[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638846":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":35,"centralContacts":43,"locations":50,"responsibleParty":68,"collaborators":30,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":30,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":30,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":98,"whyStopped":30,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Ondokuz Mayıs University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Stable angina and periodontitis group (SAP group)","EXPERIMENTAL","Individuals with angiographically confirmed stable angina and periodontitis who will receive non-surgical periodontal therapy, including scaling and root planing",[13],"Procedure: Non-surgical periodontal therapy (scaling and root planing)",{"label":15,"type":10,"description":16,"interventionNames":17},"Periodontitis group (P group)","Individuals with angiographically confirmed cardiovascular health and periodontitis who will receive non-surgical periodontal therapy, including scaling and root planing",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Control group (C group)","ACTIVE_COMPARATOR","Periodontally healthy individuals with angiographically confirmed absence of coronary artery disease who will receive routine professional dental cleaning and standardized oral hygiene instruction",[23],"Procedure: Non-surgical periodontal therapy (Professional dental cleaning)",[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Non-surgical periodontal therapy (scaling and root planing)","Non-surgical periodontal therapy will include full-mouth scaling and root planing performed using hand instruments and\u002For ultrasonic devices to remove supra- and subgingival plaque and calculus.",[15,9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Non-surgical periodontal therapy (Professional dental cleaning)","Supragingival calculus and plaque removal with standardized oral hygiene instruction.",[19],[36,40],{"name":37,"affiliation":38,"role":39},"Sena Altintas, DDS","Ondokuz Mayis University Department of Periodontology","PRINCIPAL_INVESTIGATOR",{"name":41,"affiliation":38,"role":42},"Feyza Otan Ozden, Prof.","STUDY_DIRECTOR",[44,48],{"name":37,"role":45,"phone":46,"phoneExt":30,"email":47},"CONTACT","+905540270097","senaltintas144@gmail.com",{"name":41,"role":45,"phone":30,"phoneExt":30,"email":49},"feyza_otan@yahoo.com",[51],{"facility":52,"status":30,"city":53,"state":54,"zip":55,"country":56,"countryCode":30,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Ondokuz Mayis University","Samsun","Atakum","55270","Turkey (Türkiye)",{"type":58,"coordinates":59},"Point",[60,61],36.3361,41.27976,{"lat":61,"lon":60},[64],{"name":65,"role":45,"phone":66,"phoneExt":30,"email":67},"Ondokuz Mayis University Faculty of Dentistry","+90362 312 19 19 \u002F 8121","disinfo@omu.edu.tr",{"type":39,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Sena Altintas","Research assistant","100638846","effect-of-periodontal-therapy-on-asprosin-in-stable-angina-100638846",false,"NCT07591844","Effect of Periodontal Therapy on Asprosin in Stable Angina","Effect of Non-Surgical Periodontal Therapy on Serum Asprosin in Patients With Stable Angina","Inclusion Criteria:\n\n* Willingness to participate in the study and provide written informed consent\n* Age 18 years or older\n* No periodontal treatment within the past 6 months\n* No use of local or systemic antibiotics within the past 3 months\n\nExclusion Criteria:\n\n* Unwillingness to participate in the study or to provide informed consent\n* Age under 18 years\n* Use of local or systemic antibiotics for the treatment of widespread infection within the past 3 months\n* Receipt of periodontal treatment within the past 6 months\n* Pregnancy or lactation (for female participants)\n* History of acute myocardial infarction within the past 6 months",true,"ALL","18 Years","65 Years",{"count":83,"type":84},60,"ESTIMATED","INTERVENTIONAL",[87],"NA","This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis. Asprosin is a novel metabolic biomarker reported to have potential protective roles in cardiovascular diseases and inflammatory processes. The study also investigates the relationship between periodontal parameters and serum asprosin levels before and after periodontal therapy.",[90,91],"Stable Angina Pectoris","Periodontitis",[93,94,95,96,97],"Non-surgical periodontal treatment","cardiovascular disease","stable angina","asprosin","periodontitis","NOT_YET_RECRUITING","2026-05-11",{"date":101,"type":102},"2026-05-18","ACTUAL",{"date":104,"type":84},"2026-05-20",{"date":106,"type":84},"2026-10-20",{"name":5,"class":6},1]