[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631355":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":32,"locations":42,"responsibleParty":59,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Inonu University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","ACTIVE_COMPARATOR","Patients in this group receive scaling and root planing (SRP) only.",[13],"Procedure: Scaling and Root Planing",{"label":15,"type":16,"description":17,"interventionNames":18},"Test Group","EXPERIMENTAL","Patients in this group receive scaling and root planing (SRP) followed by the use of Morus nigra mouthwash twice daily for 14 days",[13,19],"Dietary Supplement: Morus Nigra Mouthwash",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Scaling and Root Planing","Mechanical removal of dental plaque and calculus from the tooth surfaces",[9,15],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DIETARY_SUPPLEMENT","Morus Nigra Mouthwash","Morus nigra extract based mouthwash, used 2 times a day for 14 days",[15],[33,38],{"name":34,"role":35,"phone":36,"phoneExt":26,"email":37},"Omer Alperen Kırmızıgul, Assistant Professor","CONTACT","+905073951987","alperen.kirmizigul@inonu.edu.tr",{"name":39,"role":35,"phone":40,"phoneExt":26,"email":41},"Burak Koçak, Dds","+9005446609444","kocakburak44@gmail.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":26,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Inonu University Faculty of Dentistry","RECRUITING","Battalgazi","Malatya","44300","Turkey (Türkiye)",{"type":51,"coordinates":52},"Point",[53,54],38.3585,38.42286,{"lat":54,"lon":53},[57],{"name":58,"role":35,"phone":36,"phoneExt":26,"email":37},"Omer Alperen Kırmızıgul",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Ömer Alperen Kırmızıgül","Assistant Professor","100631355","effect-of-morus-nigra-mouthwash-on-gingivitis-treatment-100631355",false,"NCT07499596","Effect of Morus Nigra Mouthwash on Gingivitis Treatment","Evaluation of the Efficacy of Morus Nigra Mouthwash as an Adjunct to Scaling and Root Planing in the Treatment of Gingivitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of generalized gingivitis (Gingival Index \\> 1).\n* Presence of at least 20 natural teeth.\n* Systemically healthy individuals.\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Smoking or use of tobacco products.\n* Presence of periodontitis (no clinical attachment loss).\n* Use of antibiotics or anti-inflammatory drugs in the last 6 months.\n* Pregnancy or lactation.\n* History of allergy to Morus nigra or mouthwash components.\n* Systemic diseases (Diabetes, cardiovascular diseases, etc.).","ALL","18 Years","65 Years",{"count":74,"type":75},30,"ESTIMATED","INTERVENTIONAL",[78],"NA","The aim of this study is to evaluate the clinical, microbiological, and biochemical effects of Morus nigra (black mulberry) mouthwash when used as an adjunct to non-surgical periodontal treatment (scaling and root planing - SRP) in patients with generalized gingivitis. Participants will be randomly assigned to two groups: one receiving SRP only, and the other receiving SRP plus Morus nigra mouthwash twice daily for 14 days. Clinical parameters, cytokine levels in gingival crevicular fluid (TNF-alpha, IL-1beta, IL-10), and subgingival bacterial load will be assessed at baseline, 1 month, and 3 months.",[81],"Gingivitis",[83,84,85],"Morus nigra","Mouthwash","Cytokines","2026-04-08",{"date":88,"type":89},"2026-04-13","ACTUAL",{"date":91,"type":89},"2026-01-15",{"date":93,"type":75},"2026-07-15",{"name":5,"class":6},1]