[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634866":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":7,"responsibleParty":18,"collaborators":7,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":26,"acronym":7,"eligibilityCriteria":27,"healthyVolunteers":24,"sex":28,"minAge":29,"maxAge":29,"enrollmentInfo":30,"targetDuration":33,"studyType":34,"phases":7,"briefSummary":35,"conditions":36,"keywords":38,"overallStatus":43,"whyStopped":7,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":7},{"fullName":5,"class":6},"Fayoum University","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"VExUS score","The Venous Excess Ultrasound Score (VExUS) was calculated for each patient based on the assessment of systemic venous congestion using the following parameters: Inferior vena cava (IVC) diameter and respiratory collapsibility, Hepatic vein Doppler waveform, Portal vein Doppler pulsatility and Intrarenal venous Doppler pattern.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Hager R. Elsofey, MBBCh","CONTACT","+201153153624","hra13@fayoum.edu.eg",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Hager Rabie Elsofey Mohammed","Assistant Lecturer of Critical Care Medicine","100634866","effect-of-positive-end-expiratory-pressure-titration-on-venous-excess-ultrasound-score-and-renal-outcomes-in-patients-with-acute-respiratory-distress-syndrome-100634866",false,"NCT07545252","Effect of Positive End-Expiratory Pressure Titration on Venous Excess Ultrasound Score and Renal Outcomes in Patients With Acute Respiratory Distress Syndrome","Inclusion Criteria:\n\n* Age ≥18 years.\n* Diagnosis of ARDS according to the Berlin criteria.\n* Invasive mechanical ventilation ≥24 hours.\n* Requirement of PEEP ≥5 cmH₂O.\n\nExclusion Criteria:\n\n* Known end-stage renal disease on chronic dialysis.\n* History of renal transplantation.\n* Pregnancy.\n* Known severe tricuspid regurgitation.\n* Chronic liver disease with portal hypertension.\n* Poor ultrasound window precluding adequate venous Doppler assessment.","ALL","18 Years",{"count":31,"type":32},40,"ESTIMATED","3 Days","OBSERVATIONAL","This study is a prospective observational cohort study conducted planned to include 40 patients with ARDS to assess the effect of different levels of PEEP titration on VExUS score and renal outcomes in patients with Acute Respiratory Distress Syndrome.",[37],"Acute Respiratory Distress Syndrome (ARDS)",[39,40,41,42],"ARDS","mechanically ventilatuon","PEEP Titration","VExUS","NOT_YET_RECRUITING","2026-04-16",{"date":46,"type":47},"2026-04-22","ACTUAL",{"date":49,"type":32},"2026-04-12",{"date":51,"type":32},"2026-10-12",{"name":5,"class":6}]