[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100529006":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":25,"locations":35,"responsibleParty":53,"collaborators":24,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":24,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":24,"enrollmentInfo":65,"targetDuration":24,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":38,"whyStopped":24,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"titrate PEEP","EXPERIMENTAL","individulaized PEEP starting 7cmH2O titrated to best static compliance (Cstat) ranging from 50 -100 cmH2O",[13],"Other: titated PEEP to best static compliance",{"label":15,"type":16,"description":17,"interventionNames":18},"standard","ACTIVE_COMPARATOR","standard PEEP of 5 cmH2O",[13],[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"titated PEEP to best static compliance","the Intraoperative PEEP will be titrated to best static compliance for each patient",[15,9],null,[26,31],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"wessam selima, MD","CONTACT","+201001958858","w.z.selima@med.asu.edu.eg",{"name":32,"role":28,"phone":33,"phoneExt":24,"email":34},"ghada sharafeldin, MSc","+201159296642","ghadasharaf.92@gmail.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":24,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Ain shams university","RECRUITING","Cairo","Cairo Governorate","Egypt","EG",{"type":44,"coordinates":45},"Point",[46,47],31.24967,30.06263,{"lat":47,"lon":46},[50],{"name":51,"role":28,"phone":24,"phoneExt":24,"email":52},"FATHY tash, prof","REC-FMASU@med.asu.edu.eg",{"type":54,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100529006","effect-of-individualized-peep-on-postoperative-pulmonary-complication-in-bariatrics-100529006",false,"NCT06168162","Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics","Effect of Individualized High Positive End-expiratory Pressure on Postoperative Pulmonary Rate in Laparoscopic Bariatric Surgeries","Inclusion Criteria:\n\n* Patients were eligible for participation if the met the following criteria\n\n  * Age between 18 and 60 years old.\n  * Body mass index \\> 40\n  * Laparoscopic bariatric elective surgery under general anesthesia.\n  * ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC.\n\nExclusion Criteria:\n\n* Previous lung surgery\n* ASA status III or IV.\n* Moderate to severe obstructive or restrictive lung disease .\n* Persistant intraoperative hemodynamic instability .\n* Need for postoperative mechanical ventilation",true,"ALL","16 Years",{"count":66,"type":67},50,"ESTIMATED","INTERVENTIONAL",[70],"NA","Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics.\n\nIn this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications",[73,74],"Mechanical Ventilation Pressure High","Bariatric Surgery Candidate",[76],"ventilation","2025-02-14",{"date":79,"type":80},"2025-02-17","ACTUAL",{"date":82,"type":80},"2023-10-01",{"date":84,"type":67},"2025-05-01",{"name":5,"class":6},1]