 2 (n=15) Diode laser is used for disinfection in the presence of saline Group 3 (n=15) Gymnema Sylvestre Mother Tincture Q 1000 CH solution is used for disinfection in the presence of saline Group 4 (n=15) Diode laser is used for disinfection in the presence of 5% apple cider vinegar. The final irrigant will be saline Group 5 (n=15) Diode laser is used for disinfection in the presence of Gymnema Sylvestre Mother Tincture Q 1000 CH solution. The final irrigant will be saline\n\nAfter cleaning and shaping, samples will be collected and sent through T.E. Buffer to the School Of Basic Life Sciences, Sharda University.\n\nThe samples will be subjected to traditional PCR analysis for the detection of Peptostreptococcus spp. in the root canal.",[121],"Diabete Type 2",[123,124,24,28],"Endodontics","Diode laser","2026-05-24",{"date":127,"type":128},"2026-05-28","ACTUAL",{"date":130,"type":115},"2026-05-01",{"date":132,"type":115},"2027-05-01",{"name":5,"class":6},1]