[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575490":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":77,"collaborators":25,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":25,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":25,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":25,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TEAS group","EXPERIMENTAL","Transcutaneous electrical acupoint stimulation (TEAS) merges transcutaneous electrical nerve stimulation with acupoint therapy. It has its roots in acupuncture and shares similar effects, while being distinguished by its simplicity, safety, non-invasiveness, and reduced complications. TEAS functions by stimulating nerve fiber endings, which generates action potentials that are transmitted to the spinal cord and brain, subsequently triggering the release of related chemical mediators and producing corresponding physiological effects.\n\nIn this study, the traditional acupoints Taiyuan on the lung meridian and Hegu on the large intestine meridian were selected. The lung and large intestine meridians are interconnected, so the combined application of Taiyuan and Hegu acupoints with TEAS can produce a synergistic effect. This combination enhances the replenishment of lung qi, promotes the flow of meridians, regulates qi, and disseminates lung functions. It can stimulate effective",[13],"Other: Transcutaneous electrical acupoint stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","PLACEBO_COMPARATOR","conventional care plan",[19],"Other: Conventional care plan",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Transcutaneous electrical acupoint stimulation","In this study, the traditional acupoints Taiyuan (LU9) on the lung meridian and Hegu (LI4) on the large intestine meridian were selected. The lung and large intestine meridians are interconnected, so the combined application of Taiyuan and Hegu acupoints with TEAS can produce a synergistic effect. This combination enhances the replenishment of lung qi, promotes the flow of meridians, regulates qi, and disseminates lung functions. It can stimulate effective breathing in patients, thus positively influencing the improvement of their oxygen saturation levels.",[9],null,{"type":6,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"Conventional care plan",[15],[30],{"name":31,"affiliation":32,"role":33},"xiaoliang wang","The First Affiliated Hospital with Nanjing Medical University","STUDY_DIRECTOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"hua guan","CONTACT","+8618951670974","821278639@qq.com",[41,66],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Nanjing First Hospital","RECRUITING","Nanjing","Jiangsu","210006","China","CN",{"type":50,"coordinates":51},"Point",[52,53],118.77778,32.06167,{"lat":53,"lon":52},[56,60,63],{"name":57,"role":37,"phone":58,"phoneExt":25,"email":59},"zhang ying, Master degree","86+15380998716","1070434273@qq.com",{"name":61,"role":37,"phone":62,"phoneExt":25,"email":25},"wang xiao liang, Doctor","86+13776615743",{"name":64,"role":65,"phone":25,"phoneExt":25,"email":25},"wang xiao liang, Doctor degree","PRINCIPAL_INVESTIGATOR",{"facility":42,"status":67,"city":44,"state":45,"zip":68,"country":47,"countryCode":48,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"NOT_YET_RECRUITING","221006",{"type":50,"coordinates":70},[52,53],{"lat":53,"lon":52},[73],{"name":74,"role":37,"phone":75,"phoneExt":25,"email":76},"Xiaoliang Wang","+8613776615743","wxl145381@njmu.edu.cn",{"type":78,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100575490","effect-of-percutaneous-electrical-acupoint-stimulation-on-the-improvement-of-incidence-of-adverse-respiratory-events-100575490",false,"NCT06772961","Effect of Percutaneous Electrical Acupoint Stimulation on the Improvement of Incidence of Adverse Respiratory Events","Effect of Percutaneous Electrical Acupoint Stimulation on the Improvement of Incidence of Adverse Respiratory Events in the Emergence Period From General Anesthesia After Tracheal Extubation: A Single-center Randomized Controlled Study","Inclusion Criteria:\n\n* 1: Age \\>18 years old.\n\n  2: ASA I-III\n\n  3: Patients undergoing elective general anesthesia surgery who are extubated upon arrival to the PACU\n\nExclusion Criteria:\n\n* 1: Preoperative comorbidities include severe cardiovascular or respiratory diseases\n\n  2: Serious reflux aspiration during the perioperative period\n\n  3: Concurrent psychiatric disorders\n\n  4: Local skin infections or nerve damage at the upper limb Taiyuan and Hegu acupoints",true,"ALL","18 Years","100 Years",{"count":91,"type":92},236,"ESTIMATED","INTERVENTIONAL",[95],"NA","The goal of this study is to investigate the effect of combined acupoint electrical stimulation at Taiyuan (LU9) and Hegu (LI4) on improving the incidence of respiratory adverse events after extubation in patients during the recovery period from general anesthesia.\n\nThe main content of this study involves selecting patients who have undergone general anesthesia and are admitted to the Post Anesthesia Care Unit (PACU), with an expected 236 participants. The researchers will randomly assign participants to either the TEAS group or the control group using a random number table. In the TEAS group, electrodes will be applied to the upper limbs at the Taiyuan and Hegu acupoints, without intravenous infusion, and connected to a stimulation device. The stimulation will use a frequency of 2\u002F100 Hz with sparse-dense waves, and the intensity will be adjusted to the maximum current that the patient can tolerate, starting at the time of extubation and continuing for 30 minutes. The control group will receive routine care. Throughout the process, no invasive procedures will be performed.\n\nIn the PACU, the participants will:\n\nBe positioned in a 30° head-up tilt position, with continuous ECG monitoring. The SpO2 alarm on the monitor will be set to 95%.\n\nThe same anesthesiologist will perform extubation according to the extubation criteria.\n\nAfter extubation, participants will receive routine oxygen therapy via a nasal cannula at 3L\u002Fmin with a CO2 end-expiratory monitoring module attached to the other end of the cannula. Simultaneously, the TEAS group will undergo transcutaneous electrical stimulation for 30 minutes, or the control group will receive routine care.\n\nParticipants will be observed in the PACU for at least 30 minutes. If no adverse events occur and the Steward score is ≥4, the patient will be deemed ready for discharge and escorted back to the ward. If there is any significant change in the patient's condition, they will be transferred to the ICU .\n\nIf any respiratory-related adverse events occur, measures such as awakening the patient, supporting the jaw, increasing oxygen flow, or administering mask oxygen will be taken to ensure patient safety, and these events will be recorded in the \"PACU Postoperative General Anesthesia Patient Condition Observation and Nursing Record.\"",[98,99,100,101],"Extubation","Respiratory Depression","Acupuncture Points","Hypoxia","2025-02-06",{"date":104,"type":105},"2025-02-10","ACTUAL",{"date":107,"type":105},"2025-01-25",{"date":109,"type":92},"2025-12-25",{"name":5,"class":6},2]