[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626670":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":11,"centralContacts":34,"locations":40,"responsibleParty":59,"collaborators":11,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":11,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":11,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":43,"whyStopped":11,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Kasr El Aini Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Mediterranean Diet (MD)","ACTIVE_COMPARATOR",null,[13],"Other: Mediterranean Diet (MD)",{"label":15,"type":10,"description":11,"interventionNames":16},"Paleolithic Diet (PD)",[17],"Other: Paleolithic Diet (PD)",{"label":19,"type":20,"description":11,"interventionNames":21},"Control (usual diet)","PLACEBO_COMPARATOR",[22],"Other: Control (Usual Diet)",[24,27,30],{"type":6,"name":9,"description":25,"armGroupLabels":26,"otherNames":11},"Participants will follow a Mediterranean diet for 12 weeks, emphasizing fruits, vegetables, whole grains, legumes, fish, and olive oil, with limited red meat and processed foods. Nutritional counseling and meal plans will be provided.",[9],{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":11},"Participants will follow a Paleolithic diet for 12 weeks, focusing on lean meats, fish, fruits, vegetables, eggs, nuts, and seeds, while excluding grains, legumes, dairy, processed foods, refined sugars, and added salt. Nutritional counseling and meal plans will be provided.",[15],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":11},"Control (Usual Diet)","Participants will continue their habitual diet without specific dietary modifications. General healthy eating advice may be provided.",[19],[35],{"name":36,"role":37,"phone":38,"phoneExt":11,"email":39},"Gehad Maghraby, MD","CONTACT","+201027491363","gehad.maghraby@kasralainy.edu.eg",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Kasr Al Ainy Hospital, Faculty of Medicine, Cairo University","RECRUITING","Cairo","Al-Manial","11956","Egypt","EG",{"type":50,"coordinates":51},"Point",[52,53],31.24967,30.06263,{"lat":53,"lon":52},[56],{"name":57,"role":37,"phone":58,"phoneExt":11,"email":39},"Gehad Maghraby, M.D.","+201027491361",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Gehad Maghraby","Lecturer at Internal Medicine Department, Rheumatology and Clinical Immunology Division, Faculty of Medicine, Cairo University","100626670","effect-of-mediterranean-vs-paleolithic-diet-on-ra-activity-sarcopenia-and-qol-12-week-rct-100626670",false,"NCT07438652","Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT","Effect of Mediterranean and Paleolithic Dietary Interventions on Nutritional Status, Disease Activity, Sarcopenia, and Quality of Life in Adults With Rheumatoid Arthritis: A 12-Week Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients classified as having rheumatoid arthritis according to the 2010 rheumatoid arthritis ACR\u002F EULAR classification criteria with a selected age group of 40 to 60 years old.\n\nExclusion Criteria:\n\n* Patients with comorbidities (e.g., diabetes mellitus, hypertension, gout, thyroid dysfunction).","ALL","40 Years","60 Years",{"count":74,"type":75},75,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study aims to evaluate the effects of Mediterranean and Paleolithic dietary interventions on nutritional status, disease activity, fatigue, sleep, and quality of life in adults with rheumatoid arthritis (RA). Participants aged 40-60 years will be randomly assigned to follow either a Mediterranean diet, a Paleolithic diet, or continue their usual diet for 12 weeks. The study will assess anthropometric measurements, disease activity score (DAS28), laboratory biomarkers (CBC, CRP, ESR, lipid profile, fasting glucose, HbA1c), and patient-reported outcomes. The trial will determine whether these diets improve RA management and overall well-being.",[81],"Rheumatoid Arthritis (RA)",[83,84,85,86,87,88,89],"Dietary Intervention","Rheumatoid arthritis","Paleolitic Diet","Mediterranean Diet","Sarcopenia","Quality of life","Nutrition","2026-02-22",{"date":92,"type":93},"2026-02-27","ACTUAL",{"date":95,"type":93},"2026-01-17",{"date":97,"type":75},"2026-07-15",{"name":5,"class":6},1]