[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567790":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":33,"centralContacts":41,"locations":48,"responsibleParty":63,"collaborators":23,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":23,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":23,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":93,"whyStopped":23,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Selcuk University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Functional Inspiratory Muscle Training Group","EXPERIMENTAL","The functional inspiratory muscle training (FIMT) group (n=21) will receive basic inspiratory muscle training (IMT) with a device capable of delivering threshold pressure loading (POWERbreathe) for the first four weeks. The first, middle and last sessions of the week will be supervised (face-to-face) and other sessions will be unsupervised (at home, twice a day, totaling 30 minutes). The intensity of inspiratory muscle training will be adjusted to 50-60% of maximal inspiratory pressure and these measurements will be repeated at the beginning of each week and weekly pressure increases will be adjusted. After the first four weeks are completed, then inspiratory muscle training will be combined with exercises at the beginning of the fifth week, and participants will perform supervised in-person FIMT three days per week for four weeks and unsupervised home IMT on the remaining days.",[13],"Other: Functional Inspiratory Muscle Training",{"label":15,"type":10,"description":16,"interventionNames":17},"Basic Inspiratory Muscle Training Group","Basic inspiratory muscle training (IMT) group (n=21) will be given IMT with a device capable of performing threshold pressure loading (POWERbreathe Classic Light Resistance, PowerBreath, IMT Technologies Ltd, Birmingham, UK) for eight weeks. The first day of the week, the middle of the week and the last session will be supervised (face-to-face), and the other sessions will be unsupervised (at home, twice a day, 30 minutes in total). The intensity of inspiratory muscle training will be adjusted to be 50-60% of the maximal inspiratory pressure, and these measurements will be repeated at the beginning of each week and weekly pressure increases will be adjusted.",[18],"Other: Basic Inspiratory Muscle Training",{"label":20,"type":21,"description":22,"interventionNames":23},"Control Group","NO_INTERVENTION","Participants in the control group (n=21) will be informed about the benefits of at least 150-300 minutes of moderate intensity or 75-150 minutes of vigorous intensity aerobic physical activity and breathing exercises per week and exercise recommendations will be given. Both daily physical activities and breathing exercises will be monitored with a pre-prepared exercise tracking form. Participants will be called to the laboratory for clinical measurements at the beginning and end of the study.\n\nParticipants in the control group will be taught to do diaphragmatic breathing, thoracic expansion, pursed lip breathing and breath control breathing exercises for 20 minutes a day and will be given as home exercises without supervision, with 1-2 minutes of rest between each exercise.",null,[25,29],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":23},"Functional Inspiratory Muscle Training","The functional inspiratory muscle training group will perform basic inspiratory muscle training in the first four weeks of the study and the following exercises with the Powerbreath device in muscle training in the following four weeks:\n\n1. Diaphragmatic breathing exercises\n2. Warm-up exercises\n3. Trunk strength and lumbopelvic stability exercises\n4. Dynamic trunk exercises\n5. Postural control exercises\n6. Cool-down exercises",[9],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":23},"Basic Inspiratory Muscle Training","The basic inspiratory muscle training group will do muscle training with the POWERbreathe device for eight weeks.",[15],[34,38],{"name":35,"affiliation":36,"role":37},"İsmail ÖZSOY, Assoc. Prof. Dr.","Selcuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Konya, Türkiye","STUDY_DIRECTOR",{"name":39,"affiliation":40,"role":37},"Selen GUR OZMEN, Assoc. Prof. Dr.","Bahcesehir University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Istanbul, Türkiye",[42],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},"Mehmet K ALTUNOK, PHD(c) in PT","CONTACT","5558175133","+90","mehmetkaan.altunok@selcuk.edu.tr",[49],{"facility":50,"status":23,"city":51,"state":52,"zip":53,"country":54,"countryCode":23,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Selcuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation","Konya","Selcuklu","42130","Turkey (Türkiye)",{"type":56,"coordinates":57},"Point",[58,59],32.48464,37.87135,{"lat":59,"lon":58},[62],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Mehmet Kaan ALTUNOK","Lecturer","100567790","effect-of-functional-inspiratory-muscle-training-in-patients-with-multiple-sclerosis-100567790",false,"NCT06672770","Effect of Functional Inspiratory Muscle Training in Patients with Multiple Sclerosis","Investigation of the Effects of Functional Inspiratory Muscle Training on Respiratory Muscle Strength, Functional Exercise Capacity and Cognitive Function in Patients with Multiple Sclerosis","Inclusion Criteria:\n\n* Diagnosed with Relapsing Remitting Type Multiple Sclerosis (RRMS),\n* EDSS (Expanded Disability Status Scale in MS: EDSS) score ranging from 1-5,\n* Able to communicate (speak, understand, read and understand Turkish),\n* Individuals who have not had an attack in the last three months,\n* Individuals who have not received respiratory-based rehabilitation in the last six months will be included in the study.\n\nExclusion Criteria:\n\n* Those with neurological diseases other than MS,\n* Those who have functional exercise restrictions,\n* Those with chronic cardiac or pulmonary diseases such as chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease and heart failure that may affect respiratory muscle strength and respiratory functions,\n* Individuals who have had pneumonia due to viral or bacterial infection in the last six months or COVID-19 positive individuals proven by PCR-RT,\n* Those with orthopedic problems, persistent neck and back pain and\u002For radiculopathy that prevent them from participating in the study,\n* Those with diagnosed psychiatric disorders,\n* Those who use tobacco and tobacco products,\n* Participants with cooperation problems that may prevent evaluations and treatment will not be included in the study.","ALL","18 Years","65 Years",{"count":78,"type":79},63,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study aims to investigate the effects of functional inspiratory muscle training, basic inspiratory muscle training and physical activity in addition to respiratory exercises on respiratory muscle strength, respiratory function, cognition, walking, balance, functional exercise capacity, physical activity, quality of life and core muscles in volunteer Multiple Sclerosis (MS) patients. This study is planned as a prospective, randomized and experimental study.",[85,26,86,87],"Core Muscles","Multiple Sclerosis","Respiratory Muscles",[89,90,91,92],"Core muscles","Functional inspiratory muscle training","Multiple sclerosis","Respiratory muscles","NOT_YET_RECRUITING","2024-11-01",{"date":96,"type":97},"2024-11-04","ACTUAL",{"date":94,"type":79},{"date":100,"type":79},"2025-12-20",{"name":5,"class":6},1]