[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612356":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":48,"responsibleParty":72,"collaborators":76,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":26,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":26,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":50,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Bangladesh Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental (PTX+ CoQ10)","EXPERIMENTAL","Participants receive pentoxifylline 400mg orally twice daily plus Coenzyme Q10 100mg twice daily orally",[13],"Combination Product: Pentoxifylline 400 MG Oral Tablet",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Comparator (Coenzyme Q10)","ACTIVE_COMPARATOR","Participants receive Coenzyme Q10 100mg twice daily orally",[19],"Dietary Supplement: Coenzyme Q 10",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Coenzyme Q 10","Participants will receive Coenzyme Q10 100 mg twice daily for 3 months",[15],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"COMBINATION_PRODUCT","Pentoxifylline 400 MG Oral Tablet","Participants will receive pentoxifylline 400mg twice daily plus coenzyme Q10 100mg twice daily for 3 months",[9],[33],"Coenzyme Q10",[35],{"name":36,"affiliation":5,"role":37},"Jesmine Banu, MS","PRINCIPAL_INVESTIGATOR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":26,"email":43},"Mst.Sumyara Khatun, MS","CONTACT","+8801746046581","sumirmc09@gmail.com",{"name":45,"role":41,"phone":46,"phoneExt":26,"email":47},"Kazi Jannatul Ferdouse, MBBS","+8801715595597","jannatulferdouse420@gmail.com",[49],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Dhaka","Shahbag","1000","Bangladesh","BD",{"type":57,"coordinates":58},"Point",[59,60],90.40744,23.7104,{"lat":60,"lon":59},[63,65,67,69],{"name":64,"role":41,"phone":42,"phoneExt":26,"email":43},"Mst Sumyara Khatun Medical officer, MS",{"name":66,"role":41,"phone":46,"phoneExt":26,"email":47},"Kazi Jannatul ferdouse",{"name":68,"role":37,"phone":26,"phoneExt":26,"email":26},"Kazi Jannatul Ferdouse",{"name":70,"role":71,"phone":26,"phoneExt":26,"email":26},"Jemine Banu, MS","SUB_INVESTIGATOR",{"type":73,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Mst.Sumyara Khatun","Medical officer",[77],{"name":5,"class":6},"100612356","effect-of-pentoxifylline--coq10-vs-coq10-alone-on-sperm-motility-in-subfertile-men-with-asthenozoospermia-100612356",false,"NCT07252518","Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia","Effect of Pentoxifylline Plus Coenzyme Q10 Combination Therapy Compared to Coenzyme Q10 Alone on Sperm Motility in Sub-fertile Male With Asthenozoospermia","Inclusion Criteria:\n\n* Sub fertile men with asthenozoospermia(Total motility20% to less than 42%) according to WHO semen analysis,2021.\n* Age 20-50 years.\n\nExclusion Criteria:\n\n* Severe oligoasthenoteratozoospermia\n* Any medical, endocrine and genetic disorders, history of chemotherapy or radiotherapy, genital infection, genital surgery.\n* Antioxidants supplmentation in the last 3 months\n* Drug, alcohol or substance abuse, psycho-sexual abnormalities.\n* Any known hypersensitivity to xanthine related product, recent cerebral or retinal haemorrhage Severe oligoasthenoteratozoospermia\n* Any medical, endocrine and genetic disorders, history of chemotherapy or radiotherapy, genital infection, genital surgery.\n* Antioxidants supplmentation in the last 3 months\n* Drug, alcohol or substance abuse, psycho-sexual abnormalities.\n* Any known hypersensitivity to xanthine related product, recent cerebral or retinal haemorrhage","MALE","20 Years","50 Years",{"count":89,"type":90},56,"ESTIMATED","INTERVENTIONAL",[93],"NA","The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10. The main questions it aims to answer are:\n\nDoes drug Pentoxifylline plus Coenzyme Q10 increase the motility of sperm in participants? What medical problems do participants have when taking drug Pentoxifylline plus Coenzyme Q10 ? Researchers will compare drug Pentoxifylline plus Coenzyme Q10 combination to Coenzyme Q10 alone to see if drug Pentoxifylline plus Coenzyme Q10 combination works better.\n\nParticipants will:\n\nExperimental Group:Pentoxifylline 400mg twice dailyand Coenzyme Q10 100mg twice daily for 3 months.\n\nComparator Group: Coenzyme Q10 100mg twice daily for 3 months Visit the clinic after three months of treatment for checkups and tests",[96],"Asthenozoospermia",[96,98,33],"Pentoxifylline","2025-11-24",{"date":101,"type":102},"2025-11-26","ACTUAL",{"date":104,"type":102},"2025-10-01",{"date":106,"type":90},"2027-03-01",{"name":74,"class":6},1]