[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100471855":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":64,"collaborators":26,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":26,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":93,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual Reality Group","EXPERIMENTAL","Patients have baseline data collected two weeks pre-intervention by assessing patient symptomatology using the dizziness handicap inventory, activities specific balance confidence questionnaires and a simulator sickness questionnaire remotely. Next, an interview will be conducted to collect information including age, sex, ethnicity, physical activity level and VR experience. Lastly, VR headset will be mailed to patients home address. A date for VR device tutorial will be discussed during this interview. Next patients will undergo 4 or 8 weeks of vestibular rehabilitation if diagnosed with unilateral or bilateral vestibular hypofunction respectively. This involves weekly 40-45 minute in-person sessions with a physiotherapist and three 20 minute sessions a day of at-home independent exercises. In addition, they will undergo an at home VR vestibular rehabilitation protocol that involves playing a video game projected on an android or apple device in a VR headset for 20 minutes daily.",[13],"Behavioral: Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","ACTIVE_COMPARATOR","Patients have baseline data collected two weeks pre-intervention by assessing patient symptomatology using the dizziness handicap inventory, activities specific balance confidence questionnaires and a simulator sickness questionnaire remotely. Next, an interview will be conducted to collect information including age, sex, ethnicity, physical activity level and VR experience. Next patients will undergo 4 or 8 weeks of vestibular rehabilitation if diagnosed with unilateral or bilateral vestibular hypofunction respectively. This involves weekly 40-45 minute in-person sessions with a physiotherapist and three 20 minute sessions a day of at-home independent exercises. In addition, they will undergo an at-home regime that consists of auditory stimulation while wearing a VR headset for 20 minutes daily.",[19],"Behavioral: Standard Vestibular Rehabilitation with Adjunct Auditory Intervention",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation","The virtual reality intervention will involve standard vestibular rehabilitation as described above and adjunct at home virtual reality video game. This video game will be projected on an android or apple device accommodated into a VR headset for 20 minutes daily until the vestibular rehabilitation is complete. This video will be congruent to current vestibular rehabilitation program exercises. Point-of-view games compatible with both Android and iOS devices will be evaluated by professionals to determine the game that is most representative of current evidence based exercises.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard Vestibular Rehabilitation with Adjunct Auditory Intervention","The control intervention will involve standard vestibular rehabilitation as described above and adjunct audio intervention while wearing the VR headset for 20 minutes daily until the vestibular rehabilitation is complete.",[15],[32],{"name":33,"affiliation":34,"role":35},"Desmond A Nunez, MD, MBA","Division of Otolaryngology, Department of Surgery, The University of British Columbia","PRINCIPAL_INVESTIGATOR",[37,43],{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},"Austin Heffernan, BMSc","CONTACT","604-875-4111","61621","aheff12@student.ubc.ca",{"name":44,"role":39,"phone":40,"phoneExt":41,"email":45},"Lindsay E Booth, BSc","lbooth98@student.ubc.ca",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Vancouver","British Columbia","V6K2E8","Canada","CA",{"type":55,"coordinates":56},"Point",[57,58],-123.11934,49.24966,{"lat":58,"lon":57},[61],{"name":62,"role":39,"phone":63,"phoneExt":26,"email":42},"Austin Heffernan, MD","4165783035",{"type":35,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Desmond A Nunez","Head, Division of Otolaryngology - Head and Neck Surgery, The University of British Columbia; Staff Otolaryngologist, Vancouver Hospital & Health Sciences Centre","100471855","effect-of-peripheral-vestibular-disease-location-on-outcomes-following-home-based-virtual-reality-vestibular-therapy-100471855",false,"NCT05424302","Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy","Effect of Peripheral Vestibular Pathology Location on the Ability of Home-based Virtual Reality to Improve Symptoms of Peripheral Vestibular Disorders","VR-PVD-RCT","Inclusion Criteria:\n\n* Participants diagnosed with chronic (≥3 months) unilateral or bilateral peripheral vestibular disorders such as vestibular neuritis, labyrinthitis, Ramsay Hunt syndrome, ischemic lesion and trauma.\n* Diagnosis made using caloric testing (≥25% reduced vestibular response) and either ocular vestibular evoked myogenic potential (oVEMP) or cervical vestibular evoked myogenic potential (cVEMP) testing.\n* Participants prescribed vestibular rehabilitation\n* Participants ≥18 years of age\n* Access to an android or iOS smart phone\n\nExclusion Criteria:\n\n* Pregnant participants\n* Participant diagnosed with a central vestibular disorder",true,"ALL","18 Years",{"count":79,"type":80},50,"ESTIMATED","INTERVENTIONAL",[83],"NA","This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of adjunct take-home head-mounted display (HMD) virtual reality (VR) therapy in improving patient symptomatology. Fifty patients meeting inclusion criteria will be recruited from the principal investigator's neurotology clinic. Baseline symptomatology questionnaires will be completed, followed by random allocation to virtual reality and control groups. Vestibular rehabilitation and virtual reality protocols will be adhered to for 4 to 8 weeks, followed by symptomatology questionnaires. Data analysis will be conducted to answer the study's objectives.",[86,87,88,89,90,91,92],"Peripheral Vestibular Disorder","Benign Paroxysmal Positional Vertigo","Meniere Disease","Vestibular Neuritis","Vestibular Neuronitis","Labyrinthitis","Herpes Zoster Oticus",[94,95,96,97,98,89,90,91,92],"Virtual reality","Video games","Peripheral vestibular disorders","Benign paroxysmal positional vertigo","Meniere disease","2024-08-13",{"date":101,"type":102},"2024-08-15","ACTUAL",{"date":104,"type":102},"2024-06-01",{"date":106,"type":80},"2026-09",{"name":5,"class":6},1]