[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497121":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":32,"locations":40,"responsibleParty":56,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":80,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Chelsea and Westminster NHS Foundation Trust","OTHER",[8,11,14,19],{"label":9,"type":10,"description":9,"interventionNames":10},"Pregnant women with obesity\u002FGDM\u002FT2DM",null,{"label":12,"type":10,"description":13,"interventionNames":10},"Pregnant women with obesity\u002FGDM\u002FT2DM- Controls","Pregnant women with normal BMI\u002F no GDM orT2DM",{"label":15,"type":10,"description":16,"interventionNames":17},"Post-bariatric pregnant women","Pregnant women with previous bariatric surgery",[18],"Other: Observational",{"label":20,"type":10,"description":21,"interventionNames":10},"Pregnant no bariatric women- Controls","There will be two control groups of women with no previous bariatric surgery:\n\n1\\. Pregnant women with booking BMI similar to the booking BMI of the post-bariatric ones and 2. Pregnant women with booking BMI similar to the pre-surgery BMI of the post-bariatric ones.",[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Observational","This is an observational study",[15],[28],{"name":29,"affiliation":30,"role":31},"MAKRINA SAVVIDOU, MD","CHELSEA & WESTMINSTER HOSPITAL NHS FT","PRINCIPAL_INVESTIGATOR",[33,37],{"name":34,"role":35,"phone":10,"phoneExt":10,"email":36},"DAMON FOSTER","CONTACT","damon.foster2@nhs.net",{"name":38,"role":35,"phone":10,"phoneExt":10,"email":39},"DORIS DABY","doris.daby1@nhs.net",[41],{"facility":42,"status":43,"city":44,"state":10,"zip":10,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Chelsea & Westminster Hospital Nhs Ft","RECRUITING","London","United Kingdom","UK",{"type":48,"coordinates":49},"Point",[50,51],-0.12574,51.50853,{"lat":51,"lon":50},[54],{"name":29,"role":35,"phone":10,"phoneExt":10,"email":55},"m.savvidou@imperial.ac.uk",{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100497121","effect-of-obesity-diabetes-and-bariatric-surgery-on-pregnancy-outcomes-100497121",false,"NCT05753124","Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes","Investigation and Study of Pregnancy in Overweight or Diabetic Women and the Effect of Bariatric Surgery on Pregnancy Outcomes","Inclusion Criteria:\n\n* Pregnant women with normal size (BMI \\\u003C30)\n* Pregnant women with obesity (BMI ≥30)\n* Pregnant women with glucose disorders\n* Pregnant women with previous bariatric surgery\n\nExclusion Criteria:\n\n* Pregnant women less than 18 years of age\n* Pregnant women with twins\u002Ftriplets",true,"FEMALE","18 Years","50 Years",{"count":70,"type":71},700,"ESTIMATED","OBSERVATIONAL","The obesity epidemic is growing worldwide and in the UK this is perpetuated with a third of women classified as overweight\u002Fobese in 2020. Many of these woman are of childbearing age and go on to have high risk pregnancies which are often complicated by gestational or pre-existing (type 2 diabetes mellitus (GDM, T2DM). Bariatric surgery is the most successful treatment of sustainable weight loss and is associated with a reduction in rates of GDM, pre-eclampsia, delivery of large babies but increased risk of delivery of small babies and preterm delivery.\n\nThe aims of the study are to investigate the maternal and fetal\u002Fneonatal, biophysical and biochemical, intra-uterine environment and postnatal profile of pregnancies:\n\n1. affected by maternal obesity and\u002For GDM\u002FT2DM compared to pregnancies with normal maternal body mass index (BMI).\n2. with previous maternal bariatric surgery compared to pregnancies without previous bariatric surgery but matched for maternal pre-surgery and early pregnancy BMI.",[75,76,77,78,79],"Obesity","Pregnancy in Diabetic","Pregnancy Complications","Pregnancy Related","Bariatric Surgery Status Complicating Pregnancy",[81,82,83,84,85,86],"Pregnancy","Gastric sleeve","Gastric bypass","Bariatric surgery","Birth weight","Glucose intolerance","2023-03-01",{"date":89,"type":90},"2023-03-03","ACTUAL",{"date":92,"type":90},"2015-05",{"date":94,"type":71},"2027-10",{"name":5,"class":6},1]