[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100420515":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":44,"centralContacts":48,"locations":57,"responsibleParty":81,"collaborators":10,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":10,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":10,"studyType":98,"phases":10,"briefSummary":99,"conditions":100,"keywords":10,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Marshall University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Beta blockade",null,"Beta blocker (labetalol or atenolol) will be given for a cardiac output \\>8 l\u002Fmin.",[13,14],"Drug: Labetalol","Drug: Atenolol",{"label":16,"type":10,"description":17,"interventionNames":18},"Nifedipine","Nifedipine will be given for a mean arterial pressure \\>100.",[19],"Drug: Nifedipine",[21,29,34],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Labetalol","Beta blocker",[9],[27,28],"Normodyne","Trandate",{"type":22,"name":30,"description":24,"armGroupLabels":31,"otherNames":32},"Atenolol",[9],[33],"Tenormin",{"type":22,"name":16,"description":35,"armGroupLabels":36,"otherNames":37},"Calcium channel blocker",[16],[38,39,40,41,42,43],"Adalat CC","Afeditab CR","Nifediac CC","Nifedical XL","Procardia","Procardia XL",[45],{"name":46,"affiliation":5,"role":47},"Jesse Cottrell, MD","PRINCIPAL_INVESTIGATOR",[49,54],{"name":50,"role":51,"phone":52,"phoneExt":10,"email":53},"Morgan Ruley, MS","CONTACT","(304) 691-1458","kelley115@marshall.edu",{"name":46,"role":51,"phone":55,"phoneExt":10,"email":56},"(304) 691-1400","cottrellje@marshall.edu",[58],{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Maternal Hypertension Center at Cabell Huntington Hospital","RECRUITING","Huntington","West Virginia","25701","United States","US",{"type":67,"coordinates":68},"Point",[69,70],-82.44515,38.41925,{"lat":70,"lon":69},[73,75,77,78],{"name":46,"role":51,"phone":74,"phoneExt":10,"email":56},"3046911400",{"name":50,"role":51,"phone":76,"phoneExt":10,"email":53},"3046911458",{"name":46,"role":47,"phone":10,"phoneExt":10,"email":10},{"name":79,"role":80,"phone":10,"phoneExt":10,"email":10},"David Chaffin, MD","SUB_INVESTIGATOR",{"type":47,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jesse Cottrell","Assistant Professor","100420515","effect-of-labetalol-atenolol-and-nifedipine-on-maternal-hemodynamics-measured-by-icg-in-early-pregnancy-100420515",false,"NCT04755764","Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy","The Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by Impedance Cardiography in Early Pregnancy","Inclusion Criteria:\n\n* Patients presenting to Maternal Hypertension Center at Cabell Huntington Hospital\n* English speaking\n* 18-45 years old.\n* Willing to provide informed consent\n* Gestational age prior to 15 weeks gestation\n\nExclusion Criteria:\n\n* Non-English speaking patients, patients\n* \\\u003C18 years old or \\>45 years old\n* Not willing or able to provide consent\n* Gestational age \\>15 weeks",true,"FEMALE","18 Years","45 Years",{"count":96,"type":97},60,"ESTIMATED","OBSERVATIONAL","The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy. Patients will be given medication based on their hemodynamics and asked to return for a repeat measurement.",[101,102,103,104,105],"Systolic Hypertension","Pregnancy Related","Diastolic Hypertension","Cardiac Output, Low","Cardiac Output, High","2025-05-09",{"date":108,"type":109},"2025-05-13","ACTUAL",{"date":111,"type":109},"2021-03-03",{"date":113,"type":97},"2025-12",{"name":5,"class":6},1]