[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625830":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":38,"locations":48,"responsibleParty":60,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":26,"overallStatus":81,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Cairo University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Monochromatic Infrared Energy therapy group","EXPERIMENTAL","15 patients will receive Monochromatic Infrared Energy (MIRE) therapy in addition to standard wound care.",[13,14],"Device: Monochromatic Infrared Energy therapy","Other: Standard wound care",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard wound care group","ACTIVE_COMPARATOR","15 patients will receive standard wound care only.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Monochromatic Infrared Energy therapy","Patients will receive Monochromatic Infrared Energy (MIRE) therapy in addition to standard wound care. Intervention will be applied for 3 times a week for 6 consecutive weeks.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard wound care","Patients will receive standard wound care only, which will include wound debridement, infection control, and glucose management.",[9,16],[32,35],{"name":33,"affiliation":5,"role":34},"Marwa Mahdy, PHD","STUDY_DIRECTOR",{"name":36,"affiliation":5,"role":37},"Amal Abd El-Baky, Professor","STUDY_CHAIR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":26,"email":43},"Fatma Sayed, Master","CONTACT","01147854238","fatmamohamed10796@gmail.com",{"name":45,"role":41,"phone":46,"phoneExt":26,"email":47},"Mohamed youssed, Professor","01111770810","mdrmohtaha@gmail.com",[49],{"facility":50,"status":26,"city":51,"state":26,"zip":26,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":26},"Fatma Mohamed Sayed","Cairo","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],31.24967,30.06263,{"lat":58,"lon":57},{"type":61,"investigatorFullName":50,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Principal investigator","100625830","effect-of-monochromatic-infrared-energy-on-healing-of-diabetic-foot-ulcers-100625830",false,"NCT07427732","Effect of Monochromatic Infrared Energy on Healing of Diabetic Foot Ulcers","Inclusion Criteria:\n\n* Diagnosis of Diabetes Mellitus: Participants must have a confirmed diagnosis of Type 1 or Type 2 diabetes.\n* Presence of a Diabetic Foot Ulcer (DFU): Participants must have a current diabetic foot ulcer, typically classified as Wagner grade 1 or 2 (superficial or deep ulcers without bone involvement).\n* Ulcer Duration: The diabetic ulcer must be chronic, generally defined as a wound that has not healed within 30 days.\n* Adequate Circulation: Participants must have sufficient blood flow to the affected limb as confirmed by non-invasive vascular tests (e.g., Ankle-Brachial Index or Doppler ultrasound).\n* Ability to Consent: Participants must be able to provide informed consent and agree to comply with study protocols, including regular clinic visits for treatment and assessments.\n\nExclusion Criteria:\n\n* Active Infection or Osteomyelitis: Presence of an active infection at the ulcer site or underlying bone infection (osteomyelitis).\n* Wagner Grade 3 or Higher: Participants with more severe ulcers, such as those extending to bone or involving gangrene, will be excluded.\n* Severe Peripheral Arterial Disease (PAD): Participants with severe ischemia, as indicated by an Ankle-Brachial Index (ABI) below a certain threshold (e.g., \\\u003C 0.5), will be excluded.\n* Use of Other Phototherapy Modalities: Participants currently receiving other forms of phototherapy, including low-level laser therapy (LLLT), will not be eligible.\n* Recent Surgery on the Affected Limb: Participants who have undergone recent surgical procedures on the ulcerated limb within the last 30 days.\n* Pregnancy: Pregnant individuals will be excluded due to the potential unknown effects of MIRE on fetal development.\n* Non-compliance Risk: Participants who are deemed unable to comply with the study protocol or follow-up schedule, due to cognitive impairment, substance abuse, or other factors.\n* Other Severe Comorbidities: Patients with severe comorbid conditions such as terminal illness or uncontrolled cardiovascular disease that may interfere with wound healing or study participation.","ALL","40 Years","70 Years",{"count":73,"type":74},40,"ESTIMATED","INTERVENTIONAL",[77],"NA","The purpose of this study is to evaluate the effectiveness of monochromatic infrared energy (MIRE) as an adjunctive therapy for the healing of diabetic foot ulcers (DFUs).",[80],"Diabetic Foot Ulcer","NOT_YET_RECRUITING","2026-02-20",{"date":84,"type":85},"2026-02-24","ACTUAL",{"date":87,"type":74},"2026-02-22",{"date":89,"type":74},"2026-04-27",{"name":5,"class":6},1]