[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635918":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":47,"collaborators":26,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":26,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Assaf-Harofeh Medical Center","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hyperoxygenation active treatment","ACTIVE_COMPARATOR","The HYPEROXYGENATED ENVIRONMENT protocol will include a single exposure to hyperoxic environment. The session will last 60 minutes, of 100% oxygen inhalation by mask at 2 ATA. 15 minutes after reaching 2 ATA and breathing 100% oxygen - IMTP test - For measurement of peak-force at baseline and under the different oxygenation conditions, each participant will be given three attempts at every IMTP test.\n\nA three-minute rest will be given between attempts, with the aim of attaining optimal recovery",[13],"Device: Hyperbaric Oxygen Therapy - HBOT",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham","SHAM_COMPARATOR","The Sham protocol will include a single session of breathing 21% oxygen by mask while in the same multi-place chamber. SHAM pressure will go up to 1.2 ATA during the first five minutes of the session (to simulate the pressure sensation in the ears), and then decrease during the next 5 minutes to 1.03 ATA for 55 minutes. 15 minutes after reaching 1.03 ATA and breathing 21% oxygen - IMTP test - For measurement of peak-force at baseline and under the different oxygenation conditions, each participant will be given three attempts at every IMTP test.\n\nA three-minute rest will be given between attempts, with the aim of attaining optimal recovery",[19],"Device: Sham",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Hyperbaric Oxygen Therapy - HBOT","The HYPEROXYGENATED ENVIRONMENT protocol will include a single exposure to hyperoxic environment. The session will last 60 minutes, of 100% oxygen inhalation by mask at 2 ATA",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"The Sham protocol will include a single session of breathing 21% oxygen by mask while in the same multi-place chamber. SHAM pressure will go up to 1.2 ATA during the first five minutes of the session (to simulate the pressure sensation in the ears), and then decrease during the next 5 minutes to 1.03 ATA for 55 minutes",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Eldad mr Yaakobi","CONTACT","972-8-9779393","yaakobi.eldad@gmail.com",[37],{"facility":38,"status":39,"city":40,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":26,"geoPoint":26,"contacts":43},"The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center","RECRUITING","Zrifin","Israel","IL",[44],{"name":45,"role":33,"phone":34,"phoneExt":26,"email":46},"Shai Efrati, MD","efratishai@outlook.com",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Shay Efrati","Professor","100635918","effect-of-hyperoxygenated-environment-on-maximal-muscle-strength-100635918",false,"NCT07558928","Effect of Hyperoxygenated Environment on Maximal Muscle Strength","Effect of Hyperoxygenated Environment on Maximal Muscle Strength in the Mid-thigh Pull Test - a Blinded, Randomized, Sham-Controlled Crossover Study","force","Inclusion Criteria:\n\n1. Healthy\n2. Ages 18-45\n3. Participants are physically active and have a recent resistance-training experience of at least six months, ≥ 3 times a week\n4. Participant willing and able to read, understand and sign an informed consent\n\nExclusion Criteria:\n\n1. Inability to attend scheduled clinic visits or comply with the study protocol\n2. Active malignancy\n3. Active smokers\n4. Previous treatment of hyperbaric chamber for any reason prior to study enrollment.\n5. Chest pathology incompatible with pressure changes\n6. Major orthopedic injury at the past 3 months\n7. Inner ear disease\n8. Lung pathology\n9. Claustrophobia\n10. Previous neurologic conditions (e.g., epilepsy, brain tumors or s\u002Fp neurosurgery etc.)\n11. Comorbidities and medications that rule out the subject",true,"ALL","18 Years","45 Years",{"count":64,"type":65},48,"ESTIMATED","INTERVENTIONAL",[68],"NA","comparing the effect of hyperoxygenated environment on maximal muscle strength in the Mid-thigh Pull Task",[71],"Healthy Lifestyle",[73,74,57,75],"power lifting","gym","imtp","2026-04-26",{"date":78,"type":79},"2026-04-30","ACTUAL",{"date":81,"type":79},"2024-01-01",{"date":83,"type":65},"2027-12-31",{"name":5,"class":6},1]