[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583164":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":56,"collaborators":29,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":29,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":29,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":41,"whyStopped":29,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Northern Arizona University","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","Participants exercise for 90 minutes trying to remain cool with fans and limited clothing.",[13,14],"Behavioral: Exercise","Behavioral: Heat strain",{"label":16,"type":10,"description":17,"interventionNames":18},"Heat strain","Participants exercise for 90 minutes wearing winter and rain clothes to develop heat strain.",[13,14],{"label":20,"type":21,"description":22,"interventionNames":23},"Control","PLACEBO_COMPARATOR","Resting control for 90 minutes. Not allowed to exercise.",[13,14],[25,30],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"BEHAVIORAL","Exercise for 90 minutes (cycling) while minimizing thermal strain",[20,9,16],null,{"type":26,"name":16,"description":31,"armGroupLabels":32,"otherNames":29},"Exercise for 90 minutes (cycling) while maximizing thermal strain",[20,9,16],[34],{"name":35,"role":36,"phone":37,"phoneExt":29,"email":38},"Travis Gibbons, PhD","CONTACT","928-523-4002","travis.gibbons@nau.edu",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Flagstaff","Arizona","86011","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-111.65127,35.19807,{"lat":51,"lon":50},[54],{"name":55,"role":36,"phone":37,"phoneExt":29,"email":38},"TRAVIS GIBBONS, PhD",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Travis Gibbons","Assistant Professor","100583164","effect-of-exercise-and-heat-stress-on-acute-cardiometabolic-adaptations-in-healthy-young-adults-100583164",false,"NCT06872762","Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults","Does Heat Stress Improve the Acute Metabolic and Cardiovascular Adaptations to Exercise","Inclusion Criteria:\n\n-regularly physically active as determined via ParQ+\n\nExclusion Criteria:\n\n* smokers\n* bronchial asthma\n* chronic obstructive pulmonary disease\n* obese\n* alcoholism\n* requiring daily medications that may effect responses to exercise,\n* anti-arrhythmogenics\n* inhalers\n* history of cardiovascular, respiratory, neurological, skeletal muscle disease\n* irregular\u002Fabsent menstrual cycle (females)\n* unexpected responses to pre-experimental exercise tests\n* previous diagnosis of heat stroke",true,"ALL","18 Years","50 Years",{"count":72,"type":73},15,"ESTIMATED","INTERVENTIONAL",[76],"NA","Life in space is completely void of physical and environmental stress. It is well known that living things need regular physical stress (e.g. exercise) to remain strong, functional and healthy. More and more research is showing that regular environmental stress, for example heat and hypoxia, can further improve physical health. Astronauts aboard the international space station (ISS) exercise for 1-2 hours every day to avoid physical deconditioning that would otherwise cause them to age rapidly in space. Although physical exercise is very effective in remedying this deconditioning, today's astronauts still have physiological changes that indicate accelerated aging. This is a cause for concern given NASA's priority to travel to mars within the next decade; a mission that will require at least double the duration in space for our astronauts. The investigators think that the complete absence of environmental stress, i.e., heat, may be contributing to the accelerated aging that occurs during spaceflight. Our study will assess the health effects of adding heat stress to exercise that could be performed in space by astronauts. The goal is to inform best practice for astronauts to avoid physical deconditioning during long-duration spaceflight. This information will also be relevant to life on earth as spaceflight is a model of inactivity here on earth. Therefore, the potential benefits of adding heat stress will likely translate to life in space and on earth.",[9,79,80],"Heat Strain","Control Condition",[82,83,84,85],"exercise","heat strain","glucose tolerance test","arterial compliance","2025-03-06",{"date":88,"type":89},"2025-03-12","ACTUAL",{"date":91,"type":89},"2025-03-01",{"date":93,"type":73},"2026-05-21",{"name":5,"class":6},1]