[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575971":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":55,"locations":65,"responsibleParty":81,"collaborators":30,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":30,"eligibilityCriteria":88,"healthyVolunteers":85,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":30,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":101,"overallStatus":105,"whyStopped":30,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Peking University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"resveratrol intervention","EXPERIMENTAL","participants receive different levels of resveratrol",[13,14,15],"Dietary Supplement: resveratrol_L","Dietary Supplement: resveratrol_H","Other: placebo_resveratrol",{"label":17,"type":10,"description":18,"interventionNames":19},"prebiotic intervention","subjects receive different levels of prebiotics",[20,21,22,23],"Dietary Supplement: Prebiotic_L","Dietary Supplement: Prebiotic_M","Dietary Supplement: Prebiotic_H","Other: placebo_Bif",[25,31,35,39,43,47,51],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DIETARY_SUPPLEMENT","Prebiotic_L","subject will receive a low-dosage (1\\*10\\^5) of Bifidobacterium. animalis subsp.Lactis A6 Strain",[17],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"resveratrol_L","subject will receive a low-dosage (300mg\u002Fd) of resveratrol",[9],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Prebiotic_M","subject will receive a medium-dosage (1\\*10\\^8) of Bifidobacterium. animalis subsp.Lactis A6 Strain",[17],{"type":26,"name":40,"description":41,"armGroupLabels":42,"otherNames":30},"Prebiotic_H","subjects will receive a high-dosage (1\\*10\\^10) of Bifidobacterium. animalis subsp.Lactis A6 Strain",[17],{"type":26,"name":44,"description":45,"armGroupLabels":46,"otherNames":30},"resveratrol_H","subject will receive a low-dosage (600mg\u002Fd) of resveratrol",[9],{"type":6,"name":48,"description":49,"armGroupLabels":50,"otherNames":30},"placebo_Bif","subjects will receive placebo (one look-alike sunbstance that contains no prebiotics)",[17],{"type":6,"name":52,"description":53,"armGroupLabels":54,"otherNames":30},"placebo_resveratrol","subjects will receive placebo (one look-alike sunbstance that contains no resveratrol)",[9],[56,61],{"name":57,"role":58,"phone":59,"phoneExt":30,"email":60},"Fan Zhang, postgraduate","CONTACT","(86) 13260267609","zhiyouzhangfan@126.com",{"name":62,"role":58,"phone":63,"phoneExt":30,"email":64},"Yalin Zhou, postdoctor","13260267609","zylyingyang@163.com",[66],{"facility":5,"status":30,"city":67,"state":68,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":77,"contacts":78},"Beijing","Beijing Municipality","100083","China","CN",{"type":73,"coordinates":74},"Point",[75,76],116.39723,39.9075,{"lat":76,"lon":75},[79],{"name":5,"role":58,"phone":80,"phoneExt":30,"email":64},"086+01082802552",{"type":82,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100575971","effect-of-food-derived-active-components-on-digestive-tract-health-in-adults-with-irritable-bowel-syndrome-100575971",false,"NCT06779214","Effect of Food-derived Active Components on Digestive Tract Health in Adults with Irritable Bowel Syndrome","Inclusion Criteria:\n\n* met the Western Medicine Rome IV diagnostic criteria for diarrheal IBS\n* 18 and 60 years old\n* subjects voluntarily sign informed consent forms.\n\nExclusion Criteria:\n\n* Having a disease that may affect the gut microbiome (e.g., inflammatory bowel disease, celiac disease, diabetes)\n* Abdominal pain or diarrhea due to organic disease\n* Patients with abdominal surgery\n* Patients with serious mental illness and complications of heart, brain, liver, kidney and other systems\n* Unable to communicate normally or skilled in the use of communication equipment\n* Having serious mental problems or taking related drugs\n* Drug or alcohol abusers\n* People with special diets (such as vegetarians) or eating disorders or are receiving therapeutic dietary interventions\n* Had used antibiotics, probiotics, other drugs that may affect the study\n* Participants who are participating in other clinical trials\n* Pregnant or lactating women","ALL","18 Years","60 Years",{"count":93,"type":94},180,"ESTIMATED","INTERVENTIONAL",[97],"NA","The goal of this clinical trial is to learn if Bifidobacterium. animalis subsp.\n\nLactis A6 Strain or resveratrol to improve the symptoms of diarrhea-predominate irritable bowel syndromes (IBS-D). The main questions it aims to answer are:\n\n1. Does Bifidobacterium animalis subsp.Lactis A6 Strain or resveratrol improve the symptoms of IBS-D.\n2. What is the optimal intervention dose of Bifidobacterium. animalis subsp.Lactis A6 Strain or resveratrol to improve IBS-D\n\nResearchers will compare Bifidobacterium. animalis subsp.Lactis A6 Strain or resveratrol interventions to placebo (one look-alike sunbstance that contains no interventions substance) to see if Bifidobacterium. animalis subsp.Lactis A6 Strain or resveratrol relief the symptoms of patients with IBS-D.\n\nParticipants will:\n\n1. Take Bifidobacterium. animalis subsp.Lactis A6 Strain or resveratrol every day for 30 days.\n2. Visit the clinic once every 15 days for checkups and tests.",[100],"Irritable Bowel Syndrome - Diarrhoea",[102,103,104],"Diarrhea-predominate Irritable bowel syndrome","probiotics","polyphenols","NOT_YET_RECRUITING","2025-01-12",{"date":108,"type":109},"2025-01-16","ACTUAL",{"date":111,"type":94},"2025-02-28",{"date":113,"type":94},"2025-12-31",{"name":5,"class":6},1]