[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629740":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":52,"collaborators":18,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":81,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Uludag University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ESP Block Group","EXPERIMENTAL","Patients undergoing elective laparoscopic cholecystectomy who will receive bilateral ultrasound-guided erector spinae plane block in addition to standard general anesthesia for postoperative analgesia.",[13],"Procedure: Erector Spinae Plane Block",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","Patients undergoing elective laparoscopic cholecystectomy who will receive standard general anesthesia and postoperative analgesic management without erector spinae plane block.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Erector Spinae Plane Block","Ultrasound-guided bilateral erector spinae plane block performed at the thoracic level following induction of general anesthesia to provide postoperative thoracoabdominal analgesia.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Selcan Akesen, Assoc. Prof. MD","CONTACT","00902242953274","selcanakesen@uludag.edu.tr",[32],{"facility":33,"status":18,"city":34,"state":34,"zip":35,"country":36,"countryCode":18,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Bursa Uludağ University Faculty of Medicine Hospital","Bursa","16059","Turkey (Türkiye)",{"type":38,"coordinates":39},"Point",[40,41],29.06013,40.19559,{"lat":41,"lon":40},[44,47,49],{"name":45,"role":28,"phone":46,"phoneExt":18,"email":30},"Selcan Akesen, Associate Professor, MD","0090224 2950000",{"name":45,"role":48,"phone":18,"phoneExt":18,"email":18},"PRINCIPAL_INVESTIGATOR",{"name":50,"role":51,"phone":18,"phoneExt":18,"email":18},"Mahsa Azizi, MD","SUB_INVESTIGATOR",{"type":48,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Selcan Akesen","Associate Professor of Anesthesiology","100629740","effect-of-erector-spinae-plane-block-on-postoperative-respiratory-function-after-laparoscopic-cholecystectomy-100629740",false,"NCT07478601","Effect of Erector Spinae Plane Block on Postoperative Respiratory Function After Laparoscopic Cholecystectomy","Effect of Ultrasound-Guided Erector Spinae Plane Block on Postoperative Pain and Respiratory Function in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Study","ESP-LC","Inclusion Criteria:\n\nAge between 18 and 65 years ASA physical status I-III-- III Patients scheduled for elective laparoscopic cholecystectomy under general anesthesia Ability to perform spirometry tests Provision of written informed consent\n\nExclusion Criteria:\n\nPatient refusal to participate Chronic pulmonary disease (e.g., COPD, asthma, restrictive lung disease) Morbid obesity (BMI ≥ 35 kg\u002Fm²) Coagulopathy or anticoagulant therapy Local infection at the block site Allergy to local anesthetic agents Pregnancy Previous thoracic surgery Neuromuscular disease affecting respiratory function Conversion from laparoscopic to open surgery Inability to perform postoperative spirometry","ALL","18 Years","70 Years",{"count":67,"type":68},70,"ESTIMATED","INTERVENTIONAL",[71],"NA","Postoperative pulmonary dysfunction is frequently observed after laparoscopic abdominal surgery due to the combined effects of general anesthesia, pneumoperitoneum, diaphragmatic dysfunction, and postoperative pain. These factors may impair respiratory mechanics, reduce lung volumes, and negatively affect postoperative recovery. Effective postoperative analgesia plays a crucial role in preserving respiratory function by allowing adequate ventilation and reducing pain-related respiratory limitation.\n\nThe erector spinae plane (ESP) block is a relatively novel ultrasound-guided fascial plane block that provides thoracoabdominal analgesia through the spread of local anesthetic along the paraspinal fascial planes. By reducing postoperative pain and opioid consumption, ESP block may contribute to improved respiratory mechanics and preservation of postoperative pulmonary function.\n\nThe aim of this prospective randomized controlled study is to evaluate the effect of ultrasound-guided erector spinae plane block on postoperative respiratory function and pain in patients undergoing elective laparoscopic cholecystectomy. Patients will be randomized into two groups: an ESP block group receiving bilateral ultrasound-guided erector spinae plane block and a control group receiving standard analgesic management.\n\nPostoperative respiratory parameters will be evaluated using spirometry measurements including forced expiratory volume in one second (FEV1), forced vital capacity (FVC), the FEV1\u002FFVC ratio, and forced expiratory flow at 25-75% of the pulmonary volume (FEF25-75). In addition, arterial blood gas parameters and postoperative pain scores will be assessed and compared between the groups.\n\nThe study aims to determine whether ultrasound-guided erector spinae plane block improves postoperative respiratory function and contributes to better postoperative recovery in patients undergoing laparoscopic cholecystectomy.",[74],"Cholelithiasis",[74,22,76,77,78,79,80],"Postoperative Respiratory Function","Laparoscopic Cholecystectomy","Postoperative Pain","Regional Anesthesia","Spirometry","NOT_YET_RECRUITING","2026-03-12",{"date":84,"type":85},"2026-03-17","ACTUAL",{"date":87,"type":68},"2026-05-24",{"date":89,"type":68},"2027-06-25",{"name":5,"class":6},1]