[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553823":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":49,"centralContacts":54,"locations":59,"responsibleParty":83,"collaborators":86,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":40,"eligibilityCriteria":95,"healthyVolunteers":96,"sex":97,"minAge":98,"maxAge":40,"enrollmentInfo":99,"targetDuration":40,"studyType":102,"phases":103,"briefSummary":105,"conditions":106,"keywords":108,"overallStatus":111,"whyStopped":40,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"St. Boniface Hospital","OTHER",[8,13,19,24,29],{"label":9,"type":6,"description":10,"interventionNames":11},"No Flax Product","175 g yogurt containing no flax product",[12],"Dietary Supplement: 0 g Flax",{"label":14,"type":15,"description":16,"interventionNames":17},"40 g whole ground flaxseed","EXPERIMENTAL","175 g yogurt with 40 g whole ground flaxseed",[18],"Dietary Supplement: 40 g whole ground flaxseed",{"label":20,"type":15,"description":21,"interventionNames":22},"40 g roasted then ground whole flaxseed","175 g yogurt with 40 g roasted then ground whole flaxseed",[23],"Dietary Supplement: 40 g roasted then ground whole flaxseed",{"label":25,"type":15,"description":26,"interventionNames":27},"40 g of whole intact flaxseeds","175 g yogurt with 40 g of whole intact flaxseeds",[28],"Dietary Supplement: 40 g of whole intact flaxseeds",{"label":30,"type":15,"description":31,"interventionNames":32},"28 g flax hulls","175 g yogurt with 28 g flax hulls",[33],"Dietary Supplement: 28 g flax hulls",[35,41,43,45,47],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"DIETARY_SUPPLEMENT","0 g Flax","175 g yogurt with no flax product",[9],null,{"type":36,"name":14,"description":16,"armGroupLabels":42,"otherNames":40},[14],{"type":36,"name":20,"description":21,"armGroupLabels":44,"otherNames":40},[20],{"type":36,"name":25,"description":26,"armGroupLabels":46,"otherNames":40},[25],{"type":36,"name":30,"description":31,"armGroupLabels":48,"otherNames":40},[30],[50],{"name":51,"affiliation":52,"role":53},"Heather Blewett, PhD","Agriculture and Agri-Food Canada","PRINCIPAL_INVESTIGATOR",[55],{"name":51,"role":56,"phone":57,"phoneExt":40,"email":58},"CONTACT","204-237-2954","hblewett@sbrc.ca",[60],{"facility":61,"status":40,"city":62,"state":63,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"I. H. Asper Clinical Research Institute","Winnipeg","Manitoba","R2H 2A6","Canada","CA",{"type":68,"coordinates":69},"Point",[70,71],-97.14704,49.8844,{"lat":71,"lon":70},[74,76,77,79,81],{"name":75,"role":56,"phone":57,"phoneExt":40,"email":58},"Heather J Blewett, PhD",{"name":75,"role":56,"phone":40,"phoneExt":40,"email":40},{"name":78,"role":56,"phone":40,"phoneExt":40,"email":40},"Véronique J Barthet, PhD",{"name":80,"role":56,"phone":40,"phoneExt":40,"email":40},"Michel Aliani, PhD",{"name":82,"role":56,"phone":40,"phoneExt":40,"email":40},"Lovemore Malunga, PhD",{"type":53,"investigatorFullName":84,"investigatorTitle":85,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"Dr. Heather Blewett","Principle Investigator",[87],{"name":52,"class":88},"OTHER_GOV","100553823","effect-of-flax-in-yogurt-on-blood-cyanide-levels-100553823",false,"NCT06491095","Effect of Flax in Yogurt on Blood Cyanide Levels","A Randomized, Controlled, Cross-over Trial Examining the Effect of Flaxseed on Blood Cyanide Levels in Healthy Adults","Inclusion Criteria:\n\n1. Generally healthy adult, 18 years or older;\n2. Willing to provide informed consent;\n3. Willing\u002Fable to comply with the requirements of the study.\n\nExclusion Criteria:\n\n1. Pregnant or lactating;\n2. Medical history of disease that is currently under treatment;\n3. Active treatment for any type of cancer within 1 year prior to study start;\n4. Presence of a gastrointestinal disorder, daily use of any stomach acid-lowering medications or laxatives (including fibre supplements) within the past month or antibiotic use within the past 6 weeks;\n5. Plasma concentration of vitamin B12 \\\u003C 148 pmol\u002FL;\n6. Complete blood count outside normal range;\n7. Medical history of liver disease or liver dysfunction (defined as plasma AST or ALT ≥3 times the upper limit of normal (ULN));\n8. Fasting blood glucose ≥6.1 mmol\u002FL and\u002For HbA1c ≥6.0%;\n9. Fasting plasma total cholesterol \\>7.8 mmol\u002FL;\n10. Fasting plasma HDL \\\u003C0.9 mmol\u002FL;\n11. Fasting plasma LDL \\>5.0 mmol\u002FL;\n12. Fasting plasma triglycerides \\>2.3 mmol\u002FL;\n13. Systolic blood pressure \\>140 mmHg or diastolic blood pressure \\>90 mmHg;\n14. Major surgery within the last 3 months;\n15. Smoking, use of tobacco, vape or cannabis (within the last week);\n16. Allergies to flaxseed or yogurt;\n17. Aversion or unwillingness to eat study foods;\n18. Participation in another clinical trial, current or in the past 4 weeks",true,"ALL","18 Years",{"count":100,"type":101},12,"ESTIMATED","INTERVENTIONAL",[104],"NA","A randomized, controlled, cross-over post-prandial trial in healthy human volunteers will be conducted at the IH Asper Institute to determine the effect whole ground flaxseed, roasted then ground whole flaxseed, whole intact flaxseed and flaxseed hulls mixed into yogurt on blood cyanide levels.",[107],"Healthy",[109,110],"Flax","Blood Cyanide","NOT_YET_RECRUITING","2024-11-26",{"date":114,"type":115},"2024-12-02","ACTUAL",{"date":117,"type":101},"2025-01-16",{"date":119,"type":101},"2026-03-28",{"name":5,"class":6},1]