[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640111":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":45,"centralContacts":46,"locations":52,"responsibleParty":70,"collaborators":45,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":45,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":99,"overallStatus":54,"whyStopped":45,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Macao Polytechnic University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Natural Recovery Group","ACTIVE_COMPARATOR","Participants in Group A will undergo standardized rowing training at approximately 1600 meters altitude for 4 weeks. After each training session, participants will receive standard training recovery procedures without any water immersion intervention. Recovery includes passive rest, self-directed light stretching, and ad libitum hydration in a thermoneutral environment (room temperature 24°C) for 20 minutes. No thermal or hydrotherapy intervention will be provided.",[13],"Behavioral: Natural recovery",{"label":15,"type":10,"description":16,"interventionNames":17},"Hot water immersion group","Subjects in Group B will undergo the same standardized rowing training at an altitude of approximately 1600 meters for 4 weeks. After each training session, subjects will receive whole-body immersion (below the neck, with the head above water) in daily tap water at 38°C ± 0.5°C for 20 minutes. The water temperature is monitored by a precision thermometer with an error of ≤ ±0.5°C. The immersion is conducted in a standardized indoor facility, and the time is 16:00 on Tuesday, Thursday, and Saturday.",[18],"Behavioral: Hot water immersion",{"label":20,"type":21,"description":22,"interventionNames":23},"Hot Spring Immersion Group","EXPERIMENTAL","Participants in Group C will undergo the same standardized rowing training at approximately 1600 meters altitude for 4 weeks. After each training session, participants will receive full-body immersion (below neck, head above water) in natural hot spring water at 38°C ± 0.5°C for 20 minutes. The spring water has a pH of approximately 7.4, Na+ content of 1210 mg\u002FL, and HCO3- content of approximately 3300 mg\u002FL. Immersion will be performed in a standardized indoor facility on Tuesday, Thursday, and Saturday at 16:00, using the same protocol as Group B to maintain blinding.",[24],"Behavioral: Hot spring balneotherapy",[26,33,39],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"BEHAVIORAL","Natural recovery","Standard post-exercise recovery without water immersion. Participants rest passively in a thermoneutral environment (24°C, 50-60% humidity) for 20 minutes with ad libitum water and optional self-directed stretching. No heat, cold, or hydrotherapy interventions are applied.",[9],[32],"NR",{"type":27,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"Hot water immersion","After exercise, full-body immersion in daily tap water. Temperature: 38°C ± 0.5°C. Duration: 20 minutes per session, 3 times per week (Tuesday, Thursday, Saturday at 16:00), for 4 consecutive weeks (total of 12 sessions). Protocol: Full-body immersion below the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.",[15],[38],"HWI",{"type":27,"name":40,"description":41,"armGroupLabels":42,"otherNames":43},"Hot spring balneotherapy","After exercise, full-body immersion in natural hot spring water (pH approx. 7.4, Na+ 1210 mg\u002FL, HCO3- approx. 3300 mg\u002FL, total dissolved solids \\>1000 mg\u002FL). Temperature: 38°C ± 0.5°C. Duration: 20 minutes per session, 3 times per week (Tuesday, Thursday, Saturday at 16:00), for 4 consecutive weeks (12 sessions total). Protocol: Full-body immersion below the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.",[20],[44],"HSB",null,[47],{"name":48,"role":49,"phone":50,"phoneExt":45,"email":51},"Ziyue Ou, PHD","CONTACT","+8615626121623","p2521734@mpu.edu.mo",[53],{"facility":5,"status":54,"city":55,"state":55,"zip":45,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Macao","China","CN",{"type":59,"coordinates":60},"Point",[61,62],119.73136,31.44752,{"lat":62,"lon":61},[65,66],{"name":48,"role":49,"phone":50,"phoneExt":45,"email":51},{"name":67,"role":49,"phone":68,"phoneExt":45,"email":69},"Ziyue Ou","15626121623","105852022100090@stu.gzsport.edu.cn",{"type":71,"investigatorFullName":67,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":45,"oldOrganization":45},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100640111","effect-of-hot-spring-therapy-on-central-fatigue-elimination-during-altitude-training-100640111",false,"NCT07615478","Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training","A Randomized Controlled Trial Investigating the Effects of Hot Spring Therapy Balneotherapy on Central Activation, Cognitive Function, and Exercise Performance in Adolescent Rowers During Altitude Training","HSCF-AHT","Inclusion Criteria:\n\n* Male or female aged 12-16 years- Healthy with no serious chronic diseases or skin conditions\n* At least 1 year of systematic rowing training experience\n* Currently undergoing centralized altitude training at approximately 1600 meters- No history of systematic hot spring or spa immersion within the past month\n* No allergy history to sodium bicarbonate or hot spring minerals- Ability to provide written informed assent (participant) and written informed consent (parent\u002Fguardian)- No acute infection, fracture, or surgery within the past month\n* Not currently taking non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, or medications affecting autonomic or cognitive function\n\nExclusion Criteria:\n\n* History of cardiovascular, respiratory, renal, endocrine, or neurological disorders- Uncontrolled hypertension or hypotension\n* History of syncope, heat intolerance, or severe dizziness during hot water immersion- Open wounds, severe eczema, or other skin conditions contraindicating water immersion\n* Current use of beta-blockers, anticholinergics, stimulants, sedatives, or other medications affecting central nervous system function\n* Color blindness or uncorrected visual impairment affecting Stroop test performance- Pregnancy (for female participants)- Alcohol consumption or smoking\n* Shift work or trans-meridian travel within 2 weeks prior to baseline assessment\n* Any condition deemed by the investigator as unsafe for participation",true,"ALL","12 Years","16 Years",{"count":86,"type":87},27,"ESTIMATED","INTERVENTIONAL",[90],"NA","This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan). Thirty adolescent athletes (aged 12-16 years) will be stratified by sex and randomly allocated to three groups: Group A (natural recovery, no immersion), Group B (38°C pure water immersion), and Group C (38°C sodium bicarbonate hot spring immersion). Interventions will be administered 3 times per week for 4 weeks. The primary outcomes are central fatigue indices including voluntary activation (VA) and central activation ratio (CAR). Secondary outcomes encompass cognitive function (Stroop test, Psychomotor Vigilance Test), cerebral hemodynamics (functional near-infrared spectroscopy, transcranial Doppler ultrasound), exercise performance (maximal oxygen uptake, 1000m test, 500m test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets).",[93,94,95,96,97,98],"Central Fatigue","Altitude Training","Cognitive Impairment","Hydrotherapy","Balneotherapy","Sports Performance",[100,101,96,102,103],"Altitude Sickness","Cognition","Hot Springs","Athletic Performance","2026-05-22",{"date":106,"type":107},"2026-05-29","ACTUAL",{"date":109,"type":87},"2026-05-25",{"date":111,"type":87},"2026-06-25",{"name":5,"class":6},1]