[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628641":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":52,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":25,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":25,"overallStatus":76,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1: Deep Neuromuscular Block","EXPERIMENTAL","Deep Neuromuscular Block: Rocuronium titrated according to quantitative neuromuscular monitoring \\[Post-Tetanic count (PTC): ≥1; Train of Four (TOF) Count: 0\\]",[13],"Drug: Rocuronium",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm 2: Moderate Neuromuscular Block","ACTIVE_COMPARATOR","Moderate Neuromuscular Block: Rocuronium titrated according to quantitative neuromuscular monitoring \\[Train of Four (TOF) Count: 1-3\\]",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Rocuronium","Rocuronium will be administered intravenously as bolus and continuous infusion to achieve target neuromuscular blockade depth according to group allocation. Neuromuscular function will be monitored using quantitative TOF monitoring.",[9,15],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Kubilay G YILMAZ","CONTACT","+90 537 274 16 72","kgyilmaz91@gmail.com",[33],{"facility":34,"status":25,"city":35,"state":36,"zip":37,"country":38,"countryCode":25,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Ankara Bilkent City Hospital","Ankara","Çankaya","06530","Turkey (Türkiye)",{"type":40,"coordinates":41},"Point",[42,43],32.85427,39.91987,{"lat":43,"lon":42},[46,50],{"name":47,"role":29,"phone":48,"phoneExt":25,"email":49},"İsmail AYTAÇ, Associate Professor","+90 505 634 03 69","aytacismail1972@gmail.com",{"name":47,"role":51,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":51,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"ismail aytaç","Associate Professor","100628641","effect-of-neuromuscular-block-depth-on-driving-pressure-and-postoperative-respiratory-events-in-abdominal-surgeries-100628641",false,"NCT07464288","Effect of Neuromuscular Block Depth on Driving Pressure and Postoperative Respiratory Events in Abdominal Surgeries","The Effect of Different Depths of Neuromuscular Blockade, Assessed by Train of Four (TOF) Monitoring, On Driving Pressure and the Development of Postoperative Critical Respiratory Events in Abdominal Surgeries","Inclusion Criteria:\n\n* Elective abdominal surgery under general anesthesia that is expected to last longer than one hour\n* ASA I-II-III\n* Age ≥18 years\n* Written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* ASA ≥ IV\n* Age \\\u003C18\n* Obesity (BMI\\>30) and cachexia (BMI \\\u003C18)\n* Laparoscopic surgery\n* Emergency procedure\n* Allergy to drugs used during induction and maintenance of general anesthesia\n* Presence of psychiatric\u002Fneurologic\u002Fneuromuscular disease\n* Risk of malignant hyperthermia or having any relative with history of malignant hyperthermia\n* Use of medications that may affect neuromuscular function (anticonvulsants, aminoglycosides, magnesium salts, etc.)\n* Pregnancy\n* Presence of advanced chronic lung disease (asthma, COPD, etc.)\n* Presence of advanced liver and renal disease (creatinine\\>1.6, liver function tests above twice the normal range)",true,"ALL","18 Years",{"count":66,"type":67},128,"ESTIMATED","INTERVENTIONAL",[70],"NA","This randomized controlled study aims to evaluate the effects of deep versus moderate neuromuscular blockade on intraoperative driving pressure and the development of postoperative critical respiratory events in patients undergoing abdominal surgery under general anesthesia.",[73,74,75],"Driving Pressure","Neuromuscular Blockade Monitoring","Postoperative Respiratory Complications","NOT_YET_RECRUITING","2026-03-15",{"date":79,"type":80},"2026-03-17","ACTUAL",{"date":82,"type":67},"2026-03-23",{"date":84,"type":67},"2026-04-24",{"name":5,"class":6},1]