[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100535097":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":70,"collaborators":73,"id":102,"slug":103,"hasResults":104,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":104,"sex":110,"minAge":111,"maxAge":26,"enrollmentInfo":112,"targetDuration":26,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"Skane University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High-flow oxygen therapy","EXPERIMENTAL","Intervention arm",[13],"Device: Added high-flow oxygen therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Low-flow oxygen therapy","ACTIVE_COMPARATOR","Comparison arm",[19],"Other: Standard care",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Added high-flow oxygen therapy","Added high-flow oxygen therapy using the device Lumis HFT during nighttime and at the patient's discretion daytime, with the usual care (low-flow oxygen therapy) the rest of the time.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard care","Standard care with low-flow oxygen therapy in accordance with clinical routine.",[15],[32],{"name":33,"affiliation":5,"role":34},"Magnus Ekström, MD, PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","0455731000","+46","magnus.ekstrom@med.lu.se",[42,58],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Research Unit, Blekinge University of Technology","RECRUITING","Karlskrona","Blekinge County","37185","Sweden","SE",{"type":51,"coordinates":52},"Point",[53,54],15.58661,56.16156,{"lat":54,"lon":53},[57],{"name":33,"role":37,"phone":26,"phoneExt":26,"email":40},{"facility":59,"status":44,"city":60,"state":26,"zip":61,"country":48,"countryCode":49,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Department of Heart, Lung and Clinical Physiology, Örebro University Hospital","Örebro","70185",{"type":51,"coordinates":63},[64,65],15.2066,59.27412,{"lat":65,"lon":64},[68],{"name":69,"role":37,"phone":26,"phoneExt":26,"email":26},"Josefin Sundh, MD, PhD",{"type":34,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Magnus Ekström","Associate Professor, Senior Lecturer",[74,76,79,81,83,85,87,89,91,93,95,98,100],{"name":75,"class":6},"Uppsala University Hospital",{"name":77,"class":78},"Region Stockholm","OTHER_GOV",{"name":80,"class":6},"Region Örebro County",{"name":82,"class":6},"Blekinge County Council Hospital",{"name":84,"class":6},"Blekinge Institute of Technology",{"name":86,"class":6},"Lund University",{"name":88,"class":6},"Region Östergötland",{"name":90,"class":78},"Vastra Gotaland Region",{"name":92,"class":78},"Region Västerbotten",{"name":94,"class":6},"Landstinget i Värmland",{"name":96,"class":97},"ResMed","INDUSTRY",{"name":99,"class":6},"Swedish Heart Lung Foundation",{"name":101,"class":78},"The Swedish Research Council","100535097","effect-of-high-flow-therapy-in-long-term-oxygen-therapy-100535097",false,"NCT06247397","Effect of HIgh-flow Therapy in Long-term Oxygen Therapy","Effect of HIgh-flow Therapy in Long-term Oxygen Therapy (HILOT): A Multicenter, Registry-based, Randomized Clinical Trial","HILOT","Inclusion Criteria:\n\n* Age 40 years or older\n* Ongoing LTOT: prescribed for at least 15 hours per day; and since at least 28 days as registered in Swedevox\n* COPD or ILD as main underlying reason for LTOT\n* Oxygen concentrator as stationary oxygen source in the home including night-time\n* Body mass index (BMI) \\\u003C 35 kg\u002Fm2\n\nExclusion Criteria:\n\n* Current or previous treatment with home HFOT\n* Current treatment with home mechanical ventilation\n* Current treatment with home CPAP\n* Hospitalized during the last 2 weeks\n* Current smoking or contact with flames\n* Self-reported average use of the LTOT \\\u003C 15h per day (24 hours)\n* PaCO2 (breathing air at rest) \\> 8 kPa\n* Strong clinical suspicion of obstructive sleep apnea (OSA) or obesity-related hypoventilation syndrome (OHS) (as judged by the responsible staff)\n* Inability to participate in the study procedures (as judged by the staff)\n* Not eligible for continuing LTOT due to other reason (as judged by the staff)\n* Expected survival less than 3 months (as judged by the staff)","ALL","18 Years",{"count":113,"type":114},310,"ESTIMATED","INTERVENTIONAL",[117],"NA","This is a registry-based, randomized, controlled clinical trial of the effect of added high-flow oxygen therapy (using the device Lumis HFT) during one year in people with long-term oxygen therapy (LTOT) for chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD).",[120,121,122],"Chronic Obstructive Pulmonary Disease Severe","Interstitial Lung Disease","Chronic Respiratory Failure With Hypoxia","2025-05-15",{"date":125,"type":126},"2025-05-21","ACTUAL",{"date":128,"type":126},"2024-06-10",{"date":130,"type":114},"2028-12",{"name":5,"class":6},2]