[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607870":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":26,"responsibleParty":45,"collaborators":19,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":19,"eligibilityCriteria":54,"healthyVolunteers":51,"sex":55,"minAge":56,"maxAge":19,"enrollmentInfo":57,"targetDuration":19,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":19,"overallStatus":29,"whyStopped":19,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hypo-\u002FHyperPP","EXPERIMENTAL","Strength exercise will be implemented for all participants included in this study. The first 12 weeks will be without intervention and after this period the intervention will begin. The participants are therefore all controls (no intervention) and experimental (intervention).",[13],"Other: Strength exercise",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Strength exercise","3 weekly supervised trainings with specific strengt exercises",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Annica B Enegaard","CONTACT","+4535456135","annica.buss.enegaard.01@regionh.dk",[27],{"facility":28,"status":29,"city":30,"state":19,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Rigshospitalet, Copenhagen Neuromuscular Center","RECRUITING","Copenhagen","2100","Denmark","DK",{"type":35,"coordinates":36},"Point",[37,38],12.56553,55.67594,{"lat":38,"lon":37},[41],{"name":42,"role":23,"phone":43,"phoneExt":19,"email":44},"John Vissing, Professor","+45 3545 6135","john.vissing@regionh.dk",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Annica Buss Enegaard","BSc","100607870","effect-of-physical-training-in-individuals-with-hypokalemic-and-hyperkalemic-periodic-paralysis-100607870",false,"NCT07194174","Effect of Physical Training in Individuals With Hypokalemic and Hyperkalemic Periodic Paralysis","Inclusion Criteria:\n\n* Patients with genetic verified HypoPP or HyperPP\n* Age minimum 18 years\n* Able to walk a minimum of 10 meters independently with or without assistive devices and be able to stand from a chair without using hands\n\nExclusion Criteria:\n\n* Other significant cause of muscle weakness\n* Heart or lung disease which, in the investigator's opinion, makes participation in the study training inadvisable\n\nExclusion from muscle biopsy\n\n* Anticoagulant treatment\n* Impaired blood clotting due to disease\n\nExclusion from MRI scanning due to:\n\n* Metal implants in the body that contraindicate MRI scanning or are positioned such that the scan quality is significantly affected\n* Claustrophobia\n* Pregnancy","ALL","18 Years",{"count":58,"type":59},36,"ESTIMATED","INTERVENTIONAL",[62],"NA","This study wishes to investigate the effects of strength exercise in patients with either HypoPP or HyperPP.\n\nThe investigators wishes to include participants already diagnosed with either HypoPP or HyperPP in af 24 week prospective study where the patients will be tested and asked to fill out questionnaires three times. These appointments will be schedueled at week 0, week 12 and week 24.\n\nIn the time period between week 12 and week 24, the patients will have a personalized strength exercise program, which they will have to follow these 3 months. The exercise will be supervised by one or more of the investigators.\n\nWe will also assess the muscle structure and function cross sectionally.",[65,66],"Hypokalemic Periodic Paralysis","Hyperkalemic Periodic Paralysis","2026-03-24",{"date":69,"type":70},"2026-03-30","ACTUAL",{"date":72,"type":70},"2025-10-02",{"date":74,"type":59},"2026-12-01",{"name":5,"class":6},1]