[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643222":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":42,"collaborators":12,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":12,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":12,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":12,"overallStatus":64,"whyStopped":12,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"University of Baghdad","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","NO_INTERVENTION","receive routine care",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention Group","EXPERIMENTAL","participants in the intervention group will receive digital support aimed at improving their adherence to prescribed medications. This support will include a smartphone application developed specifically for the study, as well as reminder messages via WhatsApp to prompt participants to take their levothyroxine at the scheduled times",[18],"Other: medication adherence based digital intervention",[20],{"type":6,"name":21,"description":16,"armGroupLabels":22,"otherNames":23},"medication adherence based digital intervention",[14],[24],"intervntion group",[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Shahad Sabah Khudhair","CONTACT","9647737721360","shahed.sabbah1202a@conursing.uobaghdad.edu.iq",[32],{"facility":5,"status":12,"city":33,"state":12,"zip":12,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":12},"Baghdad","Iraq","IQ",{"type":37,"coordinates":38},"Point",[39,40],44.40088,33.34058,{"lat":40,"lon":39},{"type":43,"investigatorFullName":27,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","PhD Student","100643222","effect-of-medication-adherence-based-digital-intervention-on-fatigue-severity-weight-and-thyroid-hormone-regulation-100643222",false,"NCT07636681","Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation","Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation in Patients With Hypothyroidism: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults (≥18 years) with primary hypothyroidism.\n* On stable levothyroxine therapy for at least 3 months.\n* Able to read, understand study instructions\n* capable of using basic mobile applications\n* poor medication adherence, clinically significant fatigue, documented weight fluctuations and abnormal thyroid hormone\n\nExclusion Criteria:\n\n* Secondary hypothyroidism or recent thyroidectomy\u002Fradioactive iodine therapy.\n* Pregnancy or breastfeeding woman.\n* Severe psychiatric disorders or cognitive impairment\n* significant visual or hearing deficits\n* Serious comorbidities affecting medication adherence (e.g., chronic disease, renal, or hepatic disease).\n* take dietary supplements or medications that interfere with levothyroxine absorption.","ALL","18 Years","60 Years",{"count":56,"type":57},80,"ESTIMATED","INTERVENTIONAL",[60],"NA","1. To evaluate the effect of a medication adherence-based digital intervention on fatigue severity in patients with hypothyroidism.\n2. To assess the effect of a medication adherence-based digital intervention on weight in patients with hypothyroidism.\n3. To investigate the effect of a medication adherence-based digital intervention on thyroid hormone regulation in patients with hypothyroidism.",[63],"Hypothyroidism","NOT_YET_RECRUITING","2026-06-03",{"date":67,"type":68},"2026-06-09","ACTUAL",{"date":70,"type":57},"2026-06-01",{"date":72,"type":57},"2026-12-30",{"name":5,"class":6},1]