[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499339":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":44,"collaborators":49,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":72,"whyStopped":11,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":11},{"fullName":5,"class":6},"Jinling Hospital, China","OTHER",[8,15,19,25],{"label":9,"type":10,"description":11,"interventionNames":12},"high protein + early bedside rehabilitation","EXPERIMENTAL",null,[13,14],"Dietary Supplement: high protein","Behavioral: rehabilitation",{"label":16,"type":17,"description":11,"interventionNames":18},"high protein alone","ACTIVE_COMPARATOR",[13],{"label":20,"type":21,"description":22,"interventionNames":23},"standard protein + early bedside","PLACEBO_COMPARATOR","standard protein and rehabilitation",[14,24],"Dietary Supplement: standard protein",{"label":26,"type":27,"description":28,"interventionNames":29},"standard protein","SHAM_COMPARATOR","only standard protein",[24],[31,36,41],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":11},"DIETARY_SUPPLEMENT","high protein","Patients in high-protein group will be given a target protein amount of 2.0 g\u002Fkg\u002Fd. Standard enteral nutrition is the first choice,the remaining target value will be met by intravenous amino acid infusion.",[9,16],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":11},"BEHAVIORAL","rehabilitation","In this trial, the investigator will provide early rehabilitation treatment such as respiratory training, bicycle training, and medium frequency electrical stimulation to patients.",[9,20],{"type":32,"name":26,"description":42,"armGroupLabels":43,"otherNames":11},"The investigator set a protein target of 1.2 g\u002FKg\u002Fd for the standard protein group, which will be supplied enterally or parenterally.",[26,20],{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":48,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Yao Wei,MD","associate chief physician","The First Affiliated Hospital of Soochow University",[50],{"name":48,"class":6},"100499339","effect-of-nutritional-support-and-early-rehabilitation-on-sepsis-100499339",false,"NCT05781971","Effect of Nutritional Support and Early Rehabilitation on Sepsis","Department of Intensive Care Medicine, The First Affiliated Hospital of Soochow University","NUSPOTER","Inclusion Standard\n\n1. Patients with sepsis\n2. Patients aged 18-70 years\n3. Time of admission ≤48 h\n4. Non-terminal condition\n\nExclusion Standard\n\n1. Severe acute kidney injury\n2. Severe chronic liver disease (MELD score ≥20) or acute hepatic failure\n3. Protein allergy\n4. Pregnancy and lactation\n5. BMI≥30 kg\u002Fm²","ALL","18 Years","80 Years",{"count":63,"type":64},1600,"ESTIMATED","INTERVENTIONAL",[67],"NA","Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a short time.This pathology frequently leads to prolonged hospitalization and mechanical ventilation, increased mortality, and reduced quality of survival.It is uncertainty whether sepsis patients in ICU can benefit from high protein intake combined with early exercise. Even though the combination has been shown to be beneficial in other populations.In the present study, the investigator will evaluate the effects of a combination of high protein targets combined with early rehabilitation in sepsis patients in ICU.",[70,71],"Life Quality","Hospital Mortality","NOT_YET_RECRUITING","2024-06-14",{"date":75,"type":76},"2024-06-17","ACTUAL",{"date":78,"type":64},"2024-12-01",{"date":80,"type":64},"2026-05",{"name":5,"class":6}]