[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575325":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":10,"responsibleParty":25,"collaborators":10,"id":28,"slug":29,"hasResults":30,"nctId":31,"briefTitle":32,"officialTitle":32,"acronym":33,"eligibilityCriteria":34,"healthyVolunteers":35,"sex":36,"minAge":37,"maxAge":38,"enrollmentInfo":39,"targetDuration":10,"studyType":42,"phases":10,"briefSummary":43,"conditions":44,"keywords":46,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":10},{"fullName":5,"class":6},"Aydin Adnan Menderes University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"erector spina plan block",null,"ESP block will be applied from the midline 3 cm lateral to the T5 level under ultrasound guidance. After the area is cleaned with povidone iodine before the block, the T5 transverse process will be determined using a linear ultrasound probe. Local anesthetic will be applied between the transverse process and the erector spinae muscle with the help of an insulated needle designed for peripheral block procedures. The location of the needle will be verified with the hydrodissection method with physiological serum without local anesthesia. After the location of the needle is verified, 0.25% bupivacaine 20 ml mixture will be applied.",[13],"Other: Echocardiography",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Echocardiography","HR, MAP, SBP and DBP will be recorded at baseline and 15 minutes after ESP block. Cardiac output (CO) will be calculated using echocardiographic data on stroke volume (SV) (measured from the LV outflow tract) and multiplied by HR. Changes in LV systolic function will be assessed with three parameters: fractional shortening (FS), ejection fraction (EF) using the Simpson method and S' wave of tissue Doppler imaging (TDI) of the mitral annulus (average of values at the medial and lateral annulus). LV diastolic function will be assessed with three parameters and interpreted according to the European Association of Cardiovascular Imaging guidelines. Pulsed wave (PW) Doppler of trans-mitral flow will be used to obtain the ratio between early (e) and late (atrial, a) waves. A PW Doppler between the LV outflow tract and the mitral valve will be performed to estimate the iso-volumetric relaxation time IVRT. TDI will be used to investigate myocardial relaxation at the mitral annular level (ear",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"ferdi gülaştı","CONTACT","+905054929650","ferdigulasti@gmail.com",{"type":26,"investigatorFullName":21,"investigatorTitle":27,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","ass. prof.dr","100575325","effect-of-left-erector-spinae-plane-block-on-left-ventricular-functions-100575325",false,"NCT06770816","Effect of Left Erector Spinae Plane Block on Left Ventricular Functions","ESP-LV ECHO","Inclusion Criteria:\n\nPatients undergoing elective left-sided thoracic surgery ASA I-III 18-75 years of age\n\nExclusion Criteria:\n\n1. Refusal at enrollment\n2. Request for withdrawal from the study\n3. Inability to give informed consent\n4. Emergency surgery\n5. Bleeding diathesis\n6. Presence of contraindications to the LA agents used in this study\n7. Use of chronic opioids\n8. Psychiatric disorders\n9. Presence of infection at the injection site",true,"ALL","18 Years","75 Years",{"count":40,"type":41},23,"ESTIMATED","OBSERVATIONAL","Many studies have shown a decrease in inotropic status (intrinsic function) after blockade of cardiac sympathetic innervation with thoracic epidural anesthesia (TEA) (4,5). There is no study in the literature investigating the cardiac effects of left thoracic ESP block. We think that left thoracic ESP block, like TEA, may also have cardiac effects. Therefore, we aimed to investigate the effect of left thoracic ESP block on left ventricular functions with transthoracic echocardiography (TTE).",[45,16],"Erector Spina Plan Block",[9,47,48],"left ventricle","echocardiography","NOT_YET_RECRUITING","2025-01-07",{"date":52,"type":53},"2025-01-13","ACTUAL",{"date":55,"type":41},"2025-01-10",{"date":57,"type":41},"2026-02-02",{"name":5,"class":6}]