[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637581":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":41,"centralContacts":42,"locations":48,"responsibleParty":62,"collaborators":41,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":41,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":41,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":92,"overallStatus":50,"whyStopped":41,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Macao Polytechnic University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Natural Recovery Group","ACTIVE_COMPARATOR","Control group participants will undergo the same altitude training protocol (altitude 1600 meters) for 4 weeks. After each training session, participants will receive standard recovery procedures, including 20 minutes of passive rest in a thermoneutral environment (room temperature 24°C), supplemented with mild hydration and self-selected stretching. No hydrothermal intervention will be provided.",[13],"Behavioral: Control Group：Natural Recovery",{"label":15,"type":10,"description":16,"interventionNames":17},"Hot water immersion group","The hot water immersion group will undergo a 4-week altitude training at 1600 meters above sea level. Subjects will receive a 20-minute hot water immersion (daily tap water, 38°C±1°C) in a standardized indoor hot spring facility. The immersion protocol includes whole-body immersion up to the neck for 20 minutes, followed by a 10-minute rest before leaving the facility. Three times per week.",[18],"Behavioral: Hot water immersion group",{"label":20,"type":21,"description":22,"interventionNames":23},"Hot Spring Immersion Group","EXPERIMENTAL","The hot spring immersion group will undergo a 4-week high-altitude training at an altitude of 1600 meters. Subjects will receive a 20-minute hot spring therapy (natural hot spring water, 38°C ± 1°C) in a standardized indoor hot spring facility. The immersion protocol includes whole-body immersion to the neck for 20 minutes, followed by a 10-minute rest before leaving the facility. Three times per week.",[24],"Behavioral: hot spring immersion group",[26,32,36],{"type":27,"name":28,"description":11,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Control Group：Natural Recovery",[9],[31],"NR",{"type":27,"name":15,"description":16,"armGroupLabels":33,"otherNames":34},[15],[35],"HWI",{"type":27,"name":37,"description":22,"armGroupLabels":38,"otherNames":39},"hot spring immersion group",[20],[40],"HSI",null,[43],{"name":44,"role":45,"phone":46,"phoneExt":41,"email":47},"Ziyue Ou, PHD","CONTACT","15626121623","395356506@qq.com",[49],{"facility":5,"status":50,"city":51,"state":41,"zip":41,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Macao","China","CN",{"type":55,"coordinates":56},"Point",[57,58],119.73136,31.44752,{"lat":58,"lon":57},[61],{"name":44,"role":45,"phone":46,"phoneExt":41,"email":47},{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":41,"oldOrganization":41},"PRINCIPAL_INVESTIGATOR","Ziyue Ou","Principal Investigator","100637581","effect-of-hot-spring-therapy-on-cognitive-function-recovery-during-altitude-training-100637581",false,"NCT07608913","Effect of Hot Spring Therapy on Cognitive Function Recovery During Altitude Training","A Randomized Controlled Trial Investigating the Effects of Balneotherapy on Cognitive Performance, Cerebral Hemodynamics, and Exercise Capacity in Healthy Adults Undergoing Simulated Altitude Training","Inclusion Criteria:\n\n* Male or female aged 11-17 years- Regular endurance training (≥3 sessions\u002Fweek) for ≥2 years\n* No history of altitude exposure \\>2000m in the past 3 months\n* No contraindications to hot water immersion (e.g., uncontrolled hypertension, severe cardiovascular disease, open wounds, pregnancy)\n* Ability to provide written informed consent\n* Willingness to abstain from other recovery modalities (e.g., massage, cryotherapy, compression garments) during the study period\n* No color blindness or uncorrected visual impairment that would affect Stroop test performance\n\nExclusion Criteria:\n\n* History of cardiovascular, respiratory, renal, or endocrine disorders\n* Current use of medications affecting autonomic function or cognition (e.g., beta-blockers, anticholinergics, stimulants, sedatives)\n* History of syncope, heat intolerance, or neurological disorders\n* Acute musculoskeletal injury within the past 6 months- Regular use of sauna, hot tub, or spa within the past month- Pregnancy or breastfeeding (for female participants)\n* Shift work or trans-meridian travel within 2 weeks prior to baseline assessment- Alcohol consumption \\>14 units\u002Fweek or smoking\n* History of traumatic brain injury, stroke, or psychiatric disorders",true,"ALL","11 Years","17 Years",{"count":78,"type":79},27,"ESTIMATED","INTERVENTIONAL",[82],"NA","This randomized controlled trial aims to investigate the effects of hot spring bath therapy on cognitive function recovery, cerebral hemodynamics, and athletic performance in athletes undergoing altitude training. Participants will be randomly assigned to either a hot spring intervention group, a hot water control group, or a blank control group. The hot spring intervention group receives hot spring baths (38°C, 20 minutes) combined with altitude training; the hot water control group receives hot water baths (38°C, 20 minutes) combined with altitude training; and the blank control group receives standard recovery procedures combined with altitude training. Primary outcome measures include cognitive performance assessments (Stroop test, psychomotor vigilance test) and cerebral hemodynamic indicators (functional near-infrared spectroscopy, transcranial Doppler ultrasound). Secondary outcomes included exercise capacity (maximal oxygen uptake, triathlon performance, 500-meter test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets). These findings may provide evidence for non-pharmacological interventions to enhance cognitive recovery and brain adaptation during altitude training.",[85,86,87,88,89,90,91],"Altitude Training Adaptation","Cognitive Function","Cerebral Hemodynamics","Exercise Performance","Hydrotherapy","Balneotherapy","Hypoxia",[93,94,95,96,89,97],"Altitude Sickness","Cognition","Cerebrovascular Circulation","Physical Performance","Hot Springs","2026-05-19",{"date":100,"type":101},"2026-05-27","ACTUAL",{"date":103,"type":79},"2026-05-25",{"date":105,"type":79},"2026-06-25",{"name":5,"class":6},1]