[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597156":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":46,"locations":56,"responsibleParty":68,"collaborators":30,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":30,"eligibilityCriteria":76,"healthyVolunteers":73,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":30,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":30,"overallStatus":89,"whyStopped":30,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Medical therapy group","ACTIVE_COMPARATOR","Patients with chronic kidney disease will receive hemodialysis only, for four hours, 3 times per week.",[13],"Other: Hemodialysis",{"label":15,"type":16,"description":17,"interventionNames":18},"intra-dialytic resistive exercise group","EXPERIMENTAL","Patients with chronic kidney disease will receive an intra-dialytic resistance exercise for 12 weeks (3 sessions\u002Fweek) in addition to hemodialysis.",[13,19],"Other: Intradialytic resistive exercise",{"label":21,"type":16,"description":22,"interventionNames":23},"intra-dialytic aerobic exercise group","Patients with chronic kidney disease will receive an intra-dialytic aerobic exercise (leg pedaling) for 12 weeks (3 sessions\u002Fweek) in addition to hemodialysis.",[13,24],"Other: Intradialytic aerobic exercise",[26,31,35],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Hemodialysis","The participants receive hemodialysis for 4 hours, 3 times per week",[9,21,15],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Intradialytic resistive exercise","The participants will receive intradialytic resistive exercise for 12 weeks (3 sessions\u002F week).\n\nDuration: 30 minutes during the first 2 hours of each dialysis session in a recumbent position or seated position.\n\nTime of session: The program starts with a warm-up phase which is 3:5 minutes in the form of light aerobic and stretching exercises for big muscles and ends with a cooling down phase which is 3:5 in the form of light aerobic exercise.\n\nThe resistance exercises include exercises for the big muscles of only the Lower Limbs (LL) muscles of single and multiple-joint which are:1- Knee extensors, 2- Knee flexors, 3- Hip flexors, 4- Hip abductors and adductors. using sandbags of different weights. Sandbag weights are placed on the distal third of the tibia for LL exercises.\n\nIntensity: On the Borg's Scale of Perceived Exertion, which will be measured every 5 minutes during exercise.",[15],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Intradialytic aerobic exercise","Patients with chronic kidney disease will receive an intradialytic aerobic exercise for 12 weeks (3 sessions\u002F week).\n\nDuration: 30 minutes during the first 2 hours of each dialysis session using a stationary bicycle ergometer in a supine position or seated position.\n\nTime of session: The warming up and the cooling down phase consists of 5:10 minutes of slow Pedaling. the main exercise phase consisted of 20 minutes of cycling.\n\nIntensity: The use of the Borg's Scale of Perceived Exertion (RPE) scale enables the intensity of the exercise to be adapted According to the tolerance of each patient.\n\nThe use of the RPE scale enables the intensity of the exercise to be adapted According to the tolerance of each patient, the aim was to obtain between 11 light And 14 somewhat hard.",[21],[40,43],{"name":41,"affiliation":5,"role":42},"Sahier El-Khashab, Professor","STUDY_DIRECTOR",{"name":44,"affiliation":5,"role":45},"Nagwa Badr, Professor","STUDY_CHAIR",[47,52],{"name":48,"role":49,"phone":50,"phoneExt":30,"email":51},"Yasmin Gouda, Master","CONTACT","20 10 08444667","yasmina200068guoda@gmail.com",{"name":53,"role":49,"phone":54,"phoneExt":30,"email":55},"Hend Abd El-Monaem, PHD","+20 11 15507195","Drhendpt@cu.edu.eg",[57],{"facility":58,"status":30,"city":59,"state":30,"zip":30,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":30},"Yasmin Mohamed Mahmoud Gouda","Cairo","Egypt","EG",{"type":63,"coordinates":64},"Point",[65,66],31.24967,30.06263,{"lat":66,"lon":65},{"type":69,"investigatorFullName":58,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Principal investigator","100597156","effect-of-intradialytic-resistance-versus-aerobic-exercise-on-cardiovascular-system-in-patients-on-regular-hemodialysis-100597156",false,"NCT07054827","Effect of Intradialytic Resistance Versus Aerobic Exercise on Cardiovascular System in Patients on Regular Hemodialysis","Inclusion Criteria:\n\n* End-stage renal disease (ESRD) or stage 5 chronic kidney disease (CKD) in which on maintenance regular HD (three sessions\u002Fweek (on alternate days), for four hours\u002Fsession for more than a year to five years when starting the study.\n* Both gender male and female aged from 45 to 60 years old.\n* Patients with intradialytic hypotension sudden drops of systolic pressure of more than 20 mm Hg or diastolic pressure of more than 10 mmHg.\n* Receiving hemodialysis (HD) through uncomplicated arm arteriovenous (A-V) fistula.\n* Patients with Body Mass Index (BMI): 18,5 \\\u003C 30kg\u002Fm2.\n* In a stable medical, clinical, and hemodynamic condition\n* Untrained at baseline and did not participate in any regular physical activity before.\n\nExclusion Criteria:\n\n* Severe Chest diseases (either obstructive or restrictive).\n* Clinical signs of a severe cardiac event. (eg, severe atherosclerosis, congestive heart failure),\n* Severe psychiatric or cognitive impairment, who unable to follow comment.\n* Neurological disorders affecting respiratory muscles or any muscular dystrophies (cervical disc or bulge).\n* Patients with severe self-limiting illness (e.g., cancer).\n* Patients with Body Mass Index (BMI) \\> 30kg\u002Fm2.\n* Previous renal transplantation patients.\n* Pregnant females or became pregnant during the study.\n* Patients started HD in less than a year or more than 5 years.\n* Hospitalized during the prior month.\n* Patients who were irregular in HD or not adherent to the exercise program.","FEMALE","45 Years","65 Years",{"count":81,"type":82},75,"ESTIMATED","INTERVENTIONAL",[85],"NA","The purpose of the study is to compare the effect of resistance exercise and aerobic exercise on intradialytic hypotension in patients undergoing hemodialysis.",[88],"Hemodialysis Complication","NOT_YET_RECRUITING","2025-06-28",{"date":92,"type":93},"2025-07-08","ACTUAL",{"date":95,"type":82},"2025-07-05",{"date":97,"type":82},"2025-11-20",{"name":5,"class":6},1]