[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642474":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":24,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":24,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":24,"overallStatus":37,"whyStopped":24,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"General Hospital of Ningxia Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lidocaine","EXPERIMENTAL","Lidocaine is administered via a gastric tube.",[13],"Procedure: Lidocaine",{"label":15,"type":10,"description":16,"interventionNames":17},"Normal Saline","Administer normal saline through the gastric tube.",[18],"Procedure: Normal Saline (0.9% NaCl)",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Upon completion of the surgery and before extubation, 20 ml of 0.5% lidocaine should be administered through the pre - inserted orogastric tube. The gastric tube should be clamped for 5 minutes to ensure sufficient mucosal exposure, and then removed before extubation.",[9],null,{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Normal Saline (0.9% NaCl)","Before extubation after the surgery is completed, administer 20 ml of normal saline through the pre - inserted orogastric tube. Clamp the gastric tube for 5 minutes to ensure sufficient mucosal exposure, and then remove the tube before extubation.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Siying He","CONTACT","+86 18209610221","1342850868@qq.com",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Yinchuan","Ningxia","750000","China","CN",{"type":44,"coordinates":45},"Point",[46,47],106.27306,38.46806,{"lat":47,"lon":46},[50],{"name":5,"role":32,"phone":51,"phoneExt":24,"email":34},"+86-0951-4091488",{"type":53,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100642474","effect-of-lidocaine-through-gastric-tube-on-ponv-100642474",false,"NCT07643298","Effect of Lidocaine Through Gastric Tube on PONV","Effect of Lidocaine Applied Via Nasogastric Tube on Postoperative Nausea and Vomiting in Obese Patients Undergoing Bariatric Surgery","Inclusion Criteria:\n\n* Adults aged between 18 and 65 years old;\n* American Society of Anesthesiologists (ASA) physical status classification II - III;\n* Planned to undergo primary elective laparoscopic sleeve gastrectomy with general anesthesia;\n* Capable of giving informed consent.\n\nExclusion Criteria:\n\n* Known allergy, hypersensitivity or contraindication to lidocaine or amide - type local anesthetics;\n* Previous significant liver or kidney dysfunction (e.g., ALT\u002FAST \\> 3 times the upper limit of normal, GFR \\\u003C 30 mL\u002Fmin);\n* History of epilepsy, cardiac conduction abnormalities or previous diagnosis of malignant hyperthermia;\n* Pregnancy or lactation;\n* Patients who received systemic lidocaine treatment during the operation;\n* History of severe postoperative nausea and vomiting (PONV) or motion sickness, requiring multiple prophylactic medications;\n* Emergency or revision bariatric surgery.","ALL","18 Years","65 Years",{"count":65,"type":66},100,"ESTIMATED","INTERVENTIONAL",[69],"NA","The goal of this clinical trial is to learn if intragastric administration of lidocaine can reduce postoperative nausea and vomiting in obese patients undergoing laparoscopic sleeve gastrectomy. The main question it aims to answer is:\n\nDoes administering 0.5% lidocaine via an orogastric tube reduce the incidence of postoperative nausea and vomiting (PONV) in the post-anesthesia care unit and within the first 24 hours after surgery compared to a placebo (normal saline)?\n\nResearchers will compare the Lidocaine Group to the Placebo Group to see if the intervention lowers the PONV incidence.\n\nParticipants will:\n\n* Receive the assigned study solution (either 0.5% lidocaine 20ml or normal saline 20ml) through an orogastric tube upon surgery completion and before extubation.\n* Have their gastric tube clamped for 5 minutes to ensure mucosal exposure before removal.\n* Undergo standardized total intravenous anesthesia and perioperative management according to the study protocol.\n* Be assessed for nausea, vomiting, and other outcomes at specified time points postoperatively in the recovery room and at 6, 12, and 24 hours.",[72],"PONV","2026-06-09",{"date":75,"type":76},"2026-06-11","ACTUAL",{"date":78,"type":76},"2026-05-20",{"date":80,"type":66},"2027-06-30",{"name":5,"class":6},1]