[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634499":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Adult Patients Undergoing Internal Jugular Vein Catheterization",null,"Adults undergoing elective surgery under general anesthesia who require internal jugular vein catheterization as part of routine clinical care. Intracranial pressure will be assessed noninvasively using optic nerve sheath diameter measurements obtained before and after catheterization.",[13],"Procedure: Internal Jugular Vein Catheterization",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Internal Jugular Vein Catheterization","Internal jugular vein catheterization is performed in patients undergoing major surgical procedures when clinically indicated as part of routine perioperative care. The procedure is not assigned by the study. Additional non-invasive ultrasound measurements, including optic nerve sheath diameter assessment, are obtained to evaluate physiological changes associated with catheterization without altering standard clinical management. Ultrasonography is a non-invasive and safe imaging method routinely used in clinical practice.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Ayça Sultan Şahin, Prof. Dr.","CONTACT","+905323100840","aycasultan@gmail.com",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Aysun Edehan, MD","+905309127017","aysn.997@gmail.com",[31],{"facility":32,"status":10,"city":33,"state":33,"zip":10,"country":34,"countryCode":10,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"University of Health Sciences Kanuni Sultan Suleyman Training and Research Hospital","Istanbul","Turkey (Türkiye)",{"type":36,"coordinates":37},"Point",[38,39],28.94966,41.01384,{"lat":39,"lon":38},[42,44],{"name":43,"role":23,"phone":24,"phoneExt":10,"email":25},"Ayça Sultan Şahin, Prof Dr",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Aysun Edehan","Principal Investigator","100634499","effect-of-internal-jugular-vein-catheterization-on-intracranial-pressure-and-intracranial-blood-flow-100634499",false,"NCT07540481","Effect of Internal Jugular Vein Catheterization on Intracranial Pressure and Intracranial Blood Flow","Effect of Internal Jugular Vein Catheterization on Intracranial Pressure Assessed by Optic Nerve Sheath Diameter and Carotid Doppler Ultrasonography: a Prospective Observational Study","Inclusion Criteria:\n\n* Age ≥18 years\n* Patients undergoing surgery under general anesthesia\n* Patients requiring internal jugular vein catheterization as part of routine clinical care\n* Ability to obtain optic nerve sheath diameter measurements using transorbital ultrasonography\n* Provision of informed consent\n\nExclusion Criteria:\n\n* Known intracranial pathology affecting intracranial pressure\n* Ocular conditions preventing accurate ultrasonographic measurement (e.g., orbital trauma, ocular surgery, infection)\n* Hemodynamic instability\n* Contraindication to internal jugular vein catheterization\n* Inability to obtain adequate ultrasound images","ALL","18 Years",{"count":59,"type":60},61,"ESTIMATED","1 Day","OBSERVATIONAL","This prospective observational study aims to evaluate the effect of internal jugular vein catheterization on intracranial pressure using optic nerve sheath diameter (ONSD) measurements and carotid artery Doppler ultrasonography in adult patients undergoing surgery under general anesthesia.\n\nONSD will be measured noninvasively using transorbital ultrasonography, and carotid Doppler parameters will be assessed at two time points: after endotracheal intubation and approximately 5 minutes after catheterization. The primary objective is to assess short-term changes in ONSD following catheterization.\n\nSecondary objectives include evaluating changes in carotid Doppler measurements and their relationship with ONSD, as well as associations with physiological parameters such as blood pressure, heart rate, oxygen saturation, and end-tidal carbon dioxide.",[65,66],"Intracranial Pressure","Ultrasonography",[68,69,66,70,65,71],"Internal Jugular Vein","Catheterization","Optic Nerve Sheath Diameter","General Anesthesia","NOT_YET_RECRUITING","2026-04-14",{"date":75,"type":76},"2026-04-20","ACTUAL",{"date":78,"type":60},"2026-04-15",{"date":80,"type":60},"2027-03-16",{"name":5,"class":6},1]