[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620470":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":42,"responsibleParty":57,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"A","EXPERIMENTAL","Patients undergo closed-circuit endotracheal suctioning without a recruitment maneuver.",[13],"Procedure: Closed-circuit endotracheal suctioning",{"label":15,"type":10,"description":16,"interventionNames":17},"B","Patients undergo closed-circuit endotracheal suctioning immediately followed by a recruitment maneuver.",[18],"Procedure: Suction + Recruitment maneuver",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Suction + Recruitment maneuver","After suctioning, a recruitment maneuver is applied consisting of an airway pressure of 30 cmH₂O maintained for 30 seconds, without changing the positive end-expiratory pressure.",[15],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Closed-circuit endotracheal suctioning","Standard closed-circuit endotracheal suctioning performed for less than 15 seconds without disconnecting the ventilator.",[9],[31],{"name":32,"affiliation":33,"role":34},"Cyril PERNOD, MD","Hôpital National d'Instruction des Armées (HNIA) Sainte-Anne, Toulon","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Asmaa JOBIC, Ph.D","CONTACT","04 83 77 20 61","+33","asmaa.jobic@ch-toulon.fr",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":25},"Hôpital National d'Instruction des Armées Sainte-Anne","RECRUITING","Toulon","VAR","83000","France","FR",{"type":52,"coordinates":53},"Point",[54,55],5.92836,43.12442,{"lat":55,"lon":54},{"type":58,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100620470","effect-of-post-suction-recruitment-on-lung-volume-in-mechanically-ventilated-icu-patients-100620470",false,"NCT07358039","Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients","Impact of a Recruitment Maneuver After Closed Endotracheal Suctioning on End-expiratory Lung Volume in Mechanically Ventilated ICU Patients Assessed by Electrical Impedance Tomography","RESPIRE","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Covered by national health insurance\n* Admitted to the intensive care unit\n* Intubated and mechanically ventilated\n* Neuromuscular blockade at inclusion\n* Written informed consent obtained from a legally authorized representative or next of kin\n\nExclusion Criteria:\n\n* Contraindication to electrical impedance tomography (e.g. pacemaker, implantable cardioverter-defibrillator, or implanted electrical stimulation device)\n* Contraindication to recruitment maneuvers (e.g. emphysema, undrained pneumothorax, hemodynamic instability)\n* Refractory intracranial hypertension\n* Acute respiratory distress syndrome requiring prone positioning\n* Pregnant or breastfeeding women\n* Patients deprived of liberty or under legal protection\n* Any condition judged by the investigator to interfere with study evaluation","ALL","18 Years",{"count":70,"type":71},32,"ESTIMATED","INTERVENTIONAL",[74],"NA","Patients who are intubated and mechanically ventilated in the intensive care unit (ICU) require repeated endotracheal suctioning to remove airway secretions. Although this procedure is necessary, it can cause a temporary collapse of lung units (alveolar derecruitment), leading to a decrease in lung volume and impaired oxygenation.\n\nA recruitment maneuver consists of briefly applying a higher airway pressure after suctioning in order to reopen collapsed lung areas and restore lung volume. However, the clinical benefit of performing a recruitment maneuver systematically after suctioning remains uncertain.\n\nThis study aims to evaluate whether performing a recruitment maneuver immediately after closed-circuit endotracheal suctioning improves lung volume compared with suctioning alone. Lung volume will be assessed using electrical impedance tomography (EIT), a non-invasive bedside imaging technique that allows real-time monitoring of lung aeration.\n\nIn a randomized crossover design, each patient will undergo two suctioning procedures: one followed by a recruitment maneuver and one without, in a random order. The main outcome will be the change in end-expiratory lung volume 15 minutes after suctioning. The results may help optimize ventilatory care in mechanically ventilated ICU patients.",[77],"Mechanical Ventilation",[79,80,81,82,83,84],"Endotracheal suction","Alveolar recruitment","Electrical impedance tomography","End-expiratory lung volume","Intensive care","Mechanical ventilation","2026-06-15",{"date":87,"type":88},"2026-06-16","ACTUAL",{"date":90,"type":88},"2026-04-02",{"date":92,"type":71},"2027-04",{"name":5,"class":6},1]