[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629495":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":29,"locations":29,"responsibleParty":36,"collaborators":29,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":29,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":29,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":69,"whyStopped":29,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":29},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"50 rpm Biological Drilling","EXPERIMENTAL","Implant osteotomy will be performed using low-speed biological drilling at 50 rpm without irrigation. Bone particles produced during drilling will be collected for evaluation of osteogenic potential.",[13],"Procedure: Implant osteotomy using biological drilling at 50 rpm without irrigation.",{"label":15,"type":10,"description":16,"interventionNames":17},"150 rpm Biological Drilling","Implant osteotomy will be performed using biological drilling at 150 rpm without irrigation. Autogenous bone particles generated during drilling will be collected and analyzed for osteogenic potential.",[18],"Procedure: Implant osteotomy using biological drilling at 150 rpm without irrigation.",{"label":20,"type":10,"description":21,"interventionNames":22},"300 rpm Biological Drilling","Implant osteotomy will be performed using biological drilling at 300 rpm without irrigation with collection of autogenous bone particles for laboratory analysis.",[23],"Procedure: Implant osteotomy using biological drilling at 300 rpm without irrigation.",[25,30,33],{"type":26,"name":27,"description":11,"armGroupLabels":28,"otherNames":29},"PROCEDURE","Implant osteotomy using biological drilling at 50 rpm without irrigation.",[9],null,{"type":26,"name":31,"description":16,"armGroupLabels":32,"otherNames":29},"Implant osteotomy using biological drilling at 150 rpm without irrigation.",[15],{"type":26,"name":34,"description":21,"armGroupLabels":35,"otherNames":29},"Implant osteotomy using biological drilling at 300 rpm without irrigation.",[20],{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Radwa Amr","Dr","100629495","effect-of-mandibular-drilling-speed-on-implant-stability-and-osteogenic-potential-a-randomized-clinical-trial-100629495",false,"NCT07475416","Effect of Mandibular Drilling Speed on Implant Stability and Osteogenic Potential: A Randomized Clinical Trial","Impact of Mandibular Biological Drilling Speeds on Implant Stability and Osteogenic Potential of Autogenous Bone Particles: A Randomized Clinical Trial","Inclusion Criteria:\n\nAdult patients requiring single dental implant placement in the mandible\n\nAdequate bone volume for implant placement without need for bone grafting\n\nGood general health\n\nAbility to provide informed consent\n\nExclusion Criteria:\n\nSystemic diseases affecting bone metabolism or healing\n\nHistory of radiotherapy in the head and neck region\n\nUncontrolled diabetes mellitus\n\nActive periodontal disease\n\nHeavy smoking\n\nPregnancy or lactation","ALL","20 Years","60 Years",{"count":51,"type":52},36,"ESTIMATED","INTERVENTIONAL",[55],"NA","This randomized clinical trial aims to evaluate the effect of different low-speed biological drilling protocols on implant stability and the osteogenic potential of autogenous bone particles collected during implant osteotomy. Patients requiring single dental implant placement in the mandible will be randomly assigned to different drilling speed protocols without irrigation. Implant stability will be measured clinically, while collected bone particles will be analyzed for osteogenic markers. The study aims to determine whether biological drilling improves implant stability and preserves the regenerative potential of autogenous bone.",[58,59],"Edentulism","Tooth Loss",[61,62,63,64,65,66,67,68],"biological drilling","low speed drilling","dental implants","implant stability","autogenous bone particals","BMP-2","VEGF","mandibular implants","NOT_YET_RECRUITING","2026-03-11",{"date":72,"type":73},"2026-03-16","ACTUAL",{"date":75,"type":52},"2026-03-15",{"date":77,"type":52},"2027-04-01",{"name":5,"class":6}]