[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608507":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":69,"collaborators":26,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":26,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":98,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"University Hospital, Clermont-Ferrand","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active group","ACTIVE_COMPARATOR","Patients will receive 10 sessions of active tDCS stimulation (2mA, 20 minutes, 0.1mA\u002Fs ramp-up and ramp-down), in addition to conventional rehabilitation.",[13],"Device: Active tDCS",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","SHAM_COMPARATOR","Patients will receive 10 sessions of sham tDCS stimulation (2mA, 20 minutes, 0.1mA\u002Fs ramp-up, stimulation stopped after the current ramp), in addition to conventional rehabilitation.",[19],"Device: Sham tDCS",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Active tDCS","Patients will receive 10 sessions of tDCS stimulation (2mA, 20 minutes with a current on\u002Foff ramp of 0.1 mA\u002Fs) delivered with a Sooma DUO stimulator. Sooma DUO is a transcranial direct current stimulation (tDCS) device. The device generates a current that modulates brain activity. This current is delivered via electrodes attached to the patient's head.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham tDCS","Patients will receive 10 sessions of sham tDCS stimulation (2mA, 20 minutes, 0.1mA\u002Fs ramp-up, stimulation stopped after the current ramp), delivered with a Sooma DUO stimulator. Sooma DUO is a transcranial direct current stimulation (tDCS) device. The device generates a current that modulates brain activity. This current is delivered via electrodes attached to the patient's head.",[15],[32],{"name":33,"affiliation":5,"role":34},"Xavier Moisset","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Lise Laclautre","CONTACT","334.73.754.963","promo_interne_drci@chu-clermontferrand.fr",[42,57],{"facility":43,"status":26,"city":44,"state":26,"zip":26,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"CHU Clemront-Ferrand","Clermont-Ferrand","France","FR",{"type":48,"coordinates":49},"Point",[50,51],3.08682,45.77969,{"lat":51,"lon":50},[54,56],{"name":37,"role":38,"phone":55,"phoneExt":26,"email":40},"04 73 75 11 95",{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":58,"status":26,"city":59,"state":26,"zip":60,"country":45,"countryCode":46,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"CH Etienne Clémentel","Enval","63530",{"type":48,"coordinates":62},[63,64],3.04981,45.89921,{"lat":64,"lon":63},[67],{"name":37,"role":38,"phone":68,"phoneExt":26,"email":40},"+33 4 73 75 11 95",{"type":70,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100608507","effect-of-early-neuromodulation-coupled-with-rehabilitation-on-the-prevention-of-post-stroke-pain-100608507",false,"NCT07202455","Effect of Early Neuromodulation Coupled With Rehabilitation on the Prevention of Post-stroke Pain","ENADA","Inclusion Criteria:\n\n* Age ≥18 years\n* Ischemic or hemorrhagic stroke confirmed by MRI or scanner\n* Lesion(s) in somato-sensory areas (i.e. mainly in: the pons, thalamus, internal capsule, basal ganglia and operculo-insular regions)\n* Sensory and\u002For motor deficit requiring rehabilitation\n* Subacute stage (7 to 45 days post-stroke)\n* No neurological deficit or chronic neuropathic pain prior to stroke\n* No neuropathic pain at inclusion\n* Patient can be followed throughout the study.\n* Information letter read and understood\n* Able to give informed consent to participate in research\n* Affiliation with a social security scheme\n\nExclusion Criteria:\n\n* Contraindication to tDCS (epilepsy\u002Fhistory of epilepsy, intracranial ferromagnetic material or implanted stimulator, acute eczema or irritated skin over the stimulation area)\n* Contraindication to MRI (use of a pacemaker or insulin pump, wearing of a metal prosthesis, intracerebral clip or piercing, claustrophobia)\n* Cognitive or language difficulties preventing comprehension of instructions and\u002For correct clinical assessment\n* Patients participating in another research protocol involving a drug in the 30 days prior to inclusion\n* Drug or psychoactive substance abuse\n* Pregnant or breast-feeding women\n* Patients under guardianship or curatorship, deprived of liberty, safeguard of justice\n* Major depression\n* Patients with Parkinson's disease\n* The presence of pre-existing lesions \\>1.5 cm (maximum diameter) in a cerebral area belonging to the anatomically defined sensorimotor system\n* Alcohol abuse\n* Severe psychiatric disorders (e.g., schizophrenia)\n* Any tumor disease with a life expectancy of \\\u003C1 year\n* Increased intracranial pressure\n* Patients with a medical device containing electronics or conductive materials\n* Patients on continuous oxygen (system not adapted)","ALL","18 Years",{"count":81,"type":82},60,"ESTIMATED","INTERVENTIONAL",[85],"NA","This is a prospective clinical study to evaluate the efficacy of tDCS stimulation, coupled with conventional rehabilitation, on the development of post-stroke neuropathic pain.\n\nThe study involves a double-blind, randomized, sham-controlled experimental protocol involving 2 parallel groups with patients allocated according to a Fleming design (40 patients in the active group, 20 patients in the control group).\n\nThe study is aimed at sub-acute post-stroke patients. After recruitment, they will receive 10 sessions of tDCS stimulation (2mA, 20 minutes with a current on\u002Foff ramp of 0.1 mA\u002Fs). For the control group, stimulation will stop after the current ramp.",[88,89,90],"Stroke","Neuropathic Pain","Central Post Stroke Pain",[92,93,94,95,96,97],"neuropathic pain","prevention","stroke","central post stroke pain","neuromodulation","tDCS","NOT_YET_RECRUITING","2025-12-17",{"date":101,"type":102},"2025-12-23","ACTUAL",{"date":104,"type":82},"2026-01-01",{"date":106,"type":82},"2029-04-30",{"name":5,"class":6},2]